{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T11:54:17Z","timestamp":1687607657387},"reference-count":39,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Gegenstand und Ziel Die Pr\u00e4valenz von antibiotikaresistenten Bakterien bei Zier-, Zoo- und falknerisch gehaltenen Greifv\u00f6geln ist noch weitgehend unbekannt. Daher sollten retrospektiv Antibiogramme schnellwachsender aerober Bakterienarten ausgewertet werden.<\/jats:p><jats:p>\n          Material und Methoden Im Auswertungszeitraum von 2007 bis 2016 standen 1036 Antibiogramme zur Verf\u00fcgung. Die Bakterienisolate stammten vorzugsweise aus S\u00fcddeutschland und von 811 V\u00f6geln aus 20 zoologischen Ordnungen (am h\u00e4ufigsten Papageienv\u00f6gel [61,8 %] und Sperlingsv\u00f6gel [14,5 %]) sowie aus Proben von klinischen Patienten und Sektionsmaterial. Die ph\u00e4notypische In-vitro-Empfindlichkeit wurde mittels Plattendiffusionstest ermittelt.<\/jats:p><jats:p>\n          Ergebnisse Die meisten Antibiogramme lagen f\u00fcr E. coli (n = 386 Isolate) vor, gefolgt von Staphylococcus (S.). aureus (n = 150), Enterobacter cloacae (n = 122), Klebsiella pneumoniae (n = 86) und Pseudomonas aeruginosa (n = 64). Resistenzen gegen mindestens einen antibiotischen Wirkstoff zeigten 53,1 % der E. coli-Isolate, dabei am h\u00e4ufigsten gegen Doxycyclin (50,3 %) und Ampicillin (46,1 %). Bei 78,0 % der S. aureus-Isolate und bei 95,9 % der Enterococcus faecalis-Isolate wurden Resistenzen gegen\u00fcber mindestens einem Wirkstoff nachgewiesen. Multiresistenzen (Resistenz gegen\u00fcber \u2265 3 Antibiotikagruppen) traten bei 37,3 % der Isolate von S. aureus auf. Bei Isolaten von Zier- und Greifv\u00f6geln wurden h\u00f6here Resistenzraten festgestellt als bei Isolaten von Zoov\u00f6geln und bei Papageienv\u00f6geln h\u00f6here Resistenzraten als bei Sperlingsv\u00f6geln. Im Untersuchungszeitraum zeigte sich bei E. coli ein tendenzieller Anstieg der Resistenzrate f\u00fcr Fluorchinolone (Minimum von 0 % im Jahr 2013 und Maximum von 27,3 % im Jahr 2015) und bei S. aureus eine tendenzielle Abnahme der Resistenzraten f\u00fcr Tetrazykline (Maximum von 39,4 % im Jahr 2007 und Minimum von 0 % in den Jahren 2014 und 2015).<\/jats:p><jats:p>\n          Schlussfolgerung und klinische Relevanz Die Resistenzsituation von Bakterien aus Zier-, Zoo- und falknerisch gehaltenen Greifv\u00f6geln ist als problematisch zu bewerten und verdeutlicht die Wichtigkeit der Empfindlichkeitspr\u00fcfung f\u00fcr eine gewissenhafte Therapie. Im Fall einer Infektion mit S. aureus bei Zier-, Zoo- oder falknerisch gehaltenen Greifv\u00f6geln kann es zu einem Therapienotstand kommen.<\/jats:p>","DOI":"10.1055\/a-1199-6223","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T22:51:56Z","timestamp":1598050316000},"page":"260-269","source":"Crossref","is-referenced-by-count":1,"title":["Ph\u00e4notypische Antibiotikaresistenzen von Bakterienisolaten aus Zier-, Zoo- und falknerisch gehaltenen Greifv\u00f6geln"],"prefix":"10.1055","volume":"48","author":[{"given":"Leonie","family":"Steger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr V\u00f6gel, Kleins\u00e4uger, Reptilien und Zierfische, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Rinder","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr V\u00f6gel, Kleins\u00e4uger, Reptilien und Zierfische, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcdiger","family":"Korbel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr V\u00f6gel, Kleins\u00e4uger, Reptilien und Zierfische, Zentrum f\u00fcr Klinische Tiermedizin, Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,8,21]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1258\/jrsm.2009.09k036","article-title":"The introduction of \u2018chemotherapy\u2019 using arsphenamine \u2013 the first magic bullet","volume":"102","author":"K J Williams","year":"2009","journal-title":"J R Soc Med"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"426","DOI":"10.2105\/AJPH.2012.300693","article-title":"Rethinking antibiotic research and development: World War II and the penicillin collaborative","volume":"103","author":"R Quinn","year":"2013","journal-title":"Am J Public Health"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"e34953","DOI":"10.1371\/journal.pone.0034953","article-title":"Antibiotic resistance is prevalent in an isolated cave microbiome","volume":"7","author":"K Bhullar","year":"2012","journal-title":"PLoS One"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1080\/10410236.2014.943634","article-title":"Antibiotic resistance: a primer and call to action","volume":"30","author":"R A Smith","year":"2015","journal-title":"Health Commun"},{"key":"ref5","first-page":"417","volume-title":"Chemotherapie bakterieller Infektionen","author":"R Kroker","year":"2009","edition":"3. Aufl."},{"issue":"05","key":"ref7","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s00103-018-2729-8","article-title":"Die Umwelt als Reservoir f\u00fcr Antibiotikaresistenzen. Ein wachsendes Problem f\u00fcr die \u00f6ffentliche Gesundheit?","volume":"61","author":"K Westphal-Settele","year":"2018","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1128\/CMR.00030-10","article-title":"Challenges of antibacterial discovery","volume":"24","author":"L L Silver","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"ref12","first-page":"368","article-title":"Anstrengungen der Tiermedizin zur Reduktion von Antibiotikaresistenzen","volume":"74","author":"M Muehlhaupt","year":"2019","journal-title":"Bayerisches \u00c4rzteblatt"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.ijmm.2011.09.009","article-title":"Methicillin-resistant staphylococci (MRS) and extended-spectrum beta-lactamases (ESBL)-producing Enterobacteriaceae in companion animals: nosocomial infections as one reason for the rising prevalence of these potential zoonotic pathogens in clinical samples","volume":"301","author":"L H Wieler","year":"2011","journal-title":"Int J Med Microbiol"},{"issue":"S 01","key":"ref15","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/j.jcpa.2015.03.004","article-title":"Bacterial Zoonoses Transmitted by Household Pets: State-of-the-Art and Future Perspectives for Targeted Research and Policy Actions","volume":"155","author":"P Damborg","year":"2016","journal-title":"J Comp Pathol"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00103-015-2261-z","article-title":"Antibiotika-resistente Erreger in Deutschland. Die Rolle von nicht nosokomialen Ansteckungsquellen","volume":"59","author":"E A Idelevich","year":"2016","journal-title":"Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz"},{"issue":"09","key":"ref17","doi-asserted-by":"crossref","first-page":"e76150","DOI":"10.1371\/journal.pone.0076150","article-title":"Characterization and comparison of extended-spectrum beta-lactamase (ESBL) resistance genotypes and population structure of Escherichia coli isolated from Franklin\u2019s gulls (Leucophaeus pipixcan) and humans in Chile","volume":"8","author":"J Hernandez","year":"2013","journal-title":"PLoS One"},{"key":"ref18","volume-title":"Vorkommen und Bedeutung von Antibiotikaresistenzen und Extended-Spectrum Beta-Lactamasen (ESBL) bei Escherichia coli aus Wildv\u00f6geln mit Kontakt zu Menschen aus S\u00fcdbayern [Dissertation]","author":"C Gerhofer","year":"2015"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.vetmic.2016.04.008","article-title":"Comparative virulotyping of extended-spectrum cephalosporin-resistant E. coli isolated from broilers, humans on broiler farms and in the general population and UTI patients","volume":"194","author":"A H van Hoek","year":"2016","journal-title":"Vet Microbiol"},{"issue":"05","key":"ref20","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s12275-017-6523-3","article-title":"Wild birds and urban pigeons as reservoirs for diarrheagenic Escherichia coli with zoonotic potential","volume":"55","author":"C A Borges","year":"2017","journal-title":"J Microbiol"},{"key":"ref21","volume-title":"Die Beziehung von Menschen zu ihren V\u00f6geln in der Heimtierhaltung: eine empirisch-tier\u00e4rztliche Studie unter Entwicklung einer psychometrischen Skala der Mensch-Vogel-Beziehung. [Dissertation]","author":"A-K Burmeister","year":"2016"},{"key":"ref22","volume-title":"Ph\u00e4notypische Antibiotikaresistenzen schnellwachsender aerober Bakterien von ZIer-, Zoo- und Beizv\u00f6geln. [Dissertation]","author":"L Steger","year":"2019"},{"issue":"12","key":"ref23","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1111\/j.1348-0421.1980.tb02918.x","article-title":"Drug resistance and R plasmids in Escherichia coli strains isolated from imported pet birds","volume":"24","author":"M Nakamura","year":"1980","journal-title":"Microbiol Immunol"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.apjtm.2016.10.003","article-title":"In vitro biofilm formation in ESBL producing Escherichia coli isolates from cage birds","volume":"9","author":"E S Yilmaz","year":"2016","journal-title":"Asian Pac J Trop Med"},{"issue":"02","key":"ref25","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1080\/03079457.2016.1142066","article-title":"Virulence and antimicrobial resistance of Klebsiella pneumoniae isolated from passerine and psittacine birds","volume":"45","author":"Y M Davies","year":"2016","journal-title":"Avian Pathol"},{"issue":"02","key":"ref26","first-page":"593","article-title":"Report \u2013 Susceptibility of avian pathogenic Escherichia coli from zoo birds in Indonesia to antibiotics and disinfectants","volume":"31","author":"S Umar","year":"2018","journal-title":"Pak J Pharm Sci"},{"issue":"01","key":"ref27","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1053\/j.jepm.2014.12.009","article-title":"Antibiotic-resistance patterns of gram-negative bacterial isolates from breeder canaries (Serinus canaria domestica) with clinical disease","volume":"24","author":"C Giacopello","year":"2015","journal-title":"J Exot Pet Med"},{"issue":"02","key":"ref28","first-page":"73","article-title":"Reproductive disorders in domestic canaries (Serinus canarius domesticus): a retrospective study on bacterial isolates and their antimicrobial resistance in Italy from 2009 to 2012","volume":"54","author":"C E Di Francesco","year":"2018","journal-title":"Vet Ital"},{"issue":"04","key":"ref29","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/vms3.38","article-title":"Antibiotic resistance in conjunctival and enteric bacterial flora in raptors housed in a zoological garden","volume":"2","author":"A Sala","year":"2016","journal-title":"Vet Med Sci"},{"key":"ref30","first-page":"263","article-title":"Zur derzeitigen Resistenzlage von klinisch bedeutsamen Bakterienisolaten aus verschiedenen Vogelspezies","volume":"27","author":"K Ravelhofer-Rotheneder","year":"1999","journal-title":"Tier\u00e4rztl Prax"},{"issue":"03","key":"ref31","first-page":"1","article-title":"Leitlinien f\u00fcr den sorgf\u00e4ltigen Umgang mit antibakteriell wirksamen Tierarzneimitteln \u2013 mit Erl\u00e4uterungen","volume":"63","author":"Anonymous","year":"2015","journal-title":"Dtsch Tier\u00e4rztebl"},{"issue":"05","key":"ref32","first-page":"501","article-title":"Zur Antibiotikaresistenz wichtiger Bakterien aus dem Klinik- und Sektionsmaterial des Instituts f\u00fcr Gefl\u00fcgelkrankheiten","volume":"18","author":"H Gerlach","year":"1990","journal-title":"Tierarztl Prax"},{"key":"ref34","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals","author":"CLSI","year":"2013"},{"key":"ref35","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals","author":"CLSI","year":"2008","edition":"3 rd edition"},{"key":"ref36","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals, 4th edition","author":"CLSI","year":"2018"},{"key":"ref37","volume-title":"Performance standards for antimicrobial susceptibility testing","author":"CLSI","year":"2018","edition":"28th edition"},{"key":"ref38","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals, 5th ed, VET01Ed5E","author":"CLSI","year":"2018"},{"issue":"09\/10","key":"ref39","first-page":"353","article-title":"Empfindlichkeitspr\u00fcfung bakterieller Infektionserreger von Tieren gegen\u00fcber antimikrobiellen Wirkstoffen: Methoden zur in-vitro Empfindlichkeitspr\u00fcfung und deren Eignung in Hinblick auf die Erarbeitung therapeutisch nutzbarer Ergebnisse","volume":"116","author":"S Schwarz","year":"2003","journal-title":"Berl Munch Tierarztl Wochenschr"},{"key":"ref40","volume-title":"Untersuchungen zur in-vitro-Antibiotikaempfindlichkeit aerober Bakterien beim Wirtschaftsgefl\u00fcgel mittels Agardiffusionstest und Bouillon-Mikrodilutionsmethode [Dissertation]","author":"F Kronthaler","year":"2009"},{"key":"ref41","first-page":"949","volume-title":"Bacteria","author":"H Gerlach","year":"1994"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.scitotenv.2017.09.004","article-title":"Distribution of species and antimicrobial resistance among enterococci isolated from the fecal microbiota of captive blue-fronted parrot (Amazona aestiva) in Rio de Janeiro, Brazil","volume":"615","author":"A AR Freitas","year":"2018","journal-title":"Sci Total Environ"},{"issue":"01","key":"ref43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/595011","article-title":"Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America","volume":"48","author":"H W Boucher","year":"2009","journal-title":"Clin Infect Dis"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jgar.2017.10.007","article-title":"Clonal dissemination of OXA-48-producing Enterobacter cloacae isolates from companion animals in Algeria","volume":"12","author":"M Yousfi","year":"2018","journal-title":"J Glob Antimicrob Resist"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"690","DOI":"10.2307\/1592704","article-title":"Antimicrobial resistance and minimum inhibitory concentrations of bacteria isolated from bustards in the United Arab Emirates","volume":"42","author":"T A Bailey","year":"1998","journal-title":"Avian Dis"}],"container-title":["Tier\u00e4rztliche Praxis Ausgabe K: Kleintiere \/ Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1199-6223.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T22:52:57Z","timestamp":1598050377000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1199-6223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":39,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2020,8,21]]},"published-print":{"date-parts":[[2020,8]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1199-6223","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"value":"1434-1239","type":"print"},{"value":"2567-5842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}