{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:34:19Z","timestamp":1790249659714,"version":"4.1.0"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2002Conventional endoscopic resection of lesions affecting the appendiceal orifice is difficult. Endoscopic full-thickness resection (EFTR) is a novel technique in interventional endoscopy. As EFTR near the appendiceal orifice is associated with a subtotal appendectomy, it remains unclear whether the risk of developing appendicitis is increased. We conducted a retrospective analysis of lesions involving the appendiceal orifice treated by EFTR.<\/jats:p><jats:p>\n          Methods\u2002This was a multicenter retrospective analysis of patients (n\u200a=\u200a50) treated with EFTR for lesions involving the appendiceal orifice between 2014 and 2019.\u200aThe objective was to evaluate the occurrence of appendicitis.<\/jats:p><jats:p>\n          Results\u2002Acute appendicitis occurred in seven patients (14\u200a%) during follow-up.\u200aConservative treatment was sufficient in four cases, and three patients underwent appendectomy.<\/jats:p><jats:p>\n          Conclusions\u2002EFTR of lesions involving the appendiceal orifice may be associated with an imminent risk of developing appendicitis and a consecutive need for appendectomy. Patients should be informed about this specific risk prior to resection. It is unclear why some patients develop appendicitis while the majority remains asymptomatic.<\/jats:p>","DOI":"10.1055\/a-1227-4555","type":"journal-article","created":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T22:41:17Z","timestamp":1599518477000},"page":"424-428","source":"Crossref","is-referenced-by-count":33,"title":["Risk of appendicitis after endoscopic full-thickness resection of lesions involving the appendiceal orifice: a retrospective analysis"],"prefix":"10.1055","volume":"53","author":[{"given":"Simone","family":"Schmidbaur","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik Ulm, Klinik f\u00fcr Innere Medizin I, Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Wannhoff","sequence":"additional","affiliation":[{"name":"Klinikum Ludwigsburg, Klinik f\u00fcr Innere Medizin, Gastroenterologie, H\u00e4mato-Onkologie, Pneumologie, Diabetologie und Infektiologie, Ludwigsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Walter","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik Ulm, Klinik f\u00fcr Innere Medizin I, Ulm, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Meier","sequence":"additional","affiliation":[{"name":"Klinikum Ludwigsburg, Klinik f\u00fcr Innere Medizin, Gastroenterologie, H\u00e4mato-Onkologie, Pneumologie, Diabetologie und Infektiologie, Ludwigsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Kliniken des Landkreises Neumarkt i.d. OPf., Neumarkt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Meining","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum W\u00fcrzburg, Medizinische Klinik und Poliklinik II, Gastroenterologie, W\u00fcrzburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karel","family":"Caca","sequence":"additional","affiliation":[{"name":"Klinikum Ludwigsburg, Klinik f\u00fcr Innere Medizin, Gastroenterologie, H\u00e4mato-Onkologie, Pneumologie, Diabetologie und Infektiologie, Ludwigsburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,9,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1136\/gutjnl-2016-313677","article-title":"Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in various indications","volume":"67","author":"A 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Switzerland","volume":"6","author":"P Aepli","year":"2018","journal-title":"United European Gastroenterol J"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"3483","DOI":"10.1002\/cncr.24320","article-title":"A uniform residual tumor (R) classification","volume":"115","author":"C Wittekind","year":"2009","journal-title":"Cancer"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"E1112","DOI":"10.1055\/a-0635-0911","article-title":"Endoscopic full-thickness resection of polyps involving the appendiceal orifice: a prospective observational case study","volume":"06","author":"M Bronzwaer","year":"2018","journal-title":"Endosc Int Open"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.1007\/s00464-017-5461-9","article-title":"Hybrid endoscopic mucosal resection and full-thickness resection: a new approach for resection of large non-lifting colorectal adenomas (with video)","volume":"31","author":"B Meier","year":"2017","journal-title":"Surg Endosc"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"E622","DOI":"10.1055\/a-0589-9850","article-title":"Full-thickness resection with an over-the-scope device: possible translocation of adenoma tissue in a case of an incomplete resection at the appendix","volume":"6","author":"F L Dumoulin","year":"2018","journal-title":"Endosc Int 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