{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T04:17:17Z","timestamp":1782965837622,"version":"3.54.5"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund und Zielsetzung\u2002Die radikale Zystektomie (RCX) ist die kurative Standardbehandlung f\u00fcr muskelinvasive Harnblasenkarzinome. Aufgrund des operativen Ausma\u00dfes und der damit verbundenen komplexen station\u00e4ren Betreuung ist die RCX mit hoher Morbidit\u00e4t und Mortalit\u00e4t verbunden. Ziel war es, Daten aus dem klinischen Alltag zur gegenw\u00e4rtigen Praxis des perioperativen Managements zu erfassen.<\/jats:p><jats:p>\n          Methoden\u2002Mitglieder der DGU und der German Society of Residents in Urology beantworteten anonym einen 24 Fragen umfassenden Online-Fragebogen. Gegenstand waren sowohl klinisch relevante Aspekte der gegenw\u00e4rtigen EAU\/DGU-Leitlinien als auch kontrovers diskutierte klinische Fragen.<\/jats:p><jats:p>\n          Ergebnisse\u2002Durch die Teilnehmer konnten mindestens 19\u200a% aller infrage kommenden deutschen Zentren erfasst werden. Mehrheitlich wird das pr\u00e4operative Staging mittels CT-Urografie und CT-Thorax durchgef\u00fchrt. Die meistgenutzte Antibiotikaprophylaxe umfasst ein Drittgenerations-Cephalosporin plus Metronidazol (46\u200a%), welche im Median f\u00fcr 5 Tage verabreicht werden. Harnleiterschienen (HS) werden im Mittel beim Ileumconduit am 11. und bei der Neoblase am 12.\u200aTag nach RCX entfernt. Gemessen an Surrogatparametern wie oraler Darmvorbereitung, Beginn des Kostaufbaus und Einsatz einer Magensonde sind aktuelle Fast-Track-Konzepte noch nicht allgemein verbreitet (&lt;\u200a50\u200a%).<\/jats:p><jats:p>\n          Schlussfolgerungen\u2002Die meisten Aspekte des perioperativen Managements werden leitliniengerecht durchgef\u00fchrt, so z.\u200aB. Staging-Untersuchungen, Einsatz von Antibiotika und Entfernung der HS. Andere klinische Fragestellungen wie Durchf\u00fchrung einer Bildgebung vor Entfernung der HS und Fast-Track-Konzepte werden unterschiedlich gehandhabt, obwohl zunehmende Evidenz in diesen Bereichen existiert. Leitlinienadh\u00e4renz war nicht mit Zentrumsgr\u00f6\u00dfe oder Anzahl der Eingriffe assoziiert. <\/jats:p>","DOI":"10.1055\/a-1025-2523","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T22:51:37Z","timestamp":1596063097000},"page":"82-87","source":"Crossref","is-referenced-by-count":2,"title":["Sicher zwischen Leitlinie und Leitplanke: Umfrage zur Praxis des perioperativen Managements der radikalen Zystektomie in Deutschland"],"prefix":"10.1055","volume":"52","author":[{"given":"Franz F.","family":"Dressler","sequence":"additional","affiliation":[{"name":"Universit\u00e4t zu L\u00fcbeck Sektion Medizin, Pathologie, L\u00fcbeck"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serkan","family":"Dogan","sequence":"additional","affiliation":[{"name":"Heilig Geist-Krankenhaus K\u00f6ln, Urologie, 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K\u00f6ln"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik","family":"Borgmann","sequence":"additional","affiliation":[{"name":"Johannes Gutenberg Universit\u00e4t Universit\u00e4tsmedizin, Klinik und Poliklinik f\u00fcr Urologie, Mainz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Klatte","sequence":"additional","affiliation":[{"name":"Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Urology, Bournemouth, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario W.","family":"Kramer","sequence":"additional","affiliation":[{"name":"Universit\u00e4t zu L\u00fcbeck Sektion Medizin, Urologie, L\u00fcbeck"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Hofbauer","sequence":"additional","affiliation":[{"name":"Charit\u00e9 Universit\u00e4tsmedizin Berlin, Urologie, 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