{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:16:59Z","timestamp":1793222219587,"version":"4.5.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"11","license":[{"start":{"date-parts":[[2019,10,22]],"date-time":"2019-10-22T00:00:00Z","timestamp":1571702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002Endoscopic negative pressure therapy (ENPT) is used to close transmural defects in the rectum and esophagus. Very few reports have described ENPT to manage duodenal defects. This study was designed to demonstrate ENPT in a population of 11 patients with transmural duodenal leakages.<\/jats:p><jats:p>\n          Patients and methods\u2002The method of ENPT was adapted for duodenal use. Open-pore polyurethane-foam or a thin, open-pore double-layered film was wrapped around the distal end of a gastroduodenal tube. First, this open-pore element was placed on the inner wound in the duodenum with endoscopy. Second, continuous negative pressure of \u2013125\u200ammHg was applied with an electronic pump.\u200aDrains were changed after 2 to 7 days.<\/jats:p><jats:p>\n          Results\u2002Eleven patients were treated with duodenal leaks. Eight defects occurred after operative closure of perforated duodenal ulcers, papillectomy or stricturoplasty, one anastomotic leakage after Billroth \u2013 1 distal gastric resection, one iatrogenic perforation in endoscopic retrograde cholangiopancreatography, and one by a surgical drain. Median duration of therapy was 11 days (range 7\u200a\u2013\u200a24 days). Complete healing of defects was achieved in all patients.<\/jats:p><jats:p>\n          Conclusion\u2002ENPT is an innovative endoscopic alternative for treatment of transmural duodenal defects.<\/jats:p>","DOI":"10.1055\/a-0972-9660","type":"journal-article","created":{"date-parts":[[2019,10,22]],"date-time":"2019-10-22T22:31:04Z","timestamp":1571783464000},"page":"E1424-E1431","source":"Crossref","is-referenced-by-count":30,"title":["Endoscopic negative pressure therapy (ENPT) for duodenal leakage \u2013 novel repair technique using open-pore film (OFD) and polyurethane-foam drainages (OPD)"],"prefix":"10.1055","volume":"07","author":[{"given":"Gunnar","family":"Loske","sequence":"additional","affiliation":[{"name":"Marienkrankenhaus - Department for General, Abdominal, Thoracic and Vascular Surgery, Hamburg, Germany, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Rucktaeschel","sequence":"additional","affiliation":[{"name":"Westk\u00fcstenklinikum Heide - Department for Internal Medicine, Gastroenterology, Hemato-Oncology, Nephrology and Endocrinology, Heide, Schleswig-Holstein, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schorsch","sequence":"additional","affiliation":[{"name":"Marienkrankenhaus - Department for General, Abdominal, Thoracic and Vascular Surgery, Hamburg, Germany, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Moenkemueller","sequence":"additional","affiliation":[{"name":"HELIOS Frankenwaldklinik Kronach - Department of GastroenterologyKronach, Bayern, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Theodor","family":"Mueller","sequence":"additional","affiliation":[{"name":"Marienkrankenhaus - Department for General, Abdominal, Thoracic and Vascular Surgery, Hamburg, Germany, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,10,22]]},"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-0972-9660.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,22]],"date-time":"2019-10-22T22:31:14Z","timestamp":1571783474000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-0972-9660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,22]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019,10,22]]},"published-print":{"date-parts":[[2019,11]]}},"URL":"https:\/\/doi.org\/10.1055\/a-0972-9660","relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,22]]}}}