{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T22:43:41Z","timestamp":1747694621235},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["An\u00e4sthesiol Intensivmed Notfallmed Schmerzther"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Etwa ein Drittel aller Patienten, die sich einem operativen Eingriff unterziehen, nehmen chronisch Psychopharmaka ein. Neben Depressionen und Psychosen stellen chronische Schmerzen sowie Angst- und Panikst\u00f6rungen die h\u00e4ufigsten Indikationen dar. In den vergangenen 30 Jahren stieg die H\u00e4ufigkeit der Verordnung von Psychopharmaka um das 7-Fache. Fast alle Psychopharmaka interagieren mit Medikamenten, die perioperativ h\u00e4ufig gegeben werden, beispielsweise mit 5-HT3-Antagonisten, Sympathomimetika oder Opioiden. Einige der Medikamente weisen eine enge therapeutische Breite auf und nicht alle Medikamente k\u00f6nnen perioperativ pausiert werden. Im Rahmen der pr\u00e4operativen Risikoevaluation ist daher eine Pr\u00fcfung im Einzelfall notwendig. Der An\u00e4sthesist muss zudem bei Gabe bestimmter Medikamente w\u00e4hrend der Narkose besondere Vorsicht walten lassen oder ganz auf diese verzichten.<\/jats:p><jats:p>Bei der Therapie vieler neurologischer Erkrankungen stellen Medikamente die zentrale S\u00e4ule dar. H\u00e4ufig begegnen dem An\u00e4sthesisten Patienten mit einer Epilepsie, mit Morbus Parkinson oder mit einer Myasthenia gravis, die eine entsprechende medikament\u00f6se Therapie erhalten. Das perioperative Pausieren der Medikamente l\u00e4sst zumeist eine Befundverschlechterung der neurologischen Grunderkrankung bef\u00fcrchten. Auf die m\u00f6glichst rasche postoperative Einnahme der Dauermedikation ist daher besonderer Wert zu legen.<\/jats:p>","DOI":"10.1055\/a-1226-4756","type":"journal-article","created":{"date-parts":[[2021,10,27]],"date-time":"2021-10-27T00:31:59Z","timestamp":1635294719000},"page":"691-702","source":"Crossref","is-referenced-by-count":3,"title":["Perioperatives Management psychiatrischer und neurologischer Dauermedikation"],"prefix":"10.1055","volume":"56","author":[{"given":"Melanie","family":"Bischoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Redel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,10,26]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/BF03020484","article-title":"Antidepressant treatment for chronic depressed patiens should not be discontinued prior to anesthesia","volume":"49","author":"A Kudoh","year":"2002","journal-title":"Can J Anesth"},{"key":"ref2","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-59046-1","volume-title":"Arzneimittelverordnungsreport 2019","author":"U Schwabe","year":"2019"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4103\/0019-5049.93337","article-title":"Psychiatric patient and anaesthesia","volume":"56","author":"J P Attri","year":"2012","journal-title":"Indian J Anaesth"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1055\/s-0043-111784","article-title":"Pr\u00e4operative Evaluation erwachsener Patienten vor elektiven, nicht herz-thoraxchirurgischen Eingriffen. 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