{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T16:44:13Z","timestamp":1786466653844,"version":"build-2736575974"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Endocrinol Diabetes"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nBackground We aimed to determine whether there is an increase in aortic intima-media thickness values measured from the abdominal aorta in addition to the traditional carotid intima-media thickness in patients with primary hyperparathyroidism and to determine the parameters closely related to aortic intima-media thickness.<\/jats:p><jats:p>\nMethods This perspective study included 65 primary hyperparathyroidism patients and 30 healthy-controls. Routine laboratory tests for the diagnosis of hyperparathyroidism and vascular ultrasound examinations were performed. Common carotid, internal carotid, and abdominal aortic intima media thickness were measured. The participants of the study was divided into 3 groups as the control (Group\u2013I), the medical treatment (Group\u2013II) due to primary hyperparathyroidism, and the planned surgery (group\u2013III).<\/jats:p><jats:p>\nResults Aortic intima-media thickness, serum urea, creatinine, glucose, uric acid, hs-CRP, parathyroid hormone, calcium and urine calcium levels increased significantly from Group\u2013I to Group\u2013III and T\u2013scores and serum phosphorus in levels decreased significantly. Carotid intima-media thicknesses were not significantly different between the groups. Serum and urinary calcium levels were independently associated with aortic intima-media thickness. Aortic intima-media thickness, serum phosphorus, parathyroid hormone, T-scores, serum and urinary calcium levels are independent indicators for Group\u2013III. When the cut-off value of aortic intima-media thickness was taken as 1.5\u2009mm, 80.6% sensitivity and 89.1% specificity were determined for patients who would go to surgery.<\/jats:p><jats:p>\nConclusion Serum and urine calcium levels were independently associated with aortic intima-media thickness. Aortic intima-media thickness is more useful than carotid intima-media thickness in showing vascular organ involvement in patients with primary hyperparathyroidism.<\/jats:p>","DOI":"10.1055\/a-0664-7820","type":"journal-article","created":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T22:38:26Z","timestamp":1534286306000},"page":"387-395","source":"Crossref","is-referenced-by-count":11,"title":["The Abdominal Aortic Intima-Media Thickness Increases in Patients with Primary Hyperparathyroidism"],"prefix":"10.1055","volume":"127","author":[{"given":"Hilmi Erdem","family":"Sumbul","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Health Sciences - Adana Health Practice and Research Center, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Selcan","family":"Koc","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Health Sciences - Adana Health Practice and Research Center, Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,8,14]]},"container-title":["Experimental and Clinical Endocrinology &amp; Diabetes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0664-7820.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T23:00:57Z","timestamp":1559948457000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0664-7820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,14]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,6,7]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0664-7820","relation":{},"ISSN":["0947-7349","1439-3646"],"issn-type":[{"value":"0947-7349","type":"print"},{"value":"1439-3646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,14]]}}}