{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T02:44:32Z","timestamp":1648694672874},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Wiedererlangung einer Stimmfunktion nach Laryngektomie ist ein zentrales Element f\u00fcr die postoperative Lebensqualit\u00e4t. Dazu haben sich Stimmprothesen als probates Mittel etabliert. H\u00e4ufige Prothesenwechsel stellen f\u00fcr einige Patienten jedoch eine teils gro\u00dfe Belastung dar, sodass ein besseres Verst\u00e4ndnis der \u00c4tiologie der Stimmprothesen- und Stimmprothesenlagerinsuffizienz ben\u00f6tigt wird.<\/jats:p><jats:p>\n          Material und Methoden\u2002Es erfolgte die retrospektive Auswertung klinischer Daten von 58 Patienten nach Laryngektomie. Des Weiteren wurde pr\u00e4- und postoperative CT-Bildgebung von 22 Patienten mit der Frage nach Stenosen im Bereich des Neopharynx verglichen.<\/jats:p><jats:p>\n          Ergebnisse\u2002In dem untersuchten Kollektiv wurde bei 40 Patienten mindestens ein Wechsel der Stimmprothese durchgef\u00fchrt; es zeigte sich ein medianes Wechselintervall von 235\u00a0Tagen. Patienten nach adjuvanter Radiochemotherapie zeigten signifikant k\u00fcrzere Wechselintervalle als nach adjuvanter Radiotherapie (p\u200a=\u200a0,002). Des Weiteren konnte eine gastro\u00f6sophageale Refluxerkrankung (GERD) als Risikofaktor f\u00fcr k\u00fcrzere Stimmprothesenwechselintervalle nachgewiesen werden (p\u200a=\u200a0,04).<\/jats:p><jats:p>Klinisch relevante Stenosen zeigten sich bei 17 Patienten (42,5\u200a%), davon wurden 14 Patienten (82\u200a%) mittels Bougierung therapiert und zeigten keine verk\u00fcrzte Stimmprothesenverweildauer (p\u200a=\u200a0,892).<\/jats:p><jats:p>\n          Schlussfolgerung\u2002GERD stellt einen Risikofaktor f\u00fcr h\u00e4ufige Stimmprotheseninsuffizienz dar und sollte daher nach Laryngektomie suffizient therapiert werden. Mit zunehmender Eskalation der adjuvanten Therapie zeigt sich ein k\u00fcrzeres Wechselintervall.<\/jats:p><jats:p>Stenosen werden h\u00e4ufig nach Laryngektomie beobachtet, stellen aber unter Therapie keinen alleinigen Risikofaktor f\u00fcr eine kurze Stimmprothesenverweildauer dar.<\/jats:p>","DOI":"10.1055\/a-1226-6927","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T22:57:16Z","timestamp":1598569036000},"page":"788-794","source":"Crossref","is-referenced-by-count":0,"title":["GERD und adjuvante Radiochemotherapie pr\u00e4disponieren f\u00fcr\u00a0rezidivierende Stimmprotheseninsuffizienz"],"prefix":"10.1055","volume":"99","author":[{"given":"Daniel","family":"Jira","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Klinikum rechts der Isar der TU M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Pickhard","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Klinikum rechts der Isar der TU M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Mair","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr An\u00e4sthesiologie und Intensivmedizin, Klinikum\u00a0rechts der Isar der TU M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaojun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Klinikum rechts der Isar der TU M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Wollenberg","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Klinikum rechts der Isar der TU M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Maria Stefanie","family":"Buchberger","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Hals-, Nasen- und Ohrenheilkunde, Klinikum rechts der Isar der TU M\u00fcnchen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"key":"ref1","volume-title":"Kopf-Hals-Malignome","author":"G Mast","year":"2014"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1001\/jamaoto.2014.1671","article-title":"Survival outcomes in advanced laryngeal cancer","volume":"140","author":"U C Megwalu","year":"2014","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/1460-6984.12148","article-title":"Quality of life after total laryngectomy: functioning, psychological well-being and self-efficacy","volume":"50","author":"A Perry","year":"2015","journal-title":"Int J Lang Commun Disord"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00405-017-4790-6","article-title":"Objective and subjective voice outcomes after total laryngectomy: a systematic review","volume":"275","author":"K E van Sluis","year":"2018","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1177\/0194599815601026","article-title":"Increased Pharyngeal Reflux in Patients Treated for Laryngeal Cancer: A Pilot Study","volume":"153","author":"B LeBlanc","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/s00405-007-0536-1","article-title":"The impact of radiotherapy and GERD on in situ lifetime of indwelling voice prostheses","volume":"265","author":"P Boscolo-Rizzo","year":"2008","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref9","first-page":"508","article-title":"Management of complications after prosthetic voice rehabilitation","volume":"48","author":"A Neumann","year":"2000","journal-title":"HNO"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1159\/000477970","article-title":"Comparison between Primary and Secondary Tracheoesophageal Puncture Prosthesis: A\u00a0Systematic Review","volume":"79","author":"J C Barauna Neto","year":"2017","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/coa.13138","article-title":"Primary versus secondary tracheoesophageal puncture for voice rehabilitation in laryngectomy patients: A systematic review","volume":"43","author":"K Luu","year":"2018","journal-title":"Clin Otolaryngol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1002\/hed.24727","article-title":"Total laryngectomy with primary tracheoesophageal puncture: Intraoperative versus delayed voice prosthesis placement","volume":"39","author":"R A Robinson","year":"2017","journal-title":"Head Neck"},{"key":"ref13","first-page":"497","article-title":"Post-laryngectomy voice rehabilitation: comparison of primary and secondary tracheoesophageal puncture","volume":"15","author":"D Guttman","year":"2013","journal-title":"Isr Med Assoc J"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/hed.21399","article-title":"Enlarged tracheoesophageal puncture after total laryngectomy: a systematic review and meta-analysis","volume":"33","author":"K A Hutcheson","year":"2011","journal-title":"Head Neck"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00405-014-3394-7","article-title":"The development and treatment of periprosthetic leakage after prosthetic voice restoration. A literature review and personal experience part I: the development of periprosthetic leakage","volume":"272","author":"K J Lorenz","year":"2015","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s00405-014-3393-8","article-title":"The development and treatment of periprosthetic leakage after prosthetic voice restoration: a literature review and personal experience. Part II: conservative and surgical management","volume":"272","author":"K J Lorenz","year":"2015","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.anorl.2012.03.008","article-title":"Management of voice prosthesis leakage with Blom-Singer large esophage and tracheal flange voice prostheses","volume":"130","author":"O Choussy","year":"2013","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s00106-020-00853-w","article-title":"Epithetische Versorgung im Kopf-Hals-Bereich","volume":"68","author":"P A Federspil","year":"2020","journal-title":"HNO"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1002\/lary.27027","article-title":"Treatment of tracheoesophageal fistula after laryngectomy by a customized tracheal prosthesis","volume":"128","author":"S A Mueller","year":"2018","journal-title":"Laryngoscope"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/hed.21833","article-title":"Composition and architecture of biofilms on used voice prostheses","volume":"34","author":"K J Buijssen","year":"2012","journal-title":"Head Neck"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.gtc.2016.09.009","article-title":"The Esophageal and Gastric Microbiome in Health and Disease","volume":"46","author":"R H Hunt","year":"2017","journal-title":"Gastroenterol Clin North Am"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1002\/lary.27072","article-title":"Esophagram findings in cervical esophageal stenosis: A case-controlled quantitative analysis","volume":"128","author":"J West","year":"2018","journal-title":"Laryngoscope"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1038\/ajg.2011.348","article-title":"Endoscopic management of difficult or recurrent esophageal strictures","volume":"106","author":"L R de Wijkerslooth","year":"2011","journal-title":"Am J Gastroenterol"}],"container-title":["Laryngo-Rhino-Otologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1226-6927.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T02:56:51Z","timestamp":1603853811000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1226-6927"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,27]]},"references-count":21,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,10,27]]},"published-print":{"date-parts":[[2020,11]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1226-6927","relation":{},"ISSN":["0935-8943","1438-8685"],"issn-type":[{"value":"0935-8943","type":"print"},{"value":"1438-8685","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,27]]}}}