{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T16:22:48Z","timestamp":1649089368850},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dtsch Med Wochenschr"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Anamnese\u2002Eine 39-j\u00e4hrige Patientin wird wegen pl\u00f6tzlicher ausgepr\u00e4gter Belastungsdyspnoe unter dem V.\u200aa. eine Lungenarterienembolie zugewiesen. Sie berichtet zudem \u00fcber eine gerade abgeschlossene Kinderwunschbehandlung.<\/jats:p><jats:p>\n          Untersuchungen und Diagnose\u2002Bei klinisch gutem Allgemeinzustand finden sich laborchemisch eine deutliche Erh\u00f6hung der D-Dimere und des hCGs, sonografisch ein ausgepr\u00e4gter Aszites, ein gro\u00dfer rechtsseitiger Pleuraerguss sowie multizystische, deutlich vergr\u00f6\u00dferte Ovarien. In Zusammenschau mit der Anamnese wird die Diagnose eines ovariellen Hyperstimulationssyndroms (OHSS) gestellt. Diese Diagnose wird durch die Gyn\u00e4kologen best\u00e4tigt und als Grad II\u2013III (moderat bis schwer) klassifiziert.<\/jats:p><jats:p>\n          Therapie und Verlauf\u2002Bis auf eine Thromboembolie-Prophylaxe mit Certoparin 3000\u200aIE\/d wird keine Therapie durchgef\u00fchrt; die Erkrankung verl\u00e4uft selbstlimitierend.<\/jats:p><jats:p>\n          Schlussfolgerung\u2002Das OHSS ist prim\u00e4r ein gyn\u00e4kologisches Krankheitsbild, dennoch k\u00f6nnen auch Internisten \u00fcber die Leitsymptome Belastungsdyspnoe oder abdomineller Schmerz damit in Kontakt kommen. Fr\u00fch erkannt sind die Symptome gut zu behandeln und schwere Verl\u00e4ufe k\u00f6nnen meist verhindert werden. In diesem Fall konnten Anamnese und Sonografie die initiale Verdachtsdiagnose einer Lungenarterienembolie widerlegen.<\/jats:p>","DOI":"10.1055\/a-1219-9780","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T04:40:37Z","timestamp":1605674437000},"page":"1697-1700","source":"Crossref","is-referenced-by-count":0,"title":["Pl\u00f6tzliche Belastungsdyspnoe bei einer jungen Frau \u2013 internistisch-gyn\u00e4kologisches Grenzgebiet in der Notaufnahme"],"prefix":"10.1055","volume":"145","author":[{"given":"Lisa","family":"Mehl","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, Albertinen-Krankenhaus Hamburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Donner","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Gyn\u00e4kologie, Albertinen-Krankenhaus Hamburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guntram","family":"Lock","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Innere Medizin, Albertinen-Krankenhaus Hamburg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/humupd\/dmn008","article-title":"Targeting the vascular endothelial growth factor system to prevent ovarian hyperstimulation syndrome","volume":"14","author":"S R Soares","year":"2008","journal-title":"Hum Reprod Update"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/humupd\/3.3.255","article-title":"The role of vascular endothelial growth factor and interleukins in the pathogenesis of severe ovarian hyperstimulation syndrome","volume":"3","author":"B Rizk","year":"1997","journal-title":"Hum Reprod Update"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1055\/s-0033-1358128","article-title":"Das ovarielle \u00dcberstimulationssyndrom- OHSS","volume":"9","author":"C Keck","year":"2015","journal-title":"Frauenheilkunde up2date"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1093\/humrep\/deg302","article-title":"Prediction of ovarian hyperstimulation syndrome: why predict if we can prevent!","volume":"18","author":"S Kol","year":"2003","journal-title":"Hum Reprod"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1093\/humrep\/deu175","article-title":"Assisted reproductive technology in Europe, 2010: results generated from European registers by ESHREdagger","volume":"29","author":"M S Kupka","year":"2014","journal-title":"Hum Reprod"},{"key":"ref8","first-page":"CD008046","article-title":"Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in antagonist-assisted reproductive technology","volume":"10","author":"M A Youssef","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/j.fertnstert.2014.08.013","article-title":"Ovarian response to recombinant human follicle-stimulating hormone: a randomized, antimullerian hormone-stratified, dose-response trial in women undergoing in vitro fertilization\/intracytoplasmic sperm injection","volume":"102","author":"J C Arce","year":"2014","journal-title":"Fertil Steril"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1055\/s-2002-36363","article-title":"Von der Pathophysiologie und Pr\u00e4vention des ovariellen \u00dcberstimulationssyndrom (OHSS) bis zur stadiengerechten Therapie","volume":"62","author":"S Kissler","year":"2002","journal-title":"Geburtsh Frauenheilk"}],"container-title":["DMW - Deutsche Medizinische Wochenschrift"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1219-9780.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T04:41:20Z","timestamp":1605674480000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1219-9780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":8,"journal-issue":{"issue":"23","published-online":{"date-parts":[[2020,11,17]]},"published-print":{"date-parts":[[2020,11]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1219-9780","relation":{},"ISSN":["0012-0472","1439-4413"],"issn-type":[{"value":"0012-0472","type":"print"},{"value":"1439-4413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11]]}}}