{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:37:54Z","timestamp":1790689074152,"version":"4.1.0"},"reference-count":170,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die vorliegende Fassung der deutschsprachigen AWMF-Leitlinie soll unter Ber\u00fccksichtigung der vorliegenden Evidenz die medizinische Versorgung von Kindern und Jugendlichen mit ambulant erworbener Pneumonie (pediatric community acquired pneumonia, pCAP) verbessern. In Mitteleuropa steht einer Pr\u00e4valenz von ca. 300 F\u00e4llen pro 100\u200a000 Kinder\/Jahr eine sehr geringe Mortalit\u00e4t gegen\u00fcber, die Pr\u00e4vention umfasst Hygiene-Ma\u00dfnahmen und Impfung z.\u200aB. gegen Pneumokokken, H\u00e4mophilus, Masern und Influenza. Hauptsymptome der pCAP sind Fieber und Tachypnoe, die Diagnosestellung erfolgt prim\u00e4r klinisch durch Anamnese, k\u00f6rperliche Untersuchung und Pulsoxymetrie. Das zus\u00e4tzliche Vorliegen von Warnsymptomen wie stark reduzierter Allgemeinzustand, Nahrungsverweigerung, Dehydratation, Bewusstseinsst\u00f6rung oder Krampfanf\u00e4lle definiert die schwere pCAP in Abgrenzung zur nicht-schweren pCAP. Das Erregerspektrum ist altersabh\u00e4ngig, zur Differenzierung zwischen viraler, bakterieller oder gemischt viral-bakterieller Infektion stehen jedoch keine zuverl\u00e4ssigen Biomarker zur Verf\u00fcgung. Die meisten Kinder und Jugendlichen mit nicht-schwerer pCAP und O2-S\u00e4ttigung &gt;\u200a92\u200a% k\u00f6nnen ohne weitere R\u00f6ntgen-, Labor- und Erreger-Diagnostik ambulant betreut werden. Der Einsatz von Antiinfektiva ist nicht grunds\u00e4tzlich indiziert, vor allem bei jungen Kindern, bronchialer Obstruktion und anderen Hinweisen auf virale Genese kann darauf i.\u200ad.\u200aR. verzichtet werden. Zur kalkulierten Antibiotika-Therapie sind Aminopenicilline Mittel der Wahl, bei gew\u00e4hrleisteter Einnahme und Resorption sind die orale (Amoxicillin) und intraven\u00f6se Verabreichung (Ampicillin) von vergleichbarer Wirksamkeit. Nach 48\u200a\u2013\u200a72 Stunden ist eine Verlaufsbeurteilung notwendig, um den Behandlungserfolg und m\u00f6gliche Komplikationen wie z.\u200aB. parapneumonische Erg\u00fcsse oder Pleuraempyeme, die eine Erweiterung bzw. \u00c4nderung der Therapie erforderlich machen, rechtzeitig zu erfassen.\n<\/jats:p>","DOI":"10.1055\/a-1139-5132","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T22:54:15Z","timestamp":1598050455000},"page":"515-544","source":"Crossref","is-referenced-by-count":14,"title":["S2k-Leitlinie Management der ambulant erworbenen Pneumonie bei Kindern und Jugendlichen (p\u00e4diatrische ambulant erworbene Pneumonie, pCAP)"],"prefix":"10.1055","volume":"74","author":[{"given":"M. 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