{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:11:34Z","timestamp":1784308294152,"version":"3.55.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 9-year-old female neutered domestic shorthair cat diagnosed with immune-mediated thrombocytopenia that was treated with\n                    prednisolone and cyclosporine, was presented for anorexia, vomiting, increased liver enzymes, and hyperbilirubinemia.\n                    Abdominal ultrasound revealed a markedly thickened gallbladder and common bile duct wall. Bile cytology detected severe\n                    neutrophilic inflammation and protozoal zoites. Suspected Toxoplasma gondii infection was confirmed by real-time\n                    PCR of bile. The cat was treated with clindamycin and ursodeoxycholic acid for 6 weeks, recovered and remained stable\n                    for 2 years despite ongoing immunosuppressive treatment. Thereafter, the cat was presented with suspicion of intestinal\n                    lymphoma, and recurrence of toxoplasmosis was diagnosed. Following treatment with clindamycin and prednisolone over 4\n                    weeks the cat was euthanized. This is the first report of Toxoplasma gondii zoites detected in bile fluid from a\n                    cat with cholecystitis. Pathogenesis of toxoplasmosis in cats is still not fully understood. Although immunosuppression\n                    can represent a relevant predisposing factor, other factors, such as virulence of the parasite and genetic polymorphism\n                    of the host, can also play an important role. Toxoplasmosis should be included as a differential diagnosis in cats\n                    developing clinical signs of an inflammatory disease while receiving immunosuppressive treatment.<\/jats:p>","DOI":"10.1055\/a-1020-3775","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T23:48:14Z","timestamp":1575676094000},"page":"453-457","source":"Crossref","is-referenced-by-count":12,"title":["Toxoplasma gondii-associated cholecystitis in a cat receiving immunosuppressive\n                    treatment"],"prefix":"10.1055","volume":"47","author":[{"given":"Francesco","family":"Lo Piccolo","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine,\n                    Ludwig Maximilian University of Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Busch","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine,\n                    Ludwig Maximilian University of Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Pali\u0107","sequence":"additional","affiliation":[{"name":"Vet Med Labor GmbH Division of IDEXX Laboratories"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Geisen","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine,\n                    Ludwig Maximilian University of Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine,\n                    Ludwig Maximilian University of Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Unterer","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, Faculty of Veterinary Medicine,\n                    Ludwig Maximilian University of Munich"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,12,6]]},"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1020-3775.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T23:48:19Z","timestamp":1575676099000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1020-3775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,12,6]]},"published-print":{"date-parts":[[2019,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1020-3775","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]}}}