{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:51:08Z","timestamp":1792813868685,"version":"4.5.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p>Background\u2002Gastric peroral endoscopic pyloromyotomy (G-POEM) and gastric electrical stimulation (GES) have been reported as treatment options for refractory gastroparesis. In this study, we compared the long term clinical outcomes of G-POEM versus GES in the treatment of such patients.<\/jats:p>\n                  <jats:p>Methods\u2002We retrospectively evaluated 111 consecutive patients with refractory gastroparesis between January 2009 and August 2018. To overcome selection bias, we used propensity score matching (1:1) between G-POEM and GES treatment. The primary outcome was the duration of clinical response.<\/jats:p>\n                  <jats:p>Results\u2002After propensity score matching, 23 patients were included in each group.\u200aAfter a median follow-up of 27.7 months, G-POEM had a significantly better and longer clinical response than GES (hazard ratio [HR] for clinical recurrence 0.39, 95\u200a% confidence interval [CI] 0.16\u200a\u2013\u200a0.95; P\u200a=\u200a0.04). The median duration of response was 25.4 months (95\u200a%CI 8.7\u200a\u2013\u200a42.0) in the GES group and was not reached in the G-POEM group. The Kaplan\u200a\u2013\u200aMeier estimate of 24-month clinical response rate was 76.6\u200a% with G-POEM vs. 53.7\u200a% with GES. GES appeared to have little effect on idiopathic gastroparesis (HR for recurrence with G-POEM vs. GES 0.35, 95\u200a%CI 0.13\u200a\u2013\u200a0.95; P\u200a=\u200a0.05). The incidence of adverse events was higher in the GES group (26.1\u200a% vs. 4.3\u200a%; P\u200a=\u200a0.10).<\/jats:p>\n                  <jats:p>Conclusion\u2002Among patients with refractory gastroparesis, clinical response was better and lasted longer with G-POEM than with GES.\u200aThe positive outcomes with G-POEM are likely to derive from the superior clinical response in patients with idiopathic gastroparesis. Further studies are needed to confirm these findings.<\/jats:p>","DOI":"10.1055\/a-1111-8566","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T19:01:29Z","timestamp":1582311689000},"page":"349-358","source":"Crossref","is-referenced-by-count":55,"title":["Gastric peroral endoscopic pyloromyotomy versus gastric electrical stimulation in the treatment of refractory gastroparesis: a propensity score-matched analysis of long term outcomes"],"prefix":"10.1055","volume":"52","author":[{"given":"Shanshan","family":"Shen","sequence":"first","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"Department of Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Luo","sequence":"first","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi\u2019an, Shaanxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cicily","family":"Vachaparambil","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parit","family":"Mekaroonkamol","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"Division of Gastroenterology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed M.","family":"Abdelfatah","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guifang","family":"Xu","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"Department of Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Xia","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Shi","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"},{"name":"Department of Gastrointestinal Endoscopy, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou, Fujian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Keilin","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Field","family":"Willingham","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Christie","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Cai","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,2,21]]},"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1111-8566.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T18:58:21Z","timestamp":1590087501000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1111-8566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,21]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2020,4,22]]},"published-print":{"date-parts":[[2020,5]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1111-8566","relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,21]]}}}