{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T22:26:32Z","timestamp":1749853592863},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Die bisher ver\u00f6ffentlichte Studienlage zur Assoziation von Kolondivertikeln und kolorektalen Polypen einschlie\u00dflich des kolorektalen Karzinoms (KRK) ist kontr\u00e4r. Ziel der Studie war es, die Assoziation f\u00fcr s\u00e4mtliche relevanten histologischen Polypensubtypen, d.\u200ah. hyperplastische Polypen (HP), sessil und traditionell serratierte Adenome (SSA und TSA), klinisch relevante serratierte Polypen (krSP), tubul\u00e4re Adenome und fortgeschrittene Adenome in einer ausschlie\u00dflichen Vorsorgekoloskopie-Kohorte zu untersuchen.<\/jats:p><jats:p>\n          Material und Methoden\u2002Wir f\u00fchrten eine retrospektive Analyse von Personen \u2265\u200a50 Jahre und einem durchschnittlichen Risiko f\u00fcr ein KRK, die eine Vorsorgekoloskopie zwischen dem 01.01.2012 und dem 14.12.2016 in einer Universit\u00e4tsklinik und 6 gastroenterologischen Schwerpunktpraxen erhalten haben, durch. Ausschlusskriterien waren Erkrankungen mit einem erh\u00f6hten KRK-Risiko (z.\u200aB. chronisch-entz\u00fcndliche Darmerkrankungen, KRK in der Vorgeschichte, heredit\u00e4re Karzinomsyndrome), eine vorherige Koloskopie und eine unvollst\u00e4ndige Untersuchung.<\/jats:p><jats:p>\n          Ergebnisse\u20024196 Koloskopien wurden eingeschlossen (mittleres Alter 63,4 Jahre, Standardabweichung \u00b1\u200a7,6 Jahre, 48,6\u200a%). Bei Vorliegen von Divertikeln zeigten sich nach Adjustierung f\u00fcr Alter und Geschlecht erh\u00f6hte Odds-Ratios (OR) f\u00fcr den Nachweis von HP im gesamten (OR 1,340, 95\u200a%-Konfidenzintervall 1,133\u200a\u2013\u200a1,584, p\u200a=\u200a0,001) und im distalen Kolon (OR 1,459, 95\u200a%-KI 1,208\u200a\u2013\u200a1,763, p\u200a&lt;\u200a0,001) sowie von tubul\u00e4ren Adenomen im distalen Kolon (OR 1,355, 95\u200a%-KI 1,144\u200a\u2013\u200a1,604, p\u200a&lt;\u200a0,001). Die mittlere Polypenanzahl pro Untersuchung mit dem Nachweis von mindestens einem Polypensubtypen unterschied sich nicht zwischen beiden Gruppen.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Die Untersucher sollten beim Vorliegen einer Divertikulose wachsam f\u00fcr den Nachweis von vor allem distal gelegenen Adenomen sein.<\/jats:p>","DOI":"10.1055\/a-0755-2448","type":"journal-article","created":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T10:16:56Z","timestamp":1544523416000},"page":"1475-1480","source":"Crossref","is-referenced-by-count":3,"title":["Hyperplastic polyps and nonadvanced adenomas, but not advanced polypoid lesions, are detected more frequently in the presence of colonic diverticula during screening colonoscopies"],"prefix":"10.1055","volume":"56","author":[{"given":"Christoph","family":"Schramm","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"K\u00fctting","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja","family":"Lang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Kasper","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Hun","family":"Chon","sequence":"additional","affiliation":[{"name":"General, Visceral and Cancer Surgery, University Hospital Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Michael","family":"Steffen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University Hospital Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,12,10]]},"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0755-2448.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T10:17:06Z","timestamp":1544523426000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0755-2448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2018,12,10]]},"published-print":{"date-parts":[[2018,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0755-2448","relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]}}}