{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T18:38:45Z","timestamp":1791571125366,"version":"4.3.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T00:00:00Z","timestamp":1530748800000},"content-version":"vor","delay-in-days":95,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultrasound Int Open"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p> The purpose of the study is to clarify the prevalence of calcifications within thyroid tumors on ultrasonography as well as the relationship between the calcification and histopathological types.<\/jats:p><jats:p>\nCalcifications were classified into 6 (or 8) types according to their shape, size, and region. The prevalence of calcifications and types were investigated in new outpatients and patients who underwent thyroid surgery.<\/jats:p><jats:p>Among 2,902 nodules in 2,678 new outpatients, 747 nodules (26%) had calcifications. The types showed a wide distribution. Among 941 patients with papillary carcinoma (PC), 725 patients (77%) had calcifications, and the types showed a wide distribution. 18 patients with the diffuse sclerosing variant of PC only showed punctate microcalcifications in the parenchyma (100%), 32 patients with the cyst-forming type of PC mostly fragmentary and massive types (100%), and 161 metastatic lymph nodes from PC mostly punctate microcalcifications and fragmentary types (48%). Among 337 patients with follicular carcinoma, 79 patients (23%) had calcifications, and the types were mostly fragmentary, massive, and egg-shell types. Among 41 patients with undifferentiated carcinoma, 33 patients (80%) presented with calcifications, which were mostly the massive and egg-shell types. Among 137 patients with medullary carcinoma, 99 patients (72%) had calcification, and the types showed a wide distribution. None of 173 patients with primary thyroid lymphoma had calcifications (0%).<\/jats:p><jats:p>Calcifications on ultrasonography can be one of the characteristic findings and a full understanding of the prevalence of calcifications and types will markedly contribute to the ultrasonic diagnosis of thyroid tumors.<\/jats:p>","DOI":"10.1055\/a-0591-6070","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T22:40:17Z","timestamp":1530830417000},"page":"E45-E51","source":"Crossref","is-referenced-by-count":26,"title":["Calcifications in Thyroid Tumors on Ultrasonography: Calcification Types and Relationship with Histopathological Type"],"prefix":"10.1055","volume":"04","author":[{"given":"Kaoru","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Hospital, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuyoshi","family":"Hirokawa","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Kuma Hospital, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonori","family":"Yabuta","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroo","family":"Masuoka","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Higashiyama","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Kihara","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Miya","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kuma Byoin, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,7,5]]},"container-title":["Ultrasound International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0591-6070.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T20:45:42Z","timestamp":1557175542000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0591-6070"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2018,7,5]]},"published-print":{"date-parts":[[2018,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0591-6070","relation":{},"ISSN":["2509-596X","2199-7152"],"issn-type":[{"value":"2509-596X","type":"print"},{"value":"2199-7152","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4]]}}}