{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T21:19:18Z","timestamp":1688159958908},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Klin Monbl Augenheilkd"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background In earlier studies, an irregular tear film could be responsible for artifacts in imaging procedures in ophthalmology. As a result, this study will investigate the influence of hyaluronic acid-containing tear substitutes of different viscosities on the measurement results of optical coherence tomography and on the non-invasive tear film break-up time.<\/jats:p><jats:p>\n          Methods The study included three sessions in which three hyaluronic acid tear substitutes of different viscosities (Hylo-Vision 0.1%, 0.2%, 0.3%, OmniVision GmbH, Puchheim, Germany) were applied to each subject. In 20 healthy volunteers, the non-invasive tear film break-up time was measured before and after the application of the tear substitutes using Keratograph 5M (Oculus GmbH, Wetzlar, Germany) and optical coherence tomography using 3D OCT-2000 (Topcon, Hamburg, Germany).<\/jats:p><jats:p>\n          Results The median age of the volunteers was 28.5 years. 11\u00a0women (55%) and 9 men (45%) were examined. The non-invasive tear film break-up time improved significantly (p\u2009=\u20090.027) after the application of 0.3% hyaluronic acid. In the study, no significant difference was found in all OCT parameters used before and after application of the different viscous hyaluronic acid-containing tear substitutes.<\/jats:p><jats:p>\n          Conclusion In this study, no influence of tear substitutes containing different viscosities of hyaluronic acid on the measurement results of optical coherence tomography could be determined. Therefore, 0.1%, 0.2% and 0.3% hyaluronic acid can be applied to the patient to improve the corneal surface before the examination with optical coherence tomography, without influencing the measurement results of optical coherence tomography.<\/jats:p>","DOI":"10.1055\/a-1179-0131","type":"journal-article","created":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T22:46:00Z","timestamp":1602283560000},"page":"1004-1009","source":"Crossref","is-referenced-by-count":1,"title":["The Impact of Artificial Tear Viscosity on the Results of Optical Coherence Tomography"],"prefix":"10.1055","volume":"238","author":[{"given":"Elisa","family":"Hannemann","sequence":"additional","affiliation":[{"name":"Optometrie, Fachbereich VII, Beuth Hochschule f\u00fcr Technik, Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Erb","sequence":"additional","affiliation":[{"name":"Augenklinik am Wittenbergplatz, Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,10,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1007\/s00417-008-0881-9","article-title":"German register for glaucoma patients with dry eye. 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