{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T04:22:09Z","timestamp":1769919729926,"version":"3.49.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An\u00e4sthesiol Intensivmed Notfallmed Schmerzther"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die anhaltende unkontrollierte Blutung ist eine der f\u00fchrenden Todesursachen bei polytraumatisierten Patienten 1,\u200a2,\u200a3,\u200a4,\u200a5. Hypoperfusion durch gro\u00dfe Blutverluste f\u00fchrt zu Gewebesch\u00e4den, generalisierter Immunantwort sowie Aktivierung des Gerinnungssystems und damit zu einer traumaassoziierten Koagulopathie (TAK) 4,\u200a5. Durch eine ad\u00e4quate, fr\u00fchzeitige Behandlung der TAK k\u00f6nnen Morbidit\u00e4t und Mortalit\u00e4t signifikant reduziert werden.<\/jats:p>","DOI":"10.1055\/a-0736-7559","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T22:31:12Z","timestamp":1560897072000},"page":"413-423","source":"Crossref","is-referenced-by-count":2,"title":["Traumaassoziierte Koagulopathie: Pathophysiologie und Therapie"],"prefix":"10.1055","volume":"54","author":[{"given":"Christine","family":"Schl\u00f6mmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Meier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,6,18]]},"container-title":["AINS - An\u00e4sthesiologie \u00b7 Intensivmedizin \u00b7 Notfallmedizin \u00b7 Schmerztherapie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0736-7559.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T22:31:20Z","timestamp":1560897080000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0736-7559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,6,18]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0736-7559","relation":{},"ISSN":["0939-2661","1439-1074"],"issn-type":[{"value":"0939-2661","type":"print"},{"value":"1439-1074","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}