{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:23:23Z","timestamp":1788211403654,"version":"build-2803163510"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"10","funder":[{"DOI":"10.13039\/100014103","name":"Key Research and Development Plan of Shandong\nProvince","doi-asserted-by":"crossref","award":["2017G006006"],"award-info":[{"award-number":["2017G006006"]}],"id":[{"id":"10.13039\/100014103","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Metab Res"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although subacute thyroiditis (SAT) is thought to be a self-limited inflammatory\nthyroid disease, the recurrence rate of SAT is approximately\n10\u201320%. It is difficult for these patients to stop\nglucocorticoid treatment, and they are usually bothered with recurrent pain and\nthe side effects of glucocorticoids for more than several months. We describe\nthree cases who were diagnosed with recurrent subacute thyroiditis after a\nreduction in prednisolone (PSL) dose, either immediately upon the cessation of\nPSL or shortly thereafter. Their symptoms, including the adverse effects of PSL,\nseverely impacted their quality of life. After a complete assessment, we\nadministered colchicine at 1 mg per day for 1\u20132 months to control the\nrecurrence of SAT and monitored their routine blood parameters every two weeks.\nAll 3 patients were successfully tapered off of PSL treatment and were free of\nfrequently recurrent SAT. Colchicine may be therapeutic in patients with\nprednisolone-refractory, recurrent SAT. However, a large-scale, double-blind,\ncontrolled, prospective multicenter study is required to provide a solid body of\nevidence.<\/jats:p>","DOI":"10.1055\/a-1148-2260","type":"journal-article","created":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T23:02:59Z","timestamp":1588633379000},"page":"712-717","source":"Crossref","is-referenced-by-count":14,"title":["Successful Management of Recurrent Subacute Thyroiditis by Adding Colchicine to Glucocorticoid Treatment: A Case Series Study"],"prefix":"10.1055","volume":"52","author":[{"given":"Zhenhua","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shandong Provincial\nHospital, Cheeloo College of Medicine, Shandong University,\nJinan, Shandong, China;"},{"name":"Department of Endocrinology, Shandong Provincial\nHospital Affiliated to Shandong First Medical University,\nJinan, Shandong, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shandong Provincial\nHospital, Cheeloo College of Medicine, Shandong University,\nJinan, Shandong, China;"},{"name":"Shandong Provincial Key Laboratory of Endocrinology\nand Lipid Metabolism, Jinan, Shandong, China;"},{"name":"Institute of Endocrinology and Metabolism, Shandong\nAcademy of Clinical Medicine, Jinan, Shandong, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shandong Provincial\nHospital, Cheeloo College of Medicine, Shandong University,\nJinan, Shandong, China;"},{"name":"Shandong Provincial Key Laboratory of Endocrinology\nand Lipid Metabolism, Jinan, Shandong, China;"},{"name":"Institute of Endocrinology and Metabolism, Shandong\nAcademy of Clinical Medicine, Jinan, Shandong, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiujuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shandong Provincial\nHospital, Cheeloo College of Medicine, Shandong University,\nJinan, Shandong, China;"},{"name":"Department of Endocrinology, Shandong Provincial\nHospital Affiliated to Shandong First Medical University,\nJinan, Shandong, China;"},{"name":"Shandong Provincial Key Laboratory of Endocrinology\nand Lipid Metabolism, Jinan, Shandong, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingbo","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shandong Provincial\nHospital, Cheeloo College of Medicine, Shandong University,\nJinan, Shandong, China;"},{"name":"Department of Endocrinology, Shandong Provincial\nHospital Affiliated to Shandong First Medical University,\nJinan, Shandong, China;"},{"name":"Shandong Provincial Key Laboratory of Endocrinology\nand Lipid Metabolism, Jinan, Shandong, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,5,4]]},"reference":[{"key":"ref1","first-page":"536","volume-title":"Subacute thyroiditis and acute infectious thyroiditis","author":"A P Farwell","year":"2005"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1089\/thy.1993.3.253","article-title":"The management of subacute (DeQuervain's) thyroiditis","volume":"3","author":"R Volpe","year":"1993","journal-title":"Thyroid"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"725","DOI":"10.2169\/internalmedicine.47.0740","article-title":"Clinical characteristics of 852 patients with subacute thyroiditis before\ntreatment","volume":"47","author":"E Nishihara","year":"2008","journal-title":"Inter Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/BF03347442","article-title":"Subacute thyroiditis: clinical 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