{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:47:19Z","timestamp":1759942039999},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fortschr Neurol Psychiatr"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Seit 2004 liegen Publikationen zum Einsatz von Levetiracetam beim Status epilepticus vor. In der vorliegenden Arbeit werden basierend auf einer PubMed-Literatur-Recherche vom 06.07.2018 die nach dem 12.12.2011 erschienenen Arbeiten zusammenfassend dargestellt und in der Diskussion mit den \u00e4lteren Arbeiten verglichen. Es wurden 28 Behandlungsepisoden in Berichten \u00fcber 1-2 F\u00e4lle und 412 Behandlungsepisoden in Fallserien und prospektiven Studien beschrieben. Dabei lie\u00df sich aus den Fallserien und Studien ein hochwahrscheinlicher Mittelwert der Erfolgsrate f\u00fcr die Status-Durchbrechung von 55,0\u200a%-59,4\u200a% ableiten. Auf-grund des zu vermutenden verz\u00f6gerten Wirkungseitritts des Levetiracetams ist sein Einsatz beim Status generalisierter tonisch-klonischer Anf\u00e4lle dennoch zu hinterfragen. Als Loading-Dosis erscheinen 30\u200amg\u200a\/\u200akg KG angemessen<\/jats:p>","DOI":"10.1055\/a-0832-8652","type":"journal-article","created":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T23:14:35Z","timestamp":1562022875000},"page":"357-363","source":"Crossref","is-referenced-by-count":1,"title":["Levetiracetam in der Behandlung des Status epilepticus \u2013 ein update"],"prefix":"10.1055","volume":"87","author":[{"given":"Johannes","family":"R\u00f6sche","sequence":"additional","affiliation":[{"name":"Klinikum Kassel GmbH, Klinik f\u00fcr Neurologie; Universit\u00e4t Rostock, Klinik und Poliklinik f\u00fcr Neurologie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Dudek","sequence":"additional","affiliation":[{"name":"Klinikum Kassel GmbH, Klinik f\u00fcr Neurologie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Teleki","sequence":"additional","affiliation":[{"name":"Klinikum Kassel GmbH, Klinik f\u00fcr Neurologie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Godau","sequence":"additional","affiliation":[{"name":"Klinikum Kassel GmbH, Klinik f\u00fcr Neurologie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"B\u00f6sel","sequence":"additional","affiliation":[{"name":"Klinikum Kassel GmbH, Klinik f\u00fcr Neurologie"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,7,1]]},"container-title":["Fortschritte der Neurologie \u00b7 Psychiatrie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0832-8652.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T23:14:41Z","timestamp":1562022881000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0832-8652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,6,24]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0832-8652","relation":{},"ISSN":["0720-4299","1439-3522"],"issn-type":[{"value":"0720-4299","type":"print"},{"value":"1439-3522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}