{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T07:34:43Z","timestamp":1771054483021,"version":"3.50.1"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatr Prax"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Ziel Untersuchung der diagnostischen Validit\u00e4t der Skala zur Erfassung von Autismusspektrumst\u00f6rung bei Minderbegabten (SEAS-M).<\/jats:p><jats:p>\n          Methodik Unverblindete Anwendung der SEAS-M in einer klinisch-psychiatrischen Stichprobe Erwachsener mit Intelligenzminderung (IM; N\u200a=\u200a109) und Autismusverdacht.<\/jats:p><jats:p>\n          Ergebnisse Sensitivit\u00e4t von 89\u200a%, Spezifit\u00e4t von 62\u200a%, Fl\u00e4che unter der Kurve (AUC) von 0,83 bei einem Grenzwert von 10. Alter, Geschlecht und Schwere der IM sind ohne Einfluss auf den Gesamtwert. Ausgewogenere diagnostische Validit\u00e4t bei leichter bis mittelgradiger IM (Sensitivit\u00e4t\/ Spezifit\u00e4t: 85\u200a%\/73\u200a%) als bei schwerer bis schwerster IM (93\u200a%\/42\u200a%). Konvergente Validit\u00e4t mit anderen Autismusskalen (r\u200a=\u200a0,3\u20130,6), fehlende Korrelationen (divergente Validit\u00e4t) mit Skalen f\u00fcr Problemverhalten.<\/jats:p><jats:p>\n          Schlussfolgerung Die SEAS-M ist ein Screeninginstrument zur Autismusdiagnostik bei Erwachsenen mit leichter bis mittelgradiger IM, wobei die fehlende Verblindung zu einer \u00dcbersch\u00e4tzung der diagnostischen Validit\u00e4t gef\u00fchrt haben kann.<\/jats:p>","DOI":"10.1055\/a-1202-2967","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T22:50:19Z","timestamp":1594680619000},"page":"37-43","source":"Crossref","is-referenced-by-count":3,"title":["Validierung der Skala zur Erfassung von Autismusspektrumst\u00f6rung bei Minderbegabten (SEAS-M) an einer klinisch-psychiatrischen Stichprobe Erwachsener"],"prefix":"10.1055","volume":"48","author":[{"given":"Julia","family":"B\u00f6hm","sequence":"additional","affiliation":[{"name":"Ev. Krankenhaus K\u00f6nigin Elisabeth Herzberge, Abteilung f\u00fcr psychische Gesundheit bei intellektuellen Entwicklungsst\u00f6rungen"},{"name":"Freie Universit\u00e4t Berlin, Fakult\u00e4t f\u00fcr Erziehungswissenschaft und Psychologie, Zentrum f\u00fcr seelische Gesundheit"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hauke","family":"Hermann","sequence":"additional","affiliation":[{"name":"Ev. Krankenhaus K\u00f6nigin Elisabeth Herzberge, Abteilung f\u00fcr psychische Gesundheit bei intellektuellen Entwicklungsst\u00f6rungen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Melchers","sequence":"additional","affiliation":[{"name":"Klinikum Oberberg, Kreiskrankenhaus Gummersbach und Klinik Marienheide, Abteilung f\u00fcr Kinder- und Jugendpsychiatrie, Psychotherapie, Psychosomatik"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Sappok","sequence":"additional","affiliation":[{"name":"Ev. 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Klinisch-diagnostische Leitlinien","author":"H Dilling","year":"2011"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1203\/PDR.0b013e31819e7203","article-title":"Epidemiology of pervasive developmental disorders","volume":"65","author":"E Fombonne","year":"2009","journal-title":"Pediatr Res"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/j.ridd.2013.01.028","article-title":"Diagnosing autism in a clinical sample of adults with intellectual disabilities: how useful are the ADOS and the ADI-R?","volume":"34","author":"T Sappok","year":"2013","journal-title":"Res Dev Disabil"},{"key":"ref4","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2013","edition":"5th"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579419000506","article-title":"Adoptees\u2019 responses to separation from, and reunion with, their adoptive parent at age 4 years is associated with long-term persistence of autism symptoms following early severe institutional deprivation","author":"E Sonuga-Barke","year":"2019","journal-title":"Dev Psychopathol"},{"key":"ref6","first-page":"1","article-title":"Der Diagnostische Beobachtungsbogen f\u00fcr Autismus Spektrumst\u00f6rungen (DiBAS): Ein Screeninginstrument f\u00fcr Erwachsene mit Intelligenzminderung bei Autismusverdacht","volume":"41","author":"T Sappok","year":"2014","journal-title":"Psychiat Prax"},{"key":"ref7","volume-title":"Fragenbogen zur Sozialen Kommunikation \u2013 Autismusscreening","author":"S B\u00f6lte","year":"2006"},{"key":"ref8","volume-title":"Der Diagnostische Beobachtungsbogen f\u00fcr Autismus-Spektrum-St\u00f6rungen \u2013 Revidiert (DiBAS-R)","author":"T Sappok","year":"2015"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1343193","article-title":"Psychometrische Eigenschaften der Autismus-Checkliste (ACL) f\u00fcr erwachsene Menschen mit Intelligenzminderung","author":"T Sappok","year":"2014","journal-title":"Psychiat Prax"},{"key":"ref10","volume-title":"Skala zur Erfassung von Autismusspektrumst\u00f6rungen bei Minderbegabten (SEAS-M)","author":"D W Kraijer","year":"2003"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s10803-005-5040-0","article-title":"The PDD-MRS: An Instrument for Identification of Autism Spectrum Disorders in Persons with Mental Retardation","volume":"35","author":"D W Kraijer","year":"2005","journal-title":"J Autism Dev Disord"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-017-3416-6","article-title":"Psychometric Properties of Spanish Adaption of the PDD-MRS Scale in Adults with Intellectual Developmental Disorders: The EVTEA-DI Scale","author":"M J Cortes","year":"2017","journal-title":"J Autism Dev Disord"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF02211841","article-title":"Autism diagnostic observation schedule: A standardized observation of communicative and social behaviour","volume":"19","author":"C Lord","year":"1989","journal-title":"J Autism Dev Disord"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/BF02172145","article-title":"Autism diagnostic interview revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders","volume":"24","author":"C Lord","year":"1994","journal-title":"J Autism Dev Disord"},{"key":"ref15","volume-title":"ADI-R. Diagnostisches Interview f\u00fcr Autismus \u2013 Revidiert","author":"S B\u00f6lte","year":"2006"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2015.05.011","article-title":"Music-based autism diagnostics (MUSAD) \u2013 A newly developed diagnostic measure for adults with intellectual developmental disabilities suspected of autism","author":"T Bergmann","journal-title":"Res Dev Disabil"},{"key":"ref17","first-page":"485","article-title":"The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects","volume":"89","author":"M G Aman","year":"1985","journal-title":"Am J Ment Defic"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1176\/ajp.146.8.1081b","article-title":"The modified overt aggression scale","volume":"146","author":"D W Knoedler","year":"1989","journal-title":"American Journal of Psychiatry"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1017\/S0033291700049175","article-title":"The disability assessment schedule: a brief screening device for use with mentally retarded","volume":"12","author":"N Holmes","year":"1982","journal-title":"Psychol med"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00797324","article-title":"Evaluation of an adaptive behaviour classification for mentally retarded adults","volume":"28","author":"W Meins","year":"1993","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"ref21","first-page":"173","article-title":"Screening for developmental and behavioural problems","volume":"11","author":"F P Glascoe","year":"2005","journal-title":"Dev Disabil Res Rev"},{"key":"ref22","volume-title":"Analysis of Biomarker Data: A Practical Guide","author":"S W Looney","year":"2015"},{"key":"ref23","volume-title":"Statistical power analysis for the behavioral sciences","author":"J Cohen","year":"1988"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1186\/2040-2392-4-13","article-title":"Autism in DSM-5: progress and challenges","author":"F R Volkmar","year":"2013","journal-title":"Mol Autism"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1055\/s-0031-1273382","article-title":"Die Bedeutung des emotionalen Entwicklungsniveaus bei der psychiatrischen Behandlung von Menschen mit geistiger Behinderung","volume":"80","author":"T Sappok","year":"2012","journal-title":"Fortschr Neurol Psyc"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s10803-019-04302-8","article-title":"The Adapted ADOS: A New Module Set for the Assessment of Minimally Verbal Adolescents and Adults","volume":"50","author":"V H Bal","year":"2020","journal-title":"J Autism Dev Disord"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-017-3336-5","article-title":"Diagnostic validity of the DiBAS-R and the impact of level of functioning","author":"M Heinrich","year":"2017","journal-title":"J Autism Dev Disord"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1007\/s10803-010-1157-x","article-title":"Diagnosing autism spectrum disorders in adults: The use of Autism Diagnostic Observation Schedule (ADOS) module 4","volume":"41","author":"J A Bastiaansen","year":"2011","journal-title":"J Autism Dev Disord"},{"key":"ref29","volume-title":"AWMF-Leitlinie Autismus-Spektrum-St\u00f6rungen im Kindes-, Jugend- und Erwachsenenalter","year":"2016"}],"container-title":["Psychiatrische Praxis"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1202-2967.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T23:52:05Z","timestamp":1609804325000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1202-2967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,13]]},"references-count":29,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2021,1,4]]},"published-print":{"date-parts":[[2021,1]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1202-2967","relation":{},"ISSN":["0303-4259","1439-0876"],"issn-type":[{"value":"0303-4259","type":"print"},{"value":"1439-0876","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,13]]}}}