{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:25:24Z","timestamp":1790162724738,"version":"4.1.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The relevance of gastrointestinal manifestations of cystic fibrosis (CF) is increasing due to an improved life expectancy. We report on 2 adult patients with prior lung transplantation who presented with a severe inflammatory disorder of the ileocecal region. One patient underwent ileocecal resection; the second patient died after emergency surgery for intestinal perforation. Both cases did not show typical signs of CF-related distal intestinal obstruction syndrome or extensive fibrosing colonopathy. However, the clinical and histopathological findings revealed CF-induced inflammatory alterations of the\u00a0intestinal mucosa. Thus, these cases illustrate a further CF-related bowel disorder, which can be especially relevant in long-term CF survivors.<\/jats:p>","DOI":"10.1055\/a-0829-7050","type":"journal-article","created":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T23:36:00Z","timestamp":1552433760000},"page":"312-316","source":"Crossref","is-referenced-by-count":3,"title":["Severe ileocecal inflammatory syndrome in adult patients with cystic fibrosis"],"prefix":"10.1055","volume":"57","author":[{"given":"Robert","family":"Henker","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Gastroenterology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annett","family":"Oltmanns","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Pulmonology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Wald","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Pulmonology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tuennemann","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Gastroenterology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Opitz","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Institute of Pathology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albrecht","family":"Hoffmeister","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Gastroenterology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Wirtz","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Pulmonology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"M\u00f6ssner","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Gastroenterology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Jansen-Winkeln","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Department of Visceral, Transplant, Thoracic and Vascular Surgery, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Karlas","sequence":"additional","affiliation":[{"name":"University Hospital Leipzig, Division of Gastroenterology, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,3,12]]},"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0829-7050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T23:36:15Z","timestamp":1552433775000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0829-7050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2019,3,12]]},"published-print":{"date-parts":[[2019,3]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0829-7050","relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]}}}