{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T19:15:26Z","timestamp":1773602126071,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Sports Med"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Subconcussive head impacts (SHI), defined as impacts to the cranium that do not\n                    result in concussion symptoms, are gaining traction as a major public health\n                    concern. The contribution of physiological factors such as physical exertion and\n                    muscle damage to SHI-dependent changes in neurological measures remains unknown.\n                    A prospective longitudinal study examined the association between physiological\n                    factors and SHI kinematics in 15 high school American football players over one\n                    season. Players wore a sensor-installed mouthguard for all practices and games,\n                    recording frequency and magnitude of all head impacts. Serum samples were\n                    collected at 12 time points (pre-season, pre- and post-game for five in-season\n                    games, and post-season) and were assessed for an isoenzyme of creatine kinase\n                    (CK-MM) primarily found in skeletal muscle. Physical exertion was estimated in\n                    the form of excess post-exercise oxygen consumption (EPOC) from heart rate data\n                    captured during the five games. Mixed-effect regression models indicated that\n                    head impact kinematics were significantly and positively associated with change\n                    in CK-MM but not EPOC. There was a significant and positive association between\n                    CK-MM and EPOC. These data suggest that when examining SHI, effects of skeletal\n                    muscle damage should be considered when using outcome measures that may have an\n                    interaction with muscle damage.<\/jats:p>","DOI":"10.1055\/a-1021-1735","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T23:50:36Z","timestamp":1574293836000},"page":"36-43","source":"Crossref","is-referenced-by-count":3,"title":["Association between Muscle Damage and Head Impacts in High School\n                    American Football"],"prefix":"10.1055","volume":"41","author":[{"given":"Megan E.","family":"Huibregtse","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, Indiana University Bloomington, Bloomington,\n                    United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven W.","family":"Zonner","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Washington Township Medical Foundation,\n                    Union City, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Ejima","sequence":"additional","affiliation":[{"name":"Departments of Epidemiology and Biostatistics, Indiana University\n                    Bloomington, Bloomington, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary W.","family":"Bevilacqua","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, Indiana University Bloomington, Bloomington,\n                    United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharlene D.","family":"Newman","sequence":"additional","affiliation":[{"name":"Departments of Psychological & Brain Sciences, Indiana\n                    University Bloomington, Bloomington, United States"},{"name":"Program in Neuroscience, Indiana University Bloomington, Bloomington,\n                    United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan T.","family":"Macy","sequence":"additional","affiliation":[{"name":"Department of Applied Health Science, Indiana University Bloomington,\n                    Bloomington, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Kawata","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, Indiana University Bloomington, Bloomington,\n                    United States"},{"name":"Program in Neuroscience, Indiana University Bloomington, Bloomington,\n                    United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,11,20]]},"container-title":["International Journal of Sports Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1021-1735.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T23:31:15Z","timestamp":1578267075000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1021-1735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,20]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2020,1,5]]},"published-print":{"date-parts":[[2020,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1021-1735","relation":{},"ISSN":["0172-4622","1439-3964"],"issn-type":[{"value":"0172-4622","type":"print"},{"value":"1439-3964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,20]]}}}