{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:03:09Z","timestamp":1782298989136,"version":"3.54.5"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"08","license":[{"start":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T00:00:00Z","timestamp":1565222400000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002There are limited published data on endoscopic removal of colorectal polyps by endoscopic mucosal resection (EMR) and endoscopic mucosal dissection (ESD) in patients with inflammatory bowel disease (IBD). <\/jats:p><jats:p>\n          Patients and methods\u2002We performed a retrospective review of patients with colonic IBD and colonic polyps &gt;10mm who underwent EMR and\/or ESD at our institution between January 1, 2012 and June 31, 2016. <\/jats:p><jats:p>\n          Results\u2002Ninety-seven patients with pathology-confirmed IBD (median disease duration 16 years) were included. Mild or moderate active colitis (in background biopsies) was seen in 85\u200a%. Of the total 124 polyps, location was ascending colon in 44\u200a%, transverse in 15\u200a% and sigmoid in 18.5\u200a%; of the total, 55\u200a% were &lt;\u200a20\u200amm and 45\u200a% were \u226520mm in maximal diameter. Using the Paris classification, 56\u200a% of polyps were polypoid sessile (Is) polyps, while 38\u200a% were non-polypoid (IIa, IIb, IIc). EMR was used in 118 polyps, three required ESD, and three by combined EMR-ESD. Seventy-two percent were resected en-bloc; 28\u200a% underwent piecemeal resection. Histology included low-grade dysplasia in 75, serrated adenoma in 31, and tubular adenoma in 14 polyps. Chromoendoscopy was used in 33 (26.6\u200a%). Adverse events occurred in three patients. Colectomy was performed in 11 patients within 12 months. Recurrence was seen in 20 polyps, 11 of which were successfully resected en-bloc using EMR. Polyps \u2265\u200a20\u200amm and polyps treated with APC were found to have a statistically significantly higher risk of recurrence.<\/jats:p><jats:p>\n          Conclusion\u2002This study demonstrates the efficacy and safety of endoscopic resection of large polyps in patients with IBD, making them effective alternatives to colectomy.<\/jats:p>","DOI":"10.1055\/a-0953-2021","type":"journal-article","created":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T18:44:57Z","timestamp":1565289897000},"page":"E994-E1001","source":"Crossref","is-referenced-by-count":24,"title":["Outcome of endoscopic resection of colonic polyps larger than 10\u200amm in patients with inflammatory bowel disease"],"prefix":"10.1055","volume":"07","author":[{"given":"Siddhant","family":"Yadav","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Minnesota, United States"},{"name":"Division of Internal Medicine, Hennepin County Medical Center, Minneapolis, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Edward V.","family":"Loftus","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Scott","family":"Harmsen","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics, Mayo Clinic Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis M.","family":"Wong Kee Song","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayantara","family":"Coelho-Prabhu","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,8,8]]},"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0953-2021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T18:44:57Z","timestamp":1565289897000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0953-2021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2019,7,24]]},"published-print":{"date-parts":[[2019,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0953-2021","relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8]]}}}