{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T13:50:46Z","timestamp":1675345846209},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nIntroduction\/Background Atherosclerosis is an inflammatory disorder in which several converging immune responses modulate and induce lipid accumulation in macrophages. Activated leukocyte cell adhesion molecule (ALCAM) has been described as a structural homologue of HDL-receptor and functions as a pattern recognition receptor (PRR), while its soluble form sALCAM is involved in ALCAM-dependent and -independent immune mechanisms. The aim of this study was to investigate the effect of aggressive removal of low density lipoprotein-cholesterol (LDL-C) and lipoprotein(a) (Lp [a]) by lipoprotein-apheresis (LA) on sALCAM and blood viscosity as well as to evaluate its association with lipoproteins and serum markers of inflammation.<\/jats:p>","DOI":"10.1055\/a-0630-0232","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T23:33:07Z","timestamp":1528759987000},"page":"276-280","source":"Crossref","is-referenced-by-count":4,"title":["Pleiotropic Effect of Lipoprotein-Apheresis on the Soluble Form of Activated Leukocyte Cell Adhesion Molecule (sALCAM) in Familial Hypercholesterolaemia"],"prefix":"10.1055","volume":"127","author":[{"given":"R\u00fcdiger","family":"von Bauer","sequence":"additional","affiliation":[{"name":"SRH Kliniken GmbH, Karlsbad, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Oikonomou","sequence":"additional","affiliation":[{"name":"Internal Medicine 1 and Clinical Chemistry, University Hospital Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Sulaj","sequence":"additional","affiliation":[{"name":"Internal Medicine I, Universitatsklinikum Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Kopf","sequence":"additional","affiliation":[{"name":"Department of Medicine 1, University of Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Fleming","sequence":"additional","affiliation":[{"name":"University of Heidelberg, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gottfried","family":"Rudofsky","sequence":"additional","affiliation":[{"name":"Kantonsspital Olten, Olten, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Nawroth","sequence":"additional","affiliation":[{"name":"Internal Medicine 1 and Clinical Chemistry, Universit\u00e4tsKlinikum Heidelberg, Heidelberg, Baden-W\u00fcrttemberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,6,11]]},"container-title":["Experimental and Clinical Endocrinology &amp; Diabetes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0630-0232.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T22:52:32Z","timestamp":1557183152000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0630-0232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,11]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2019,5,6]]},"published-print":{"date-parts":[[2019,5]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0630-0232","relation":{},"ISSN":["0947-7349","1439-3646"],"issn-type":[{"value":"0947-7349","type":"print"},{"value":"1439-3646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,11]]}}}