{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T03:19:50Z","timestamp":1785467990033,"version":"3.56.0"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"07","license":[{"start":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T00:00:00Z","timestamp":1530662400000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background and study aims\u2002Endoscopic negative pressure therapy (ENPT) has been developed to treat gastrointestinal leakages. Up to now, ENPT has usually been performed with open-pore polyurethane foam drains (OPD). A big disadvantage of the OPDs is their large diameter. We have developed a new, small-bore open-pore film drainage (OFD). Herein we report our first experience in a case series of 16 patients.<\/jats:p>\n                  <jats:p>Patients and methods\u2002OFD is constructed with a drainage tube and a very thin double-layered open-pore drainage film (Suprasorb CNP, Drainage Film, Lohmann &amp; Rauscher International, Germany). The distal end of the tube is wrapped with only one layer of film. OFD is placed into the gastrointestinal leakage site with common endoscopic techniques. The tube is connected to an electronic vacuum device and continuous negative pressure of \u2013125\u200ammHg applied.<\/jats:p>\n                  <jats:p>Results\u2002From 2013 to 2016, 16 patients were treated with the new OFD device. In 10 patients, transmural intestinal defects (4 esophageal, 4 rectum\/colon, 1 duodenal, 1 pancreatic cyst) were closed with ENPT in median time of 12 days (range 3\u200a\u2013\u200a34 days). Five of the 10 patients were treated solely with OFD devices. In five patients ENPT started with ODP and changed to OFD when the cavity was shrunken to a channel with a small opening. In four patients postoperative gastric reflux was eliminated for 5 to 16 days.<\/jats:p>\n                  <jats:p>Conclusions\u2002Small-bore OFD opens up promising new treatment options within ENPT. OFD can be used in endoscopic closure management of intestinal leakages in the upper and lower gastrointestinal tract. Gastric reflux can be eliminated in an active manner. OFD can be inserted nasally. OFD may be an adequate substitute for OPD, especially when placement of the larger OPD is difficult.<\/jats:p>\n                  <jats:p>Meeting presentations: The authors\u02bc experience was first reported in an oral presentation at the 46th Kongress der Deutschen Gesellschaft f\u00fcr Endoskopie und Bildgebende Verfahren in Mannheim (DGE-BV), 17.\u200a\u2013\u200a19.03.2016.<\/jats:p>","DOI":"10.1055\/a-0599-5886","type":"journal-article","created":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T18:52:17Z","timestamp":1530730337000},"page":"E865-E871","source":"Crossref","is-referenced-by-count":71,"title":["Open-pore film drainage (OFD): A new multipurpose tool for endoscopic negative pressure therapy (ENPT)"],"prefix":"10.1055","volume":"06","author":[{"given":"Gunnar","family":"Loske","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schorsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Rucktaeschel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Schulze","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhard","family":"Riefel","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"van Ackeren","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Theodor","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department for General, Abdominal, Thoracic and Vascular Surgery, Katholisches Marienkrankenhaus Hamburg gGmbH, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,7,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1007\/s00464-007-9706-x","article-title":"Endoscopic vacuum-assisted closure of Anastomotic leakage following anterior resection of the rectum: a new method","volume":"22","author":"R Weidenhagen","year":"2008","journal-title":"Surg Endosc"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1007\/s00464-010-0998-x","article-title":"\u00a7#\/ITL#\u00a7 Endoscopic vacuum sponge therapy for esophageal defects","volume":"24","author":"G Loske","year":"2010","journal-title":"Surg Endosc"},{"key":"ref3","first-page":"7767","article-title":"Novel treatment options for perforations of the upper gastrointestinal tract: Endoscopic vacuum therapy and over-the-scope clips","volume":"20","author":"R Mennigen","year":"2014","journal-title":"Gastroenterol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1055\/s-0030-1256345","article-title":"Intraluminal and intracavitary vacuum therapy for esophageal leakage: a new endoscopic minimally invasive approach","volume":"43","author":"G Loske","year":"2011","journal-title":"Endoscopy"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"E148","DOI":"10.1055\/s-0042-106576","article-title":"Transgastric endoscopic vacuum therapy with a new open-pore film drainage device in a case of infective pancreatic necrosis","volume":"48","author":"G Loske","year":"2016","journal-title":"Endoscopy"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"E577","DOI":"10.1055\/s-0034-1393388","article-title":"Successful endoscopic vacuum therapy with new open-pore film drainage in a case of iatrogenic duodenal perforation during ERCP","volume":"47","author":"G Loske","year":"2015","journal-title":"Endoscopy"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"E410","DOI":"10.1055\/s-0034-1392597","article-title":"Endoscopic vacuum therapy in Boerhaave's syndrome with open-pore polyurethane foam and a new open-pore film drainage","volume":"47","author":"G Loske","year":"2015","journal-title":"Endoscopy"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s00104-016-0318-7","article-title":"First report of urinary endoscopic vacuum therapy: For large bladder defect after abdomino-perineal excision of the rectum. 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