{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T02:17:46Z","timestamp":1789265866032,"version":"build-2803163510"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We studied the effects of supramaximal interval exercise (SIE) with or without antihypertensive medication (AHM) on 21-hr blood pressure (BP) response. Twelve hypertensive patients chronically medicated with AHM, underwent three trials in a randomized order: a) control trial without exercise and substituting their AHM with a placebo (PLAC); b) placebo medicine and a morning bout of SIE (PLAC+SIE), and c) combining AHM and exercise (AHM+SIE). Acute and ambulatory blood pressure responses were measured for 21-hr after treatment. 20 \u2009min after treatment, systolic blood pressure (SBP) readings were reduced, similar to readings after PLAC+SIE (\u22129.7\u00b16.0\u2009mmHg, P&lt;0.001) and AHM+SIE (\u221210.4\u00b17.9\u2009mmHg, P=0.001). 21\u2009h after treatment, SBP remained reduced after PLAC+SIE (125\u00b112\u2009mmHg, P=0.022) and AHM+SIE (122\u00b112\u2009mmHg, P=0.013) compared to PLAC (132\u00b116\u2009mmHg). The BP reduction in PLAC+SIE faded out at 4 a.m., while in AHM+SIE it continued overnight. At night, BP reduction was larger in AHM+SIE than PLAC+SIE (\u20135.6\u00b14.0\u2009mmHg, P=0.006). Our data shows that a bout of supramaximal aerobic interval exercise in combination with ARB medication in the morning elicits a sustained blood pressure reduction lasting at least 21-h. Thus, the combination of exercise and angiotensin receptor blocker medication seems superior to exercise alone for acutely decreasing blood pressure.<\/jats:p>","DOI":"10.1055\/a-0927-6957","type":"journal-article","created":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T23:17:40Z","timestamp":1567466260000},"page":"756-761","source":"Crossref","is-referenced-by-count":9,"title":["Post-exercise Hypotension Produced by Supramaximal Interval Exercise is Potentiated by Angiotensin Receptor Blockers"],"prefix":"10.1055","volume":"40","author":[{"given":"Miguel","family":"Ramirez-Jimenez","sequence":"additional","affiliation":[{"name":"Exercise Physiology Lab, Universidad de Castilla-La Mancha, Toledo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Morales-Palomo","sequence":"additional","affiliation":[{"name":"Exercise Physiology Lab, Universidad de Castilla-La Mancha, Toledo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Fernando","family":"Ortega","sequence":"additional","affiliation":[{"name":"Exercise Physiology Lab, Universidad de Castilla-La Mancha, Toledo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Mora-Rodriguez","sequence":"additional","affiliation":[{"name":"Exercise Physiology Lab, Universidad de Castilla-La Mancha, Toledo, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,9,2]]},"container-title":["International Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0927-6957.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T23:31:18Z","timestamp":1572651078000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0927-6957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,2]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,11,1]]},"published-print":{"date-parts":[[2019,11]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0927-6957","relation":{},"ISSN":["0172-4622","1439-3964"],"issn-type":[{"value":"0172-4622","type":"print"},{"value":"1439-3964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,2]]}}}