{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:22:45Z","timestamp":1759335765653},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Two intact bitches aged 9 and 11\u2005years were referred due to chronic polyuria,\n                    polydipsia, vomiting, anorexia and progressive lethargy. On clinical\n                    examination, signs of tissue overgrowth (large paws, widened interdental space,\n                    pharyngeal stridor) were noticed. Diabetes mellitus (DM) was diagnosed in one\n                    dog (case 1) and diabetic ketoacidosis (DKA) in the other (case 2). There were\n                    increased IGF-1 values suggestive of hypersomatotropism. Progesterone values and\n                    pathological findings of the ovaries and uterus indicated diestrus. Diagnosis of\n                    diestrus-induced hypersomatotropism was made and ovariohysterectomy was\n                    performed in both dogs. Dog 1 also had multiple mammary neoplasms treated with\n                    bilateral mastectomy. Treatment resulted in diabetic remission in case 1 and\n                    improved glycaemic control in case 2.\u2005Overall, diestrus-induced\n                    hypersomatotropism is rare but should be considered in any intact diabetic bitch\n                    with acromegalic features. Ovariohysterectomy is recommended and associated with\n                    a fair to good prognosis.<\/jats:p>","DOI":"10.1055\/a-0886-9360","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T22:36:26Z","timestamp":1560897386000},"page":"193-201","source":"Crossref","is-referenced-by-count":1,"title":["Clinical diabetes mellitus in association with\n                    diestrus-induced acromegaly in 2 bitches"],"prefix":"10.1055","volume":"47","author":[{"given":"Yi","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Small Animal Internal\n                    Medicine, Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natali","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Small Animal Internal\n                    Medicine, Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Hausmann","sequence":"additional","affiliation":[{"name":"Tierklinik Elversberg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjam","family":"Wei\u00df","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Small Animal Internal\n                    Medicine, Justus-Liebig-Universit\u00e4t Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarina","family":"Hazuchova","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services, Royal Veterinary College,\n                    University of London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,6,18]]},"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0886-9360.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T22:36:29Z","timestamp":1560897389000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0886-9360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2019,6,18]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0886-9360","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}