{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T14:25:56Z","timestamp":1682864756985},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Einleitung Dysgerminome sind seltene maligne Keimzelltumoren des Ovars und in der Schwangerschaft eine Rarit\u00e4t. Neben ovariellen sind au\u00dferhalb der Schwangerschaft auch prim\u00e4r extraovarielle Dysgerminome des Mediastinums und Retroperitoneums beschrieben. Nach ad\u00e4quater chirurgischer und systemischer Therapie besteht eine gute Prognose.<\/jats:p><jats:p>Methodik Bericht eines prim\u00e4r extraovariell-intraabdominalen Dysgerminoms in der Schwangerschaft, systematische Literaturrecherche.<\/jats:p><jats:p>Fallbericht Bei einer 35-j\u00e4hrigen II Gravida wird in der 20. Schwangerschaftswoche ein suspekter intraabdominaler Tumor festgestellt. Bei der folgenden Explorativlaparotomie wird bei unauff\u00e4lligen Ovarien ein Tumorkonglomerat mit Darminfiltration reseziert und ein Dysgerminom diagnostiziert. In der 34. SSW wird eine prim\u00e4re Sectio Caesarea durchgef\u00fchrt, erneuter Tumorbefall komplett reseziert und folgend systemisch Bleomycin, Etoposid und Cisplatin appliziert. Nach 12 Monaten erfolgt bei zystischen Adnexen eine erneute Exploration mit Hysterektomie und Adnexektomie beidseits ohne Nachweis von Malignit\u00e4t. Nach nun 16 Monaten besteht weiter eine Komplettremission.<\/jats:p><jats:p>Zusammenfassung Pr\u00e4sentiert wird die Erstbeschreibung eines prim\u00e4r extraovariell-intraabdominalen Dysgerminoms in der Schwangerschaft. Durch die Entscheidung, die zytoreduktive Operation w\u00e4hrend und die Systemtherapie erst nach Prolongation der Schwangerschaft durchzuf\u00fchren, konnte gr\u00f6\u00dftm\u00f6glicher Benefit f\u00fcr das Kind mit der g\u00fcnstigen Prognose der Mutter vereint werden. Angesichts limitierter Datenlage m\u00fcssen bei Dysgerminomen in der Schwangerschaft individuelle, interdisziplin\u00e4re Konzepte erstellt werden.<\/jats:p>","DOI":"10.1055\/a-1112-0506","type":"journal-article","created":{"date-parts":[[2020,4,3]],"date-time":"2020-04-03T00:26:01Z","timestamp":1585873561000},"page":"306-314","source":"Crossref","is-referenced-by-count":1,"title":["Management Unterbauchraumforderungen in der Schwangerschaft \u2013 Fallbeschreibung eines extraovariell-intraabdominalen Dysgerminoms mit \u00dcberblick \u00fcber die Literatur"],"prefix":"10.1055","volume":"224","author":[{"given":"Christian","family":"Litzka","sequence":"additional","affiliation":[{"name":"Schwerpunkt Geburtshilfe, Krankenhaus Barmherzige Br\u00fcder Regensburg, Frauenklinik Sankt Hedwig, Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"Leebmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Allgemein- und Viszeralchirurgie, Krankenhaus Barmherzige Br\u00fcder Regensburg, Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hellmuth","family":"Wiesinger","sequence":"additional","affiliation":[{"name":"Gemeinschaftspraxis f\u00fcr Pathologie, Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Kirchner","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen, M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Seelbach-G\u00f6bel","sequence":"additional","affiliation":[{"name":"Schwerpunkt Geburtshilfe, Krankenhaus Barmherzige Br\u00fcder Regensburg, Frauenklinik Sankt Hedwig, Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian Franz Martin","family":"H\u00e4usler","sequence":"additional","affiliation":[{"name":"Schwerpunkt Geburtshilfe, Krankenhaus Barmherzige Br\u00fcder Regensburg, Frauenklinik 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