{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:04:03Z","timestamp":1787807043812,"version":"build-2784847793"},"reference-count":33,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aktuelle Urol"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Tamsulosin ist eines der am h\u00e4ufigsten verschriebenen alpha-1A-Antagonisten zur Behandlung des benignen Prostatasyndrom (BPS). Bei einer Kataraktoperation entwickeln diese Patienten h\u00e4ufig ein intraoperatives floppy Iris Syndrom (IFIS). Dabei kommt es zu einer zunehmenden Miosis und einer undulierenden Iris, welches das Komplikationsrisiko deutlich erh\u00f6ht und bleibende Sch\u00e4den verursachen kann.<\/jats:p><jats:p>\n          Ziel der Arbeit\u2002Ziel ist es Bewusstsein f\u00fcr die Folgen einer Tamsulosineinnahme bei Kataraktoperationen zu schaffen.<\/jats:p><jats:p>\n          Material und Methoden\u2002Wir f\u00fchrten eine Review der ver\u00f6ffentlichten Publikationen \u00fcber die Assoziation von IFIS bei Kataraktoperation mit Alpharezeptorblockern durch.<\/jats:p><jats:p>\n          Ergebnisse und Diskussion Tamsulosin hat ein bis zu 80\u200a%-iges Risiko f\u00fcr Komplikationen, wohingegen Doxazosin und Alfuzosin lediglich eine Komplikationswahrscheinlichkeit von 15\u201320\u200a% haben. Tamsulosin stellt somit einen erheblichen Risikofaktor f\u00fcr permanente Folgesch\u00e4den nach Kataraktoperation dar. Auch nach Absetzen von Tamsulosin wurden noch nach bis zu 3 Jahren IFIS beobachtet, ein pausieren vor Katarakoperation wird dennoch empfohlen. Ein Alternativpr\u00e4parat sollte somit bei Patienten, die noch keine Kataraktoperation erhalten haben, bevorzugt werden. Sind die Patienten bereits kataraktoperiert, kann Tamsulosin ohne Bedenken gegeben werden.<\/jats:p>","DOI":"10.1055\/a-1199-6900","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T01:15:42Z","timestamp":1615425342000},"page":"246-253","source":"Crossref","is-referenced-by-count":4,"title":["Intraoperatives Floppy Iris Syndrom (IFIS) bei Tamsulosineinnahme"],"prefix":"10.1055","volume":"53","author":[{"given":"Eileen","family":"Bigdon","sequence":"additional","affiliation":[{"name":"Augenzentrum Schleswig-Holstein, Neum\u00fcnster"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Casagrande","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, Opthalmology, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin Stephan","family":"Spitzer","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, Opthalmology, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Hassenstein","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf, Opthalmology, Hamburg"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,3,10]]},"reference":[{"key":"ref1","first-page":"1711","article-title":"Intraoperatives Floppy-Iris-Syndrom im Zusammenhang mit Tamsulosin","volume":"37","author":"Arzneimittelkommission der deutschen \u00c4rzteschaft","year":"2020","journal-title":"Deustches \u00c4rztebaltt"},{"issue":"19","key":"ref3","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1001\/jama.2009.683","article-title":"Association Between Tamsulosin and Serious Ophthalmic Adverse Events in Older Men Following Cataract Surgery","volume":"301","author":"M D Bell","year":"2009","journal-title":"JAMA"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1016\/j.jcrs.2007.03.032.","article-title":"Intraoperative floppy iris syndrom associated with alpha1-adrenoreceptors: comparism of Tamsulosin und Alfuzosin","volume":"33","author":"M C Blouin","year":"2007","journal-title":"J Catraract Refract Surg"},{"issue":"04","key":"ref5","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.ophtha.2018.11.028.","article-title":"Evolution in the Risk of Cataract Surgical Complications among Patients Exposed to Tamsulosin: A Population-Based Study","volume":"126","author":"R J Campbell","year":"2019","journal-title":"Ophthalmology"},{"issue":"04","key":"ref6","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.jcrs.2005.02.027.","article-title":"Intraoperative floppy iris syndrome associated with tamsulosin","volume":"31","author":"D F Chang","year":"2005","journal-title":"J Cataract Refract Surg"},{"issue":"07","key":"ref7","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1016\/j.jcrs.2008.04.014.","article-title":"Clinical experience with intraoperative floppy-iris syndrome. 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