{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T12:35:22Z","timestamp":1710938122462},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"08\/09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gesundheitswesen"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\nZiel In drei Untersuchungsgruppen (Krankenhauspatienten, Bewohner in Altenpflegeheimen und Patienten haus\u00e4rztlicher Praxen) sollte die Pr\u00e4valenz von Methicillin-resistentem Staphylococcus aureus (MRSA), multiresistenten gramnegativen st\u00e4bchenf\u00f6rmigen Bakterien (MRGN) sowie Vancomycin-resistenten Enterokokken (VRE) ermittelt werden. Zudem sollten Risikofaktoren f\u00fcr ein Tr\u00e4gertum untersucht werden.<\/jats:p><jats:p>\nMethodik Das Screening auf multiresistente Erreger (MRE) erfolgte als Punktpr\u00e4valenzuntersuchung bei freiwillig teilnehmenden Personen mittels Nasen-, Rachen- und Rektalabstrich bzw. Stuhlprobe in 25 Krankenh\u00e4usern, 14 Altenpflegeheimen sowie 33 Hausarztpraxen in 12 von 13 Landkreisen in Sachsen. Verd\u00e4chtige Isolate wurden ph\u00e4notypisch sowie z.\u2009T. molekularbiologisch weiter untersucht. Die Teilnehmer f\u00fcllten einen Fragebogen zu vermuteten Risikofaktoren f\u00fcr eine MRE-Besiedlung aus, deren Angaben statistisch mittels Korrelationsanalysen ausgewertet wurden.<\/jats:p><jats:p>\nErgebnisse 1\u2009718 Personen, davon 629 aus Krankenh\u00e4usern, 498 aus Altenpflegeheimen und 591 aus Arztpraxen, wurden untersucht. Insgesamt waren 8,4% aller Teilnehmer Tr\u00e4ger eines MRE. 1,3% wurden positiv auf das Vorliegen eines MRSA, 5,2% auf 3MRGN, 0,1% auf 4MRGN und 2,3% auf VRE getestet. Neun Personen waren mit mehr als einem MRE besiedelt. Folgende unabh\u00e4ngige Faktoren konnten signifikant mit dem Nachweis eines MRE in Zusammenhang gebracht werden: Vorhandensein eines Pflegegrads (MRE), m\u00e4nnliches Geschlecht (MRE\/VRE), aktuelle Antibiose (MRE\/VRE), Antibiose innerhalb der letzten 6 Monate (MRE\/MRSA\/3MRGN\/VRE), aktuelle Tumorerkrankung (MRE\/3MRGN), periphere arterielle Verschlusskrankheit (pAVK) (MRSA) sowie eine Harninkontinenz (3MRGN).<\/jats:p><jats:p>\nSchlussfolgerungen Nach unserem Wissensstand stellt diese Studie die erste Untersuchung zur Pr\u00e4valenz unterschiedlicher multiresistenter Erregergruppen in diesen 3 Untersuchungsgruppen und erstmals dabei auch unter ambulanten Patienten in Deutschland dar. Dabei repr\u00e4sentierten 3MRGN die am h\u00e4ufigsten nachgewiesene Erregergruppe und fanden sich auch in j\u00fcngeren Altersgruppen wieder, VRE wurden fast ausschlie\u00dflich kumuliert in einzelnen Kliniken nachgewiesen. Neben aktueller und stattgehabter Antibiose konnten insbesondere das Vorliegen einer pAVK f\u00fcr MRSA-Nachweise, Harninkontinenz f\u00fcr 3MRGN-Nachweise sowie eine aktuelle Tumorerkrankung f\u00fcr MRE- und 3MRGN-Nachweise als unabh\u00e4ngige Risikofaktoren bestimmt werden.<\/jats:p>","DOI":"10.1055\/a-1138-0489","type":"journal-article","created":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T22:38:48Z","timestamp":1588891128000},"page":"624-631","source":"Crossref","is-referenced-by-count":2,"title":["Multiresistente Bakterien bei Patienten in Krankenh\u00e4usern und Arztpraxen sowie bei Bewohnern von Altenpflegeheimen in Sachsen \u2013 Ergebnisse einer Pr\u00e4valenzstudie 2017\/2018"],"prefix":"10.1055","volume":"83","author":[{"given":"Lydia","family":"Sommer","sequence":"additional","affiliation":[{"name":"Abt. 1, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilo","family":"Hackel","sequence":"additional","affiliation":[{"name":"Abt. 1, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Hofmann","sequence":"additional","affiliation":[{"name":"Abt. 1, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Abt. 1, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekkehard","family":"Hennebach","sequence":"additional","affiliation":[{"name":"SG IT, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate","family":"K\u00f6pke","sequence":"additional","affiliation":[{"name":"Abt. 1, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wiebke","family":"Sydow","sequence":"additional","affiliation":[{"name":"Ref. 23, S\u00e4chsisches Staatsministerium f\u00fcr Soziales und Gesellschaftlichen Zusammenhalt, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Ehrhard","sequence":"additional","affiliation":[{"name":"Abt. 1, Landesuntersuchungsanstalt f\u00fcr das Gesundheits- und Veterin\u00e4rwesen Sachsen, Dresden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris F.","family":"Chaberny","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Hygiene, Krankenhaushygiene und Umweltmedizin, Universitatsklinikum Leipzig, Leipzig"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,5,7]]},"reference":[{"key":"ref1","first-page":"696","article-title":"Kommission f\u00fcr Krankenhaushygiene und Infektionspr\u00e4vention. 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