{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T15:12:01Z","timestamp":1648912321186},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Im aufmerksamen Wachzustand verl\u00e4ngern angenehme Ger\u00fcche h\u00e4ufig die Einatmung, w\u00e4hrend unangenehme Ger\u00fcche h\u00e4ufig die Ausatmung verk\u00fcrzen. Es soll \u00fcberpr\u00fcft werden, ob dieses induzierte Atemmuster auch im Schlaf erhalten bleibt.<\/jats:p><jats:p>\n          Methodik\u200223 gesunde normosmische Erwachsene wurden f\u00fcr 1 Nacht polysomnografisch untersucht und dabei entweder mit H2S, Phenylethylalkohol (PEA) oder CO2 \u00fcber ein Fluss-Olfaktometer randomisiert impulsartig gereizt. Anhand der standardm\u00e4\u00dfig erfassten Polysomnografie-Kurven erfolgte die Bestimmung der Schlafstadien (REM, NREM, pWach), der Dauer der Inspiration (DIN) und der Dauer der Exspiration (DEX). DIN\u200aund DEX wurden von 6 pr\u00e4stimulatorischen Atemz\u00fcgen und vom Reizatemzug (RAZ) bestimmt. Daraus wurde der Reaktionsindex (RI) berechnet, der angibt, ob eine bedeutsame \u00c4nderung von DIN\u200aund\/oder DEX vorliegt. Die verschiedenen RI wurden um die spontanen RI korrigiert und entsprechend der Reizart und den Schlafstadien analysiert.<\/jats:p><jats:p>\n          Ergebnis\u2002Reaktionsindizes mit Verk\u00fcrzungen von DEX waren bei einer H2S-Reizung gr\u00f6\u00dfer als spontane RI und RI bei einer PEA-Reizung. Bei einer CO2-Reizung waren RI mit Verk\u00fcrzungen von DIN\u200aund DEX gr\u00f6\u00dfer als bei olfaktorischer Reizung. Alle RI waren in ihrer Auspr\u00e4gung zwischen den Schlafstadien gleich. Im REM war der Unterschied der olfaktorischen RI mit verk\u00fcrzten DEX zwischen einer H2S- und PEA-Reizung am gr\u00f6\u00dften.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Bei Reizung mit einem unangenehmen Geruch im Schlaf bleibt das respiratorische Reaktionsmuster aus dem Wachzustand erhalten. RI mit verk\u00fcrzten DEX k\u00f6nnen als unvollkommene Arousals angesehen werden.<\/jats:p>","DOI":"10.1055\/a-1157-9314","type":"journal-article","created":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T23:08:52Z","timestamp":1588201732000},"page":"620-627","source":"Crossref","is-referenced-by-count":1,"title":["Schwefelwasserstoffreize verk\u00fcrzen im Schlaf- wie im Wachzustand die Ausatmung"],"prefix":"10.1055","volume":"99","author":[{"given":"Hilmar","family":"Gudziol","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Jena\u00a0University Hospital, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Quaas","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Jena\u00a0University Hospital, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orlando","family":"Guntinas-Lichius","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Jena\u00a0University Hospital, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Lehnich","sequence":"additional","affiliation":[{"name":"Medizinische Fakult\u00e4t ZMG, Martin-Luther-Universit\u00e4t Halle-Wittenberg, Halle, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Bitter","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Jena\u00a0University Hospital, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,4,29]]},"reference":[{"key":"ref1","first-page":"402","article-title":"Minimal olfactory perception during sleep: why odor alarms will not work for 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