{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T07:35:46Z","timestamp":1648798546455},"reference-count":6,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ein 33-j\u00e4hriger Mann stellte sich wegen langsam progredienter Luftnot vor. Bei der Untersuchung fielen ein Pleuraerguss rechts, Lymph\u00f6dem linker Unterschenkel und Fu\u00df und fleckige, landkartenartige Hautver\u00e4nderungen auf. Bei der Pleurapunktion rechts konnte ein chyl\u00f6ser Erguss abgelassen werden. In der Ganzk\u00f6rper-MRT war der Pleuraerguss rechts nachweisbar, eine Vermehrung der Lymphgef\u00e4\u00dfe inguinal, parailiakal und paraaortal und prominente Chylusgef\u00e4\u00dfe. Eine oss\u00e4re Beteiligung lag nicht vor. Der Ductus thoracicus abdominalis war bis auf 3\u200amm erweitert. Wir stellten die Diagnose einer generalisierten lymphatischen Anomalie (GLA) \u2013 Lymphangiomatose. Die GLA ist eine seltene Erkrankung unbekannter Ursache mit Fehlentwicklung des lymphatischen Systems. Thorakal f\u00e4llt eine GLA oft durch die Entwicklung von chyl\u00f6sen Pleuraerg\u00fcssen auf. Es k\u00f6nnen aber auch viele andere Organe betroffen sein. Die Therapie besteht meist in einer symptomatischen Behandlung und dem Versuch, den Progress der Erkrankung zu verlangsamen.<\/jats:p>","DOI":"10.1055\/a-1207-1937","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T22:59:02Z","timestamp":1595631542000},"page":"138-141","source":"Crossref","is-referenced-by-count":0,"title":["Lymphangiomatose \u2212 seltene Ursache eines Pleuraergusses"],"prefix":"10.1055","volume":"75","author":[{"given":"M.","family":"Uhlenbruch","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pneumologie, Kardiologie und internistische Intensivmedizin, Florence Nightingale Krankenhaus, Kaiserswerther Diakonie, D\u00fcsseldorf"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Keymel","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kardiologie, Pneumologie und Angiologie, Medizinische Fakult\u00e4t, Universit\u00e4tsklinikum D\u00fcsseldorf"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Pneumologie, Kardiologie und internistische Intensivmedizin, Florence Nightingale Krankenhaus, Kaiserswerther Diakonie, D\u00fcsseldorf"},{"name":"Klinik f\u00fcr Kardiologie, Pneumologie und Angiologie, Medizinische Fakult\u00e4t, Universit\u00e4tsklinikum D\u00fcsseldorf"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1183\/16000617.0018-2016","article-title":"Thoracic involvement in generalised lymphatic anomaly (or lymphangiomatosis)","volume":"25","author":"F Luisi","year":"2016","journal-title":"European Respiratory Review"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1542\/peds.2014-3673","article-title":"Vascular anomalies classification: recommendations from the International Society for the Study of Vascular Anomalies","volume":"136","author":"M Wassef","year":"2015","journal-title":"Pediatrics"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.crad.2005.03.006","article-title":"Diagnostic value of bronchoscopy, CT and transbronchial biopsies in diffuse pulmonary lymphangiomatosis: Case report and review of the literature","volume":"60","author":"L El Hajj","year":"2005","journal-title":"Clin Radiol"},{"key":"ref4","first-page":"31","article-title":"Diffuse pulmonary lymphangiomatosis: imaging findings","volume":"11","author":"E Yekeler","year":"2005","journal-title":"Diagn Interv Radiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.ejrad.2009.10.021","article-title":"Assessment of the lymphatic system in patients with diffuse lymphangiomatosis by magnetic resonance imaging","volume":"80","author":"C Lohrmann","year":"2011","journal-title":"Eur J Radiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"e129","DOI":"10.1016\/j.mayocp.2014.05.020","article-title":"Multifocal infiltrative lymphangiomatosis in a child and successful treatment with sirolimus","volume":"89","author":"A Bassi","year":"2014","journal-title":"Mayo Clin Proc"}],"container-title":["Pneumologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1207-1937.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T05:09:43Z","timestamp":1613279383000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1207-1937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,24]]},"references-count":6,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2021,2,12]]},"published-print":{"date-parts":[[2021,2]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1207-1937","relation":{},"ISSN":["0934-8387","1438-8790"],"issn-type":[{"value":"0934-8387","type":"print"},{"value":"1438-8790","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,24]]}}}