{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T07:53:46Z","timestamp":1648799626339},"reference-count":5,"publisher":"Georg Thieme Verlag KG","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Was ist neu?<\/jats:title><jats:p>\n          Vortestwahrscheinlichkeit\u2002In den aktualisierten Leitlinien der Europ\u00e4ischen Gesellschaft f\u00fcr Kardiologie (European Society of Cardiology, ESC) wird die stabile koronare Herzkrankheit zum chronischen Koronarsyndrom (CCS) umbenannt. Unter CCS werden 6 verschiedene Szenarien definiert, die der Heterogenit\u00e4t Rechnung tragen. Die diagnostische Beurteilung der Vortestwahrscheinlichkeit spielt auch in der aktuellen Leitlinie bei m\u00f6glichem Vorliegen einer stenosierenden KHK eine wichtige Rolle. Die Hinzunahme von Dyspnoe und der klinischen Wahrscheinlichkeit als zus\u00e4tzliche Variablen zur besseren Absch\u00e4tzung der Vortestwahrscheinlichkeit sind 2 wichtige Neuerungen.<\/jats:p><jats:p>\n          Diagnostische Verfahren\u2002Bildgebende Verfahren wie die CT-Angiografie wurden als diagnostische Verfahren zur Detektion von KHK deutlich aufgewertet, w\u00e4hrend das Belastungs-EKG diesbez\u00fcglich nicht mehr routinem\u00e4\u00dfig empfohlen wird. Die invasive Koronarangiografie mit Revaskularisationsoption bleibt ein zentrales diagnostisches und therapeutisches Verfahren.<\/jats:p><jats:p>\n          Therapie\u2002Neben der antiangin\u00f6sen, lipidsenkenden und antithrombotischen Therapie wird in der aktuellen CCS-Leitlinie ein besonderes Augenmerk auf Pr\u00e4vention mittels Lebensstilmodifikation gelegt.<\/jats:p>","DOI":"10.1055\/a-1039-8764","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T22:40:46Z","timestamp":1602024046000},"page":"1476-1480","source":"Crossref","is-referenced-by-count":0,"title":["Chronisches Koronarsyndrom"],"prefix":"10.1055","volume":"145","author":[{"given":"Stanislav","family":"Keranov","sequence":"additional","affiliation":[{"name":"Medizinischen Klinik I, Innere Medizin\/Kardiologie, Universit\u00e4tsklinikum Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Nef","sequence":"additional","affiliation":[{"name":"Medizinischen Klinik I, Innere Medizin\/Kardiologie, Universit\u00e4tsklinikum Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,10,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s41569-019-0233-y","article-title":"The myth of \u201cstable\u201d coronary artery disease","volume":"17","author":"K AA Fox","year":"2020","journal-title":"Nat Rev Cardiol"},{"key":"ref2","first-page":"407","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"J Knuuti","year":"2020","journal-title":"Eur\u00a0Heart J"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"G Montalescot","year":"2013","journal-title":"Eur Heart J"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS Guidelines on myocardial revascularization","volume":"40","author":"F J Neumann","year":"2019","journal-title":"Eur Heart J"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/eurheartj\/ehz455","article-title":"2019 ESC\/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk","volume":"41","author":"F Mach","year":"2020","journal-title":"Eur Heart J"}],"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1039-8764.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T22:41:19Z","timestamp":1602024079000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1039-8764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":5,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2020,10,6]]},"published-print":{"date-parts":[[2020,10]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1039-8764","relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"value":"0012-0472","type":"print"},{"value":"1439-4413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10]]}}}