{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T16:01:16Z","timestamp":1762444876641},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"Abstract<\/jats:title>\n Background and aims\u2002This study examined differences in personality, psychological distress, and stress coping in inflammatory bowel disease (IBD) depending on type of disease and disease activity. We compared patients suffering from Crohn\u2019s disease (CD) and ulcerative colitis (UC) with controls. While the literature is replete with distinctive features of the pathogenesis of IBD, the specific differences in psychological impairments are not well studied.<\/jats:p>\n Methods\u2002In this German national multicenter study, participants were recruited from 32 centers. Two hundred ninety-seven questionnaires were included, delivering vast information on disease status and psychological well-being based on validated instruments with a total of 285 variables.<\/jats:p>\n Results\u2002CD patients were more affected by psychological impairments than patients suffering from UC or controls. Importantly, patients with active CD scored higher in neuroticism (p\u200a<\u200a0.01), psychological distress (p\u200a<\u200a0.001) and maladaptive stress coping (escape, p\u200a=\u200a0.03; rumination, p\u200a<\u200a0.03), but less need for social support (p\u200a=\u200a0.001) than controls. In\u00a0contrast, patients suffering from active UC showed psychological distress (p\u200a<\u200a0.04) and maladaptive coping (avoidance, p\u200a<\u200a0.03; escape, p\u200a=\u200a0.01). Patients in remission seemed to be less affected. In particular, patients with UC in remission were not inflicted by psychological impairments. The group of CD patients in remission however, showed insecurity (p\u200a<\u200a0.01) and paranoid ideation (p\u200a=\u200a0.04).<\/jats:p>\n Conclusions\u2002We identified specific aspects of psychological impairment in IBD depending on disease and disease activity. Our results underscore the need for psychological support and treatment particularly in active CD.<\/jats:p>","DOI":"10.1055\/a-0838-6371","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T22:50:20Z","timestamp":1554850220000},"page":"473-483","source":"Crossref","is-referenced-by-count":13,"title":["Perceived distress, personality characteristics, coping strategies and psychosocial impairments in a national German multicenter cohort of patients with Crohn\u2019s disease and ulcerative colitis"],"prefix":"10.1055","volume":"57","author":[{"given":"Vanessa","family":"Petruo","sequence":"additional","affiliation":[{"name":"Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekaterina","family":"Krauss","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Justus-Liebig University Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anika","family":"Kleist","sequence":"additional","affiliation":[{"name":"Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Hardt","sequence":"additional","affiliation":[{"name":"Berlin Institute of Health (BIH), Clinical Research Unit (CRU) \u2013 Biostatistics, Berlin, Germany"},{"name":"Institute of Biometry and Clinical Epidemiology (iBikE), Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin AND Berlin Institute of Health (BIH), Berlin, Germany"},{"name":"Institute for Social Medicine and Epidemiology, University of L\u00fcbeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karsten","family":"Hake","sequence":"additional","affiliation":[{"name":"University of Rostock, Clinic for Psychosomatics and Psychotherapic Medicine, Rostock, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Peirano","sequence":"additional","affiliation":[{"name":"Psychotherapy practice with focus on IBD, Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Krause","sequence":"additional","affiliation":[{"name":"Gastroenterological practice, Kassel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Ehehalt","sequence":"additional","affiliation":[{"name":"Gastroenterological practice, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"von Arnauld de la Perri\u00e9re","sequence":"additional","affiliation":[{"name":"Gastroenterological practice, L\u00fcneburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"B\u00fcning","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University Hospital of Schleswig-Holstein, Campus L\u00fcbeck, L\u00fcbeck, Germany and Gastroenterological Practice, L\u00fcbeck, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Treml","sequence":"additional","affiliation":[{"name":"Specialized Medical Center, Hagen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Krauss","sequence":"additional","affiliation":[{"name":"Center of Visceral Medicine, Gastroenterology, Endoscopy and Surgery, Justus-Liebig University Giessen, Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinz","family":"Albrecht","sequence":"additional","affiliation":[{"name":"Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela","family":"Felten","sequence":"additional","affiliation":[{"name":"Gastroenterological Practice, Herne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uta","family":"Hermannspahn","sequence":"additional","affiliation":[{"name":"Municipal Clinic of Landau i.d. Pfalz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Burkhardt","sequence":"additional","affiliation":[{"name":"Gastroenterological Practice, Plauen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Eisold","sequence":"additional","affiliation":[{"name":"Gastroenterological Practice, Moessingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nils","family":"Teich","sequence":"additional","affiliation":[{"name":"Gastroenterological Practice, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Britta","family":"Siegmund","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin, Medical Clinic I, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Maaser","sequence":"additional","affiliation":[{"name":"Outpatient\u2019s Department of Gastroenterology, University Teaching Hospital L\u00fcneburg, L\u00fcneburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Bokemeyer","sequence":"additional","affiliation":[{"name":"Gastroenterological practice, Minden"},{"name":"University Hospital of Schleswig-Holstein, Campus Kiel, Medical Clinic I, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Baumgart","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology. Charit\u00e9 Medical School, Humboldt-University, Berlin, Germany"},{"name":"Division of Gastroenterology, University of Alberta, Edmonton, AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Neurath","sequence":"additional","affiliation":[{"name":"Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Mudter","sequence":"additional","affiliation":[{"name":"Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany"},{"name":"Department of Gastroenterology and Infectiology, Helios Clinic, Schwerin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"German IBD Study Group (GISG) KND","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,4,9]]},"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0838-6371.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T22:50:27Z","timestamp":1554850227000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0838-6371"}},"subtitle":["Psychosocial impairments in IBD: Data from a national German multicenter cohort"],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":0,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2019,4,9]]},"published-print":{"date-parts":[[2019,4]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0838-6371","relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"type":"print","value":"0044-2771"},{"type":"electronic","value":"1439-7803"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}