{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:52:05Z","timestamp":1791816725113,"version":"4.3.4"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund Retinale arterielle Verschl\u00fcsse (RAO) werden durch embolische Verschl\u00fcsse der retinalen Arterien verursacht. Ein Schlaganfall in der Anamnese wird bei bis zu 20% der Patienten beschrieben. In einer Blutflusssimulation anhand einer Magnetresonanztomografieaufnahme eines Patienten mit RAO gingen 90% der aszendierenden Emboli mit dem Blutstrom in die Hirnarterien. Andere embolische Quellen, wie arterielle Plaques in der A.\u00a0ophthalmica, kommen daher auch als m\u00f6gliche Ursachen f\u00fcr RAO infrage. Ziel der Studie war, Kaliberreduktionen der A.\u00a0ophthalmica in der Magnetresonanzangiografie (MRA) zu untersuchen.<\/jats:p><jats:p>\n          Patienten und Methoden Eine prospektive Fallserie von 9\u00a0Patienten mit neu diagnostizierter RAO, die in der Ambulanz erstvorgestellt wurden. Eine MRA des Gehirns mit Einschluss der A.\u00a0ophthalmica und des Karotissiphons wurde bei allen Patienten durchgef\u00fchrt und von einem erfahrenen Neuroradiologen beurteilt.<\/jats:p><jats:p>\n          Ergebnisse Vier von 9 Patienten (44,4%) hatten eine Kaliberreduktion in der A.\u00a0ophthalmica, 2 nur auf der Seite der RAO und die anderen 2 bilateral. Einer dieser Patienten hatte auch eine hochgradige Karotisstenose, die sowohl in der MRA als auch Karotissonografie gezeigt werden konnte. In der Kontrollgruppe wurden keine Kaliberreduktionen der A.\u00a0ophthalmica diagnostiziert.<\/jats:p><jats:p>\n          Schlussfolgerung Kaliberreduktionen der A.\u00a0ophthalmica sind in der MRA bei etwa der H\u00e4lfte der Patienten mit RAO diagnostizierbar und weisen auf stenookklusive Ver\u00e4nderungen der A.\u00a0ophthalmica als m\u00f6gliche Thrombosequelle f\u00fcr RAO hin.<\/jats:p>","DOI":"10.1055\/a-0972-9886","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T23:14:22Z","timestamp":1572045262000},"page":"972-975","source":"Crossref","is-referenced-by-count":1,"title":["Kaliberreduktion der A.\u00a0ophthalmica in der Magnetresonanzangiografie bei Patienten nach retinalen arteriellen Verschl\u00fcssen"],"prefix":"10.1055","volume":"237","author":[{"given":"Christoph","family":"Leisser","sequence":"additional","affiliation":[{"name":"Vienna Institute of Research in Ocular Surgery, Hanusch-Krankenhaus, Wien, \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahin","family":"Zandieh","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr Radiologie und Nuklearmedizin, Hanusch-Krankenhaus, Wien, \u00d6sterreich"},{"name":"Abteilung f\u00fcr Radiologie, Paracelsus Medizinische Privatuniversit\u00e4t, Salzburg, \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nino","family":"Hirnschall","sequence":"additional","affiliation":[{"name":"Vienna Institute of Research in Ocular Surgery, Hanusch-Krankenhaus, Wien, \u00d6sterreich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Findl","sequence":"additional","affiliation":[{"name":"Vienna Institute of Research in Ocular Surgery, Hanusch-Krankenhaus, Wien, 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Hayreh","year":"2009","journal-title":"Ophthalmology"},{"key":"ref4","first-page":"595","article-title":"Systemic diseases in non-inflammatory branch and central retinal artery occlusion \u2013 an overview of 416 patients","volume":"12","author":"D Schmidt","year":"2007","journal-title":"Eur J Med Res"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/j.jvs.2007.07.054","article-title":"The fate of patients with retinal artery occlusion and Hollenhorst plaque","volume":"46","author":"A B Dunlap","year":"2007","journal-title":"J Vasc Surg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/s00717-014-0218-5","article-title":"Risk factor analysis in patients with retinal artery occlusion with respect to transesophageal echocardiography","volume":"28","author":"C Leisser","year":"2014","journal-title":"Spektrum Augenheilkd"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0002-9394(02)01471-X","article-title":"The role of hyperhomocysteinemia and methylentetrahydrofolate reductase (MTHFR) C677T mutation in patients with retinal artery occlusion","volume":"134","author":"M Weger","year":"2002","journal-title":"Am J Ophthalmol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.ophtha.2004.10.039","article-title":"Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health Studies","volume":"112","author":"T Y Wong","year":"2005","journal-title":"Ophthalmology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1161\/01.STR.0000226929.23297.75","article-title":"Retinal arteriolar emboli and long-term mortality: pooled data analysis from two older populations","volume":"37","author":"J J Wang","year":"2006","journal-title":"Stroke"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s00417-014-2804-2","article-title":"Distribution of internal carotid artery plaque locations among patients with central retinal artery occlusion in the Eagle study population","volume":"253","author":"C Leisser","year":"2015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"ref11","first-page":"108","article-title":"Retinal ischemia and embolism. 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