{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:17:07Z","timestamp":1792149427714,"version":"4.4.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to measure the impact, at 24\u2009h post-exercise, of a single exercise bout on plasma inflammatory markers such as calprotectin, IL-6, sIL-6\u2009R, sgp130 and the hypothalamic-pituitary-adrenal (HPA) axis in children with juvenile idiopathic arthritis (JIA).<\/jats:p><jats:p>Twelve children with JIA attended the laboratory on three consecutive days (control day, exercise day and 24\u2009h post-exercise), including a 20-min exercise bout on a cycle-ergometer at 70% of max. HR at 8:30 a.m. on day 2. Plasma concentrations of calprotectin, IL-6, sIL-6\u2009R, sgp130, cortisol, ACTH and DHEA were measured on venous blood samples taken every day.at rest and at 8:30, 8:50, 9:30, 10:30 a.m. and 12:00, 3:00, 5:30\u2009p.m.<\/jats:p><jats:p>A single exercise bout increased plasma calprotectin 1.7-fold (p&lt;0.001) but did not increase IL-6 and soluble IL-6 receptors in short-term post-exercise recovery. However, at 24\u2009h post-exercise, calprotectin, IL-6 and its receptors had decreased compared to control-day levels. There was a transient 2-fold increase in post-exercise self-evaluated pain (p=0.03) that disappeared in the evening without repercussions the following day.<\/jats:p><jats:p>Physical activity in children with JIA results in a slight transient systemic inflammation but seems to be followed by counter-regulation at 24\u2009h post-exercise with a decrease in proinflammatory markers.<\/jats:p>","DOI":"10.1055\/a-0640-9063","type":"journal-article","created":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T22:35:26Z","timestamp":1534545326000},"page":"867-874","source":"Crossref","is-referenced-by-count":9,"title":["Inflammatory Response 24\u2009h Post-Exercise in Youth with Juvenile Idiopathic Arthritis"],"prefix":"10.1055","volume":"39","author":[{"given":"Emmanuelle","family":"Rochette","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Clermont-Ferrand, Pediatrie, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Merlin","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Clermont-Ferrand, Pediatrie, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Hourd\u00e9","sequence":"additional","affiliation":[{"name":"Biology of Motricity Laboratory, Universite Savoie Mont-Blanc, Chambery, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Evrard","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Clermont-Ferrand, Laboratoire d'immunologie, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Peraira","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Clermont-Ferrand, DRCI, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Echaubard","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Clermont-Ferrand, Pediatrie, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Duch\u00e9","sequence":"additional","affiliation":[{"name":"Universite Clermont Auvergne, AME2P, Clermont-Ferrand, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,8,17]]},"container-title":["International Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0640-9063.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T22:42:02Z","timestamp":1537915322000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0640-9063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,17]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,9,25]]},"published-print":{"date-parts":[[2018,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0640-9063","relation":{},"ISSN":["0172-4622","1439-3964"],"issn-type":[{"value":"0172-4622","type":"print"},{"value":"1439-3964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,17]]}}}