{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T11:33:53Z","timestamp":1648985633974},"reference-count":48,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Zielsetzung In der Literatur werden verschiedene Formen der heredit\u00e4ren Polyposis beschrieben. Die klassische famili\u00e4re adenomat\u00f6se Polyposis (FAP) ist eine seltene, autosomal-dominant vererbte Erkrankung, die durch eine Keimbahnmutation im Adenomatous-Polyposis-coli-Gen (APC) verursacht wird und sich klinisch durch einen ausgedehnten Befall des Kolons mit multiplen Polypen charakterisiert. Unbehandelt f\u00fchrt die Erkrankung beinahe unweigerlich zur malignen Entartung.<\/jats:p><jats:p>\n          Indikation Wir pr\u00e4sentieren den Fall eines 37-j\u00e4hrigen Patienten mit histologisch gesichertem, stenosierendem Adenokarzinom des Colon descendens sowie initialem Verdacht auf eine heredit\u00e4re Polyposis bei multiplen Polypen im Colon descendens und sigmoideum.<\/jats:p><jats:p>\n          Methoden Das Video erl\u00e4utert die pr\u00e4operativen bildgebenden sowie endoskopischen Befunde und zeigt die Technik der zweizeitigen, roboterassistierten Proktokolektomie mit ileopouchanaler Anastomose (IPAA) und Anlage eines protektiven Loop-Ileostomas.<\/jats:p><jats:p>\n          Schlussfolgerung Hinsichtlich der chirurgischen Therapie der klassischen FAP kann die restaurative Proktokolektomie (RPC) mit Anlage eines Ileum-J-Pouches \u2013 trotz Kontroversen hinsichtlich verschiedener technischer Aspekte \u2013 als etabliertes Standardverfahren angesehen werden. Dabei sind die minimalinvasiven Strategien gegen\u00fcber den konventionellen Techniken als zumindest gleichwertig zu betrachten.<\/jats:p>","DOI":"10.1055\/a-1084-4159","type":"journal-article","created":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T23:48:46Z","timestamp":1580428126000},"page":"23-28","source":"Crossref","is-referenced-by-count":0,"title":["Roboterassistierte Proktokolektomie mit ileopouchanaler Anastomose bei Verdacht auf heredit\u00e4re Polyposis"],"prefix":"10.1055","volume":"146","author":[{"given":"Jens","family":"Rolinger","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Allgemeine, Viszeral- und Transplantationschirurgie, Universit\u00e4tsklinikum T\u00fcbingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Jansen","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Allgemeine, Viszeral- und Transplantationschirurgie, Universit\u00e4tsklinikum T\u00fcbingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"von Keller","sequence":"additional","affiliation":[{"name":"Facharzt f\u00fcr Gastroenterologie, Gastroenterologische Schwerpunktpraxis, T\u00fcbingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Axt","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Allgemeine, Viszeral- und Transplantationschirurgie, Universit\u00e4tsklinikum T\u00fcbingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudius","family":"Falch","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Allgemeine, Viszeral- und Transplantationschirurgie, Universit\u00e4tsklinikum T\u00fcbingen, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Kirschniak","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik 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