{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:22:35Z","timestamp":1778574155406,"version":"3.51.4"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n                    Background Heterotopic pregnancy refers to the simultaneous coexistence\n                    of an intrauterine and extrauterine pregnancy. In natural conception it is very\n                    rare, with a rising incidence in patients undergoing assisted reproduction\n                    technologies. It presents a serious diagnostic problem which is often\n                    misdiagnosed. Currently, there are no standard protocols for the treatment and\n                    diagnosis of heterotopic pregnancy.<\/jats:p><jats:p>\n                    Methods Two rare cases of spontaneous heterotopic pregnancy are\n                    presented.<\/jats:p><jats:p>\n                    Result The first patient had a complete abortion upon which an\n                    extrauterine pregnancy was detected. The second patient, after an extrauterine\n                    pregnancy removal, progressed with an intrauterine pregnancy until full term and\n                    it ended with the delivery of a healthy infant.<\/jats:p><jats:p>\n                    Conclusion Two demonstrated cases underscore that whenever abnormal\n                    adnexal findings are presented and the beta-hCG blood test is positive, the\n                    possibility of a heterotopic pregnancy should be suspected.<\/jats:p>","DOI":"10.1055\/a-1079-6260","type":"journal-article","created":{"date-parts":[[2020,3,6]],"date-time":"2020-03-06T23:50:15Z","timestamp":1583538615000},"page":"223-226","source":"Crossref","is-referenced-by-count":6,"title":["Spontaneous Heterotopic Pregnancy as an Uncommon Clinical\n                    Problem"],"prefix":"10.1055","volume":"224","author":[{"given":"Zana","family":"Stanic","sequence":"additional","affiliation":[{"name":"Obstetric and Gynecology Clinic, University Hospital Center Split\n                    Kri\u017eine, Split, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damir","family":"Roje","sequence":"additional","affiliation":[{"name":"Obstetric and Gynecology Clinic, University Hospital Center Split\n                    Kri\u017eine, Split, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Mati\u0107","sequence":"additional","affiliation":[{"name":"Surgery Clinic, University Hospital Center Split Kri\u017eine,\n                    Split, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoran","family":"Persec","sequence":"additional","affiliation":[{"name":"Urology Department, University Hospital Dubrava, Zagreb,\n                    Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kresimir","family":"Dapic","sequence":"additional","affiliation":[{"name":"Urology Department, University Hospital Dubrava, Zagreb,\n                    Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja Rogi\u0107","family":"Vidakovi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Laboratory for Human and Experimental\n                    Neurophysiology (LAHEN), Department of Neuroscience, University of Split, Split,\n                    Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajko","family":"Fure\u0161","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Zabok General Hospital, Zabok,\n                    Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zlatko","family":"Hrgovic","sequence":"additional","affiliation":[{"name":"Gynekology, J. W. Goethe University, Frankfurt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dora","family":"Fure\u0161","sequence":"additional","affiliation":[{"name":"University of Split Faculty of Medicine, Split, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,3,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jemermed.2015.02.050","article-title":"Spontaneous heterotopic pregnancy presenting with hemoperitoneum","volume":"50","author":"V Mihmanli","year":"2016","journal-title":"J Emerg Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.jogoh.2017.05.008","article-title":"Spontaneous heterotopic triplets \u2013 A review of literature","volume":"46","author":"P Bataille","year":"2017","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"728","DOI":"10.4103\/0972-5229.171407","article-title":"Hypovolemic shock following induced abortion and spontaneous heterotopic\n                    pregnancy","volume":"19","author":"A Pakniyat","year":"2015","journal-title":"Indian J Crit Care Med"},{"key":"ref4","first-page":"367","article-title":"Spontaneous heterotopic, ectopic cervical and tubal pregnancy \u2013 ever\n                    present difficuly: Three case reports","volume":"54","author":"I E Ivko\u0161i\u0107","year":"2015","journal-title":"Acta Clin Croat"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3109\/01443615.2013.769502","article-title":"Heterotopic pregnancy after spontaneous conception","volume":"33","author":"A Nargund","year":"2013","journal-title":"J Obstet Gynaecol"},{"key":"ref6","first-page":"252","article-title":"Spontaneous heterotopic pregnancy: A successful outcome","volume":"34","author":"A A Seoud","year":"2007","journal-title":"Clin Exp Obstet Gynecol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ijgo.2006.09.033","article-title":"Spontaneous heterotopic pregnancy and acute appendicitis treated by\n                    laparoscopy","volume":"96","author":"M Radwan","year":"2007","journal-title":"Int J Gynaecol Obstet"},{"key":"ref8","first-page":"2145937","article-title":"Spontaneous heterotopic pregnancy: Dual case report and review of\n                    literature","volume":"2016","author":"A Chadee","year":"2016","journal-title":"Case Rep Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.fertnstert.2018.11.042","article-title":"Robot-assisted orthotopic and heterotopic ovarian tissue transplantation\n                    techniques: Surgical advances since our first success in 2000","volume":"111","author":"K Oktay","year":"2019","journal-title":"Fertil Steril"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1080\/01443615.2018.1530972","article-title":"Successful laparoscopic treatment of asymptomatic heterotopic pregnancy after\n                    spontaneous conception","volume":"39","author":"N Nazl\u0131 Yenigul","year":"2019","journal-title":"J Obstet Gynaecol"}],"container-title":["Zeitschrift f\u00fcr Geburtshilfe und Neonatologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1079-6260.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T22:38:19Z","timestamp":1598308699000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1079-6260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,6]]},"references-count":10,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2020,8,24]]},"published-print":{"date-parts":[[2020,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1079-6260","relation":{},"ISSN":["0948-2393","1439-1651"],"issn-type":[{"value":"0948-2393","type":"print"},{"value":"1439-1651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,6]]}}}