{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T11:27:47Z","timestamp":1648898867549},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Einleitung\u2002Das Pylorusdr\u00fcsenadenom (PGA) ist eine unterdiagnostizierte, seltene Entit\u00e4t, die meist im Magen zu finden ist. \u00c4hnlich wie kolorektale Adenome haben PGAs ein hohes Risiko f\u00fcr eine maligne Entartung zum Adenokarzinom von bis zu 12\u201347\u200a%. Endoskopische Resektionen im Duodenum bergen ein erhebliches Risiko f\u00fcr Komplikationen. Die endoskopische Mukosaresektion (EMR) ist die derzeitige Standardtechnik zur Behandlung von duodenalen nichtampull\u00e4ren Adenomen. Die vollst\u00e4ndigen Resektionsraten sind mit etwa 90\u200a% betr\u00e4chtlich hoch. Komplikationen wie Blutungen wurden bis zu 25\u200a% verzeichnet. Die endoskopische Submukosadissektion (ESD) wird f\u00fcr die Resektion von Duodenall\u00e4sionen nicht empfohlen, da die Perforationsrate bis zu 35\u200a% betragen kann. Die Anwendung der endoskopischen Vollwandresektion (EFTR) im Duodenum ist auf eine Fallstudie mit 20 Patienten beschr\u00e4nkt.<\/jats:p><jats:p>\n          Fall\u2002Ein 67-j\u00e4hriger Patient mit attenuierter Polyposis coli (FAP) wurde zum Screening vorgestellt. Die Gastroskopie zeigte eine 20\u200amm gro\u00dfe, nichtampull\u00e4re L\u00e4sion im proximalen Duodenum (Pars I). Die R\u00e4nder der Duodenall\u00e4sionen wurden mit einer Hochfrequenzsonde (HF) markiert. Eine integrierte Ballondilatation (20\u200amm) des oberen \u00d6sophagussphinkters und des Pylorus erleichterte das Vorschieben des Device (FTRD\u00ae, Fa. Ovesco Endoscopy AG, T\u00fcbingen). Nachdem die L\u00e4sion mit einem Greifer in die Kappe gezogen worden war, erfolgte die Applikation der B\u00e4renklaue, und die L\u00e4sion wurde anschlie\u00dfend mit der integrierten Schlinge reseziert. Eine einmalige Antibiotikaprophylaxe mit 2\u200ag Ceftriaxon i.\u200av. wurde w\u00e4hrend der Intervention verabreicht. Die Second-Look-Endoskopie erfolgte 24 Stunden nach der Resektion. Das Resektat zeigte eine PGA von 18\u200amm Gr\u00f6\u00dfe im proximalen Duodenum (immunhistochemisch positiv f\u00fcr Mucin-1, Mucin-5, Mib 1).<\/jats:p><jats:p>\n          Zusammenfassung\u2002Hier pr\u00e4sentieren wir den ersten Fall einer duodenalen EFTR bei einem Patienten mit attenuierter FAP mit Erstbeschreibung eines Pylorusdr\u00fcsenadenoms. Derzeit gibt es keine spezifischen Richtlinien f\u00fcr die Entfernung und \u00dcberwachung. Die ASGE empfiehlt bei Pylorusdr\u00fcsenadenomen eine Resektions- und \u00dcberwachungsendoskopie im Abstand von 3\u20135 Jahren.<\/jats:p>","DOI":"10.1055\/a-1143-6640","type":"journal-article","created":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T22:36:38Z","timestamp":1588890998000},"page":"767-772","source":"Crossref","is-referenced-by-count":0,"title":["Vollwandresektion eines Pylorusdr\u00fcsenadenoms im proximalen Duodenum bei einem 67-j\u00e4hrigen Patienten mit attenuierter Polyposis coli"],"prefix":"10.1055","volume":"58","author":[{"given":"Oliver","family":"Anliker","sequence":"additional","affiliation":[{"name":"Abteilung Gastroenterologie\/Hepatologie der Medizinischen Klinik, Stadtspital Waid, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram","family":"Sieweke","sequence":"additional","affiliation":[{"name":"Abteilung Gastroenterologie\/Hepatologie der Medizinischen Klinik, Stadtspital Waid, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"T\u00f6pfer","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie und Molekularpathologie, Universit\u00e4tsspital Z\u00fcrich, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ines","family":"W\u00fclker","sequence":"additional","affiliation":[{"name":"Ovesco Endoscopy AG, T\u00fcbingen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Breidert","sequence":"additional","affiliation":[{"name":"Abteilung Gastroenterologie\/Hepatologie der Medizinischen Klinik, Stadtspital Waid, Z\u00fcrich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,5,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00428-002-0750-6","article-title":"Pyloric gland adenoma: A clinic pathological analysis of 90 cases","volume":"442","author":"M Vieth","year":"2003","journal-title":"Virchows Arch"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00292-017-0270-4","article-title":"Vorstufen des Magenkarzinoms \u2013 Dysplasie und Adenom","volume":"38","author":"C Langner","year":"2017","journal-title":"Pathologie"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1136\/jclinpath-2014-202553","article-title":"Some observations on pyloric gland adenoma: an uncommon and long ignored entity","volume":"67","author":"M Vieth","year":"2014","journal-title":"J Clin Pathol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00428-018-2400-7","article-title":"Primary small bowel adenomas and adenocarcinomas-recent advances","volume":"473","author":"A Maguire","year":"2018","journal-title":"Virchows Arch"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/PAS.0b013e31817d7ff4","article-title":"Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma","volume":"33","author":"Z M Chen","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"ref6","first-page":"78","volume-title":"Histologic classification of gastric polyps","author":"K Elster","year":"1976"},{"key":"ref7","first-page":"528","article-title":"Gastrale Differenzierung in Adenomen der Magenschleimhaut. 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