{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T22:34:08Z","timestamp":1702938848366},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Gem\u00e4\u00df einer aktuellen Metaanalyse zeigt in Europa jeder zweite Patient mit einem Peniskarzinom (PeK) eine Assoziation mit dem Humanen Papillomavirus (HPV). Es liegen keine Daten dar\u00fcber vor, inwieweit UrologInnen die H\u00e4ufigkeit dieser viralen Karzinogenese kennen.<\/jats:p><jats:p>\n          Methoden\u2002Es wurde ein 14-Items umfassender deutschsprachiger Survey erstellt und in Q3\/2018 einmalig an UrologInnen von 45 Kliniken in Deutschland (n\u200a=\u200a34), \u00d6sterreich (n\u200a=\u200a8), der Schweiz (n\u200a=\u200a2) und Italien\/S\u00fcdtirol (n\u200a=\u200a1) verschickt. Insgesamt waren nach vorher definiertem Qualit\u00e4tsstandard 557 Frageb\u00f6gen auswertbar (mediane R\u00fccklaufquote 85,7\u200a%). In dem Survey wurde u.\u200aa. nach der H\u00e4ufigkeit HPV-assoziierter PeK in Europa gefragt und 4 Antwortm\u00f6glichkeiten vorgegeben: (A)-\u201e&lt;\u200a25\u200a%\u201c, (B)-\u201e25\u200a\u2013\u200a50\u200a%\u201c, (C)-\u201e&gt;\u200a50\u200a\u2013\u200a75\u200a%\u201c, (D)-\u201ekein Wissen \u00fcber die H\u00e4ufigkeit des Zusammenhangs\u201c. Es wurde in der Auswertung eine Toleranz von 50\u200a% akzeptiert, sodass B und C (25\u200a\u2013\u200a75\u200a%) als korrekte Antworten gewertet wurden. Mittels eines Bootstrap-korrigierten multivariaten logistischen Regressionsmodells wurden Kriterien identifiziert, die unabh\u00e4ngig eine richtige Antwort der Befragten vorhersagten.<\/jats:p><jats:p>\n          Ergebnisse\u2002Die Kategorien A\u200a\u2013\u200aD wurden von 19,2\u200a% (n\u200a=\u200a107), 48,8\u200a% (n\u200a=\u200a272), 12,9\u200a% (n\u200a=\u200a72) bzw. 19\u200a% (n\u200a=\u200a106) als Antwort gew\u00e4hlt, sodass der Endpunkt von 61,8\u200a% (n\u200a=\u200a344) der UrologInnen erreicht wurde (B\u200a+\u200aC). Die selbstst\u00e4ndige Durchf\u00fchrung der Chemotherapie durch die Urologische Klinik (OR 1,55; p[Bootstrap]\u200a=\u200a0,036) und die Anzahl der urologischen Klinikbetten (OR 1,02; p[Bootstrap]\u200a=\u200a0,025) waren die einzigen Studienkriterien, die signifikant das richtige Ergebnis pr\u00e4dizierten. Der Status einer Universit\u00e4tsklinik (p\u200a=\u200a0,143), eine leitende Position der UrologInnen (p\u200a=\u200a0,375) bzw. die j\u00e4hrliche Anzahl behandelter PeK-Patienten (p\u200a=\u200a0,571) blieben hingegen ohne signifikanten Einfluss auf den Endpunkt.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Unsere Studienergebnisse zeigen, dass sich deutschsprachige Klinik-UrologInnen der H\u00e4ufigkeit einer gegenw\u00e4rtigen HPV-Assoziation des PeK nur unzureichend bewusst sind.<\/jats:p>","DOI":"10.1055\/a-1032-8086","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T10:06:35Z","timestamp":1574244395000},"page":"461-467","source":"Crossref","is-referenced-by-count":4,"title":["Kenntnisse von deutschsprachigen Urologen zur H\u00e4ufigkeit der Assoziation des Peniskarzinoms mit dem Humanen Papillomavirus \u2013 Survey-Ergebnisse der European PROspective Penile Cancer Study (E-PROPS)"],"prefix":"10.1055","volume":"53","author":[{"given":"Steffen","family":"Lebentrau","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Ruppiner Kliniken GmbH, Medizinische Hochschule Brandenburg Theodor Fontane, Neuruppin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingmar","family":"Wolff","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Urologie, Universit\u00e4tsmedizin Greifswald, Deutschland"},{"name":"Klinik f\u00fcr Urologie und Neuro-Urologie, Unfallkrankenhaus Berlin, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie Christine","family":"Hempel","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Universit\u00e4tsklinikum Schleswig-Holstein, Campus L\u00fcbeck, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlene","family":"Haccius","sequence":"additional","affiliation":[{"name":"Urologische Klinik, St. Elisabeth-Klinikum Straubing, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis A.","family":"Kluth","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Universit\u00e4tsklinik Frankfurt\/M., Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Pycha","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Klinikum Bozen, Italien"},{"name":"Sigmund Freud Private University, Medical School Vienna, \u00d6sterreich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Brookman-May","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Ludwigs-Maximilian-Universit\u00e4t M\u00fcnchen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Till Rasmus","family":"Schneider","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Universit\u00e4tsklinik G\u00f6ttingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hermanns","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Urologie, Universit\u00e4tsspital Z\u00fcrich, Universit\u00e4t Z\u00fcrich, Schweiz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian A.","family":"Distler","sequence":"additional","affiliation":[{"name":"Urologische Universit\u00e4tsklinik, Paracelsus Medizinische Privatuniversit\u00e4t am Klinikum N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Boegemann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Urologie und Kinderurologie, Universit\u00e4tsklinikum M\u00fcnster, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"K\u00fcbler","sequence":"additional","affiliation":[{"name":"Urologische Klinik, Universit\u00e4tsklinik W\u00fcrzburg, 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