{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:41:19Z","timestamp":1790786479196,"version":"4.1.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Padiatr"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background Physiotherapy, including vibration-assisted therapy, has\n                        been proven to be effective for patients with ataxic cerebral palsy.\n                        Herewith, we studied the effect of a functional, goal-oriented interval\n                        rehabilitation program, including vibration-assisted home-training on the\n                        motor function of children with congenital ataxias.<\/jats:p><jats:p>\n          Patients 45 children (mean age 7.7 years, SD 4.70) with ataxia, having\n                        received a 6-month home-based side-alternating vibration-assisted therapy\n                        combined with intensive, goal-oriented, functional rehabilitation intervals,\n                        were included in the study, classified according to the progressive or\n                        non-progressive ataxia character.<\/jats:p><jats:p>\n          Method Retrospective analysis of the prospectively collected data of\n                        the registry of the Cologne rehabilitation program \u201cAuf die\n                        Beine\u201d. Motor abilities have been assessed prior to the intervention\n                        (M0), after 6 months of home-training (M6) as well as in a follow-up 6\n                        months later (M12). We performed a gait analysis, a 1-minute walking test\n                        (1-MWT), and the Gross Motor Function Measure (GMFM-66).<\/jats:p><jats:p>\n          Results The GMFM-66 improvement (M6\u2013M0 vs. M12\u2013M6) was\n                        statistically significant with median improvement of 2.4 points\n                        (non-progressive) and 2.9 points (progressive) respectively, and clinically\n                        relevant. The 1-MWT improvement was statistically significant and clinically\n                        relevant for non-progressive ataxia.<\/jats:p><jats:p>\n          Conclusion The intensive training, including vibration-assisted\n                        therapy significantly improved the motor function of children with ataxia.\n                        Six months later the skills were preserved in children with progressive\n                        ataxia and could be further developed in non-progressive forms.<\/jats:p>","DOI":"10.1055\/a-1001-2284","type":"journal-article","created":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T20:50:50Z","timestamp":1573678250000},"page":"304-312","source":"Crossref","is-referenced-by-count":8,"title":["Motor Function Improvement in Children with Ataxia Receiving Interval\n                    Rehabilitation, Including Vibration-Assisted Hometraining: A Retrospective\n                    Study"],"prefix":"10.1055","volume":"231","author":[{"given":"Kyriakos","family":"Martakis","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Department of Pediatrics, Cologne, Germany"},{"name":"CAPHRI\u2014School of Public Health and Primary Care, Faculty of\n                    Health, Medicine, and Life Sciences, Maastricht University, Department of\n                    International Health, Maastricht, Netherlands"},{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Center for Prevention and Rehabilitation, UniReha GmbH, Cologne,\n                    Germany"},{"name":"Department of Pediatric Neurology, University Children\u2019s\n                    Hospital (UKGM) and Medical Faculty, Justus Liebig University of Giessen,\n                    Giessen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Stark","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Department of Pediatrics, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Alberg","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Center for Prevention and Rehabilitation, UniReha GmbH, Cologne,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Bossier","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Center for Prevention and Rehabilitation, UniReha GmbH, Cologne,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Semler","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Department of Pediatrics, Cologne, Germany"},{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Center for Prevention and Rehabilitation, UniReha GmbH, Cologne,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eckhard","family":"Sch\u00f6nau","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Department of Pediatrics, Cologne, Germany"},{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Center for Prevention and Rehabilitation, UniReha GmbH, Cologne,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Duran","sequence":"additional","affiliation":[{"name":"University of Cologne, Faculty of Medicine and University Hospital\n                    Cologne, Center for Prevention and Rehabilitation, UniReha GmbH, Cologne,\n                    Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,11,13]]},"container-title":["Klinische P\u00e4diatrie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1001-2284.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,13]],"date-time":"2019-11-13T20:50:52Z","timestamp":1573678252000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1001-2284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,11,13]]},"published-print":{"date-parts":[[2019,11]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1001-2284","relation":{},"ISSN":["0300-8630","1439-3824"],"issn-type":[{"value":"0300-8630","type":"print"},{"value":"1439-3824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]}}}