{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T15:05:39Z","timestamp":1791039939600,"version":"4.1.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Einleitung\u2002Zur Wertigkeit einer Wunddrainage bei einer Parotidektomie existieren keine validen klinischen Studien. Das Ziel der aktuellen Studie ist es zu untersuchen, ob durch die Einlage bzw. den Verzicht auf eine geschlossene Wunddrainage (sog. Redon) bei einer lateralen und partiellen Parotidektomie die H\u00e4ufigkeit der postoperativen Komplikationen, wie Nachblutung, Wundheilungsst\u00f6rung und Wundinfektion sowie Speichelzyste und -fistel beeinflusst wird.<\/jats:p><jats:p>Methoden\u2002Es wurde eine europaweite multizentrische, prospektive, randomisierte Studie geplant. Durch das Hauptpr\u00fcfzentrum (HNO-Uniklinik K\u00f6ln), in Kooperation mit den HNO-Universit\u00e4tskliniken Jena und G\u00f6ttingen, wurde das Studienprotokoll erstellt. Die Fallzahlberechnung wurde mit G*Power durchgef\u00fchrt. Die Studie umfasst Probanden mit einer Indikation zu Parotidektomie bei einem gutartigen Tumor ohne bekannte Gerinnungsst\u00f6rung oder weitergef\u00fchrte Antikoagulation. Die pr\u00e4operative Randomisierung und das Data Management erfolgen softwaregest\u00fctzt (REDCap 9.1.24, Vanderbilt University).<\/jats:p><jats:p>Ergebnisse\u2002Die Studie wurde 10\/2019 durch die federf\u00fchrende Ethikkommission zustimmend bewertet und ist seit April 2019 offen. Zum aktuellen Zeitpunkt nehmen 9 HNO-Kliniken, davon 6 in Deutschland und 3 in \u00d6sterreich, an der Studie teil. Hierbei werden in 7 Zentren aktiv Probanden eingeschlossen. Bei einer kalkulierten Follow-to-treat-Gruppengr\u00f6\u00dfe von 800\u00a0Probanden betr\u00e4gt die geplante Laufzeit der Studie 4 Jahre.<\/jats:p><jats:p>Schlussfolgerungen\u2002Die Redon-Studie ist die weltweit erste prospektive randomisierte Studie, die die Wertigkeit einer Drainageeinlage bei einer Parotidektomie untersucht. Um das Rekrutierungsziel in geplanter Zeit erreichen zu k\u00f6nnen, ist die Teilnahme weiterer spezialisierter Kliniken dringend notwendig. Wir m\u00f6chten zudem alle HNO-\u00c4rzte ermutigen, ihre Patienten auf die Redon-Studie aufmerksam zu machen, sie \u00fcber die M\u00f6glichkeit zur Studienteilnahme aufzukl\u00e4ren und in eine der teilnehmenden Kliniken zu \u00fcberweisen.<\/jats:p>","DOI":"10.1055\/a-1178-0800","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T22:44:45Z","timestamp":1591742685000},"page":"46-53","source":"Crossref","is-referenced-by-count":2,"title":["Vorstellung einer europaweiten prospektiven Studie zur Wertigkeit einer Drainage bei Parotidektomie"],"prefix":"10.1055","volume":"100","author":[{"given":"Maria","family":"Grosheva","sequence":"additional","affiliation":[{"name":"HNO Uniklinik K\u00f6ln, Medizinische Fakult\u00e4t, University of Cologne, K\u00f6ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Peter","family":"Klu\u00dfmann","sequence":"additional","affiliation":[{"name":"HNO Uniklinik K\u00f6ln, Medizinische Fakult\u00e4t, University of Cologne, K\u00f6ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Beutner","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Georg-August-Universit\u00e4t G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Formanek","sequence":"additional","affiliation":[{"name":"HNO und Phoniatrie, Krankenhaus der Barmherzigen Br\u00fcder, Wien, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Lill","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Kopf- und Halserkrankungen, Evangelisches Krankenhaus Wien, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Laskawi","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Georg-August-Universit\u00e4t G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Zenk","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universit\u00e4tsklinikum Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Pick","sequence":"additional","affiliation":[{"name":"HNO Uniklinik K\u00f6ln, Medizinische Fakult\u00e4t, University of Cologne, K\u00f6ln, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Erlacher","sequence":"additional","affiliation":[{"name":"HNO und Phoniatrie, Krankenhaus der Barmherzigen Br\u00fcder, Wien, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Bemmer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Georg-August-Universit\u00e4t G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovanna","family":"Thielker","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Universit\u00e4tsklinikum Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Jering","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universit\u00e4tsklinikum Augsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Tostmann","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Hals-Nasen-Ohrenheilkunde, Georg-August-Universit\u00e4t G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orlando","family":"Guntinas-Lichius","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universit\u00e4tsklinikum Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,6,9]]},"reference":[{"key":"ref1","first-page":"620","article-title":"Station\u00e4re Speicheldr\u00fcsenoperationen in Deutschland. 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