{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:46:51Z","timestamp":1784810811738,"version":"3.55.0"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose\u2002ElastPQ is a new elastography technique for non-invasive liver fibrosis staging. However, it does not have validated reliability criteria. We tested the reliability of a different number of measurements in patients with chronic liver disease and explored whether the application of quality criteria improves the diagnostic performance.<\/jats:p><jats:p>\n          Materials and Methods\u2002All patients underwent liver stiffness assessment (LSM) with ElastPQ and Fibroscan (F-TE). The mean, median, standard deviation (SD) and interquartile range (IQR) of 10, 5 and 3 measurements were retrospectively collected for each patient and compared to each other. Liver histology was available in a subset of patients.<\/jats:p><jats:p>\n          Results\u2002Overall, 400 patients met the inclusion criteria. Non-alcoholic fatty liver disease (NAFLD) was the most represented etiology (75\u200a%), followed by primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH). The correlation of medians was significantly better between 10 and 5 measurements than between 10\u00a0and 3. The difference of medians was significant only in the comparison between 10 and 3 measurements. The correlation between ElastPQ and F-TE was equally good for 10 and 5\u00a0measurements and significantly improved after an IQR\/median \u2264\u200a30\u200a% was applied. The diagnostic performance of ElastPQ was better with the median value of 10 and 5 measurements and improved if LSM values were obtained with IQR\/M\u200a\u2264\u200a30\u200a%.<\/jats:p><jats:p>\n          Conclusion\u2002The median value of 5 valid LSMs suffices for the reliable estimation of liver stiffness using ElastPQ. The quality criterion of IQR\/M\u200a\u2264\u200a30\u200a% should also be followed when using this technique.<\/jats:p>","DOI":"10.1055\/a-1010-6052","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T22:47:12Z","timestamp":1570574832000},"page":"204-213","source":"Crossref","is-referenced-by-count":16,"title":["Establishing Reliability Criteria for Liver ElastPQ Shear Wave Elastography (ElastPQ-SWE): Comparison Between 10, 5 and 3 Measurements"],"prefix":"10.1055","volume":"42","author":[{"given":"Davide","family":"Roccarina","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Iogna Prat","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Buzzetti","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Guerrero Misas","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Marcello","family":"Aric\u00f3","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University-Hospital and School of Medicine of Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Saffioti","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"},{"name":"Department of Clinical and Experimental Medicine, University-Hospital and School of Medicine of Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Rosselli","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Pinzani","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aileen","family":"Marshall","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Thorburn","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Tsochatzis","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health and Sheila Sherlock Liver Unit, Royal Free Hospital and UCL, London, United Kingdom of Great Britain and Northern Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,10,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/hep.1840200104","article-title":"Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C","volume":"20","author":"The French METAVIR Cooperative Study Group","year":"1994","journal-title":"Hepatology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.7863\/jum.2010.29.11.1581","article-title":"Evaluation of sound speed for detection of liver fibrosis: prospective comparison with transient dynamic elastography and histology","volume":"29","author":"B Boozari","year":"2010","journal-title":"J Ultrasound Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.jhep.2013.12.023","article-title":"Collagen proportionate area is superior to other histological methods for 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Boursier","year":"2014","journal-title":"J Gastroenterol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.jhep.2014.04.045","article-title":"Steatosis affects the performance of liver stiffness measurement for fibrosis assessment in patients with genotype 1 chronic hepatitis C","volume":"61","author":"F S Macaluso","year":"2014","journal-title":"J Hepatol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1111\/jgh.12519","article-title":"Controlled attenuation parameter for the detection of steatosis severity in chronic liver disease: a meta-analysis of diagnostic accuracy","volume":"29","author":"K Q Shi","year":"2014","journal-title":"J Gastroenterol Hepatol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/hep.28843","article-title":"Improved noninvasive prediction of liver fibrosis by liver stiffness measurement in patients with nonalcoholic fatty liver disease accounting for controlled attenuation parameter values","volume":"65","author":"S Petta","year":"2017","journal-title":"Hepatology"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1111\/j.1365-2036.2011.04668.x","article-title":"Reliability of liver stiffness measurement in non-alcoholic fatty liver disease: the effects of body mass index","volume":"33","author":"S Petta","year":"2011","journal-title":"Aliment Pharmacol Ther"}],"container-title":["Ultraschall in der Medizin - European Journal of 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