{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T05:24:49Z","timestamp":1669008289956},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Einleitung\u2002Das Tako-Tsubo-Syndrom (TTS) beschreibt eine transiente ventrikul\u00e4re Dysfunktion. Symptome und Komplikationsrate \u00e4hneln denen eines Myokardinfarkts.<\/jats:p><jats:p>Anamnese\u2002Eine 81-j\u00e4hrige Patientin wurde zur Thrombendarteriektomie der linken Femoralarterie aufgenommen. Kurz zuvor war ein biologischer Aortenklappenersatz durchgef\u00fchrt und eine koronare Herzkrankheit ausgeschlossen worden.<\/jats:p><jats:p>Narkoseeinleitung und klinischer Befund\u2002Nach Narkoseeinleitung kam es zu einer relevanten arteriellen Hypotonie und Sinusbradykardie. Nach Katecholamin-Gabe zeigten sich transient angehobene ST-Strecken, welche postoperativ eine Myokardinfarkt-\u00e4hnliche Dynamik entwickelten. Echokardiografisch und in den kardialen Enzymen waren initial keine Au\ufb00\u00e4lligkeiten zu beobachten.<\/jats:p><jats:p>Therapie, Verlauf und Diagnose\u2002Nach einem symptomfreien Intervall entwickelte die Patienten am dritten postoperativen Tag unvermittelt eine schwere kardiale Dekompensation. Nun war das Vollbild eines TTS zu erkennen. Unter Therapie mit Levosimendan gelang eine Stabilisierung des klinischen Zustands.<\/jats:p><jats:p>Folgerung\u2002Dynamische EKG-Ver\u00e4nderungen in der perioperativen Situation erfordern stets eine di\ufb00erenzierte Diagnostik und ggf. eine l\u00e4ngere \u00dcberwachung. Das TTS ist hierbei eine relevante und komplikationsbehaftete Di\ufb00erenzialdiagnose.<\/jats:p>","DOI":"10.1055\/a-1185-7007","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T22:35:31Z","timestamp":1600986931000},"page":"1400-1404","source":"Crossref","is-referenced-by-count":0,"title":["Das versp\u00e4tete Tako-Tsubo-Syndrom \u2013 Ein kritischer perioperativer Zwischenfall"],"prefix":"10.1055","volume":"145","author":[{"given":"Tillmann","family":"Speer","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr An\u00e4sthesiologie, Klinikum Itzehoe, Itzehoe, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko","family":"Fiege","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr An\u00e4sthesiologie, Klinikum Itzehoe, Itzehoe, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Fastner","sequence":"additional","affiliation":[{"name":"I. Medizinische Klinik \u2013 Kardiologie, Angiologie, Pneumologie, Internistische Intensivmedizin und H\u00e4mostaseologie, Universit\u00e4tsmedizin Mannheim (UMM), Medizinische Fakult\u00e4t Mannheim der Universit\u00e4t Heidelberg und Deutsches Zentrum f\u00fcr Herz-Kreislauf-Forschung (DZHK), Standort Heidelberg\/Mannheim, Mannheim, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,9,24]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1093\/eurheartj\/ehy076","article-title":"International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology","volume":"39","author":"J R Ghadri","year":"2018","journal-title":"Eur Heart J"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1093\/eurheartj\/ehy077","article-title":"International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management","volume":"39","author":"J R Ghadri","year":"2018","journal-title":"Eur Heart J"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.carrev.2018.11.016","article-title":"Takotsubo syndrome: State-of-the-art review by an expert panel \u2013 Part 2","volume":"20","author":"A Dias","year":"2019","journal-title":"Cardiovasc Revasc Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1056\/NEJMoa1406761","article-title":"Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy","volume":"373","author":"C Templin","year":"2015","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1177\/1089253217700511","article-title":"Perioperative Takotsubo Cardiomyopathy: A Systematic Review of Published Cases","volume":"21","author":"S Agarwal","year":"2017","journal-title":"Semin Cardiothorac Vasc Anesth"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.carrev.2018.11.015","article-title":"Takotsubo syndrome: State-of-the-art review by an expert panel \u2013 Part 1","volume":"20","author":"A Dias","year":"2019","journal-title":"Cardiovasc Revasc Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jacc.2009.08.057","article-title":"Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy","volume":"55","author":"S W Sharkey","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1161\/01.RES.52.1.16","article-title":"Prejunctional and postjunctional actions of endogenous norepinephrine at the sympathetic neuroe\ufb00ector junction in canine coronary arteries","volume":"52","author":"R A Cohen","year":"1983","journal-title":"Circ Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1080\/08998280.2016.11929402","article-title":"Takotsubo cardiomyopathy after administration of norepinephrine","volume":"29","author":"K Sherif","year":"2016","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.ijcard.2013.08.126","article-title":"Time course of electrocardiographic changes in transient left ventricular ballooning syndrome","volume":"169","author":"J Bennett","year":"2013","journal-title":"Int J Cardiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s12181-012-0417-8","article-title":"Konsensusempfehlungen der DRG\/DGK\/DGPK zum Einsatz der Herzbildgebung mit Computertomografie und Magnetresonanztomografie","volume":"6","author":"S Achenbach","year":"2012","journal-title":"Kardiologe"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/europace\/eux073","article-title":"Prevalence of malignant arrhythmia and sudden cardiac death in takotsubo syndrome and its management","volume":"20","author":"I El-Battrawy","year":"2018","journal-title":"Europace"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1093\/qjmed\/hcw092","article-title":"Comparison and outcome analysis of patients with apical and non-apical takotsubo cardiomyopathy","volume":"109","author":"I El-Battrawy","year":"2016","journal-title":"QJM"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3389\/fpsyg.2017.00527","article-title":"Comparison and Outcome Analysis of Patients with Takotsubo Cardiomyopathy Triggered by Emotional Stress or Physical Stress","volume":"8","author":"G Konstantinos","year":"2017","journal-title":"Front Psychol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e010753","DOI":"10.1161\/JAHA.118.010753","article-title":"Incidence and Clinical Impact of Recurrent Takotsubo Syndrome: Results From the GEIST Registry","volume":"8","author":"I El-Battrawy","year":"2019","journal-title":"J\u00a0Am Heart Assoc"}],"container-title":["DMW - 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