{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T20:14:08Z","timestamp":1767903248684,"version":"3.49.0"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>\n            Purpose\u2002To assess the effectiveness of pain management with superior hypogastric plexus block (SHPB) compared to epidural anesthesia (EDA) in women requiring uterine artery embolization (UAE).<\/jats:p><jats:p>\n            Materials and Methods\u2002In this retrospective, single-center, non-randomized trial we included 79 women with symptomatic uterine fibroids who were scheduled for percutaneous, transcatheter UAE. According to their informed decision, the women were assigned to two different approaches of pain management including either SHPB or EDA. The effectiveness outcome measure was patient reported pain using a numeric rating scale ranging from 1 to 10. The pain score was assessed at UAE, 2 hours thereafter, and at subsequent intervals of 6\u00a0hours up to 36 hours after intervention.<\/jats:p><jats:p>\n            Results\u2002Treatment groups did not differ significantly regarding age, pain score for regular menstrual cramps, uterine fibroid size, location, and symptoms of uterine fibroids. During UAE and up to 6 hours thereafter, women who received SHPB experienced stronger pain than those who received EDA (mean pain score during UAE: 3.3 vs. 1.5, p\u200a&lt;\u200a0.001; at 2\u00a0hours: 4.4 vs. 2.8, p\u200a=\u200a0.012; at 6 hours: 4.4 vs. 2.6, p\u200a=\u200a0.021). The maximum pain level was 5.8\u200a\u00b1\u200a2.9 with SHPB and 4.5\u200a\u00b1\u200a2.9 with EDA (p\u200a=\u200a0.086). Women with a history of severe menorrhagia tended to experience worse pain than those without (regression coefficient 2.5 [95\u200a% confidence interval \u20130.3 to 5.3], p\u200a=\u200a0.076).<\/jats:p><jats:p>\n            Conclusion\u2002Among women who underwent UAE, pain management including SHPB resulted in stronger pain during and after the procedure than pain treatment including EDA.<\/jats:p><jats:p>\n            Key Points:\n          <\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-1231-5649","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T22:48:55Z","timestamp":1599173335000},"page":"289-297","source":"Crossref","is-referenced-by-count":9,"title":["Effectiveness of Superior Hypogastric Plexus Block for Pain Control Compared to Epidural Anesthesia in Women Requiring Uterine Artery Embolization for the Treatment of Uterine Fibroids \u2013 A\u00a0Retrospective Evaluation"],"prefix":"10.1055","volume":"193","author":[{"given":"Amer","family":"Malouhi","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle f\u00fcr Radiologie, Universit\u00e4tsklinikum Jena IDIR, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rene","family":"Aschenbach","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle f\u00fcr Radiologie, Universit\u00e4tsklinikum Jena IDIR, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Erbe","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle f\u00fcr Radiologie, Universit\u00e4tsklinikum Jena IDIR, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zbigniew","family":"Owsianowski","sequence":"additional","affiliation":[{"name":"Gyn\u00e4kologie & onkologische Gyn\u00e4kologie, Klinik Hallerwiese, Nurnberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Ru\u00dfwurm","sequence":"additional","affiliation":[{"name":"Abteilung f\u00fcr An\u00e4sthesie, Hufeland Klinikum GmbH, Bad\u00a0Langensalza, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo B.","family":"Runnebaum","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Frauenheilkunde und Fortpflanzungsmedizin, Universit\u00e4tsklinikum, Jean, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Teichgr\u00e4ber","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diagnostische und Interventionelle f\u00fcr Radiologie, Universit\u00e4tsklinikum Jena IDIR, Jena, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,9,3]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1056\/NEJMoa062003","article-title":"Uterine-artery embolization versus surgery for symptomatic uterine fibroids","volume":"356","author":"R D Edwards","year":"2007","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"745 e741","DOI":"10.1016\/j.ajog.2016.06.051","article-title":"Uterine artery embolization vs hysterectomy in the treatment of symptomatic uterine fibroids: 10-year outcomes from the randomized EMMY trial","volume":"215","author":"A M de Bruijn","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1007\/s00330-009-1481-8","article-title":"Pain after uterine fibroid embolisation is associated with the severity of myometrial ischaemia on magnetic resonance imaging","volume":"19","author":"A Ruuskanen","year":"2009","journal-title":"European radiology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/pme.12106","article-title":"Efficacy of the anterior ultrasound-guided superior hypogastric plexus neurolysis in pelvic cancer pain in advanced gynecological cancer patients","volume":"14","author":"S Mishra","year":"2013","journal-title":"Pain medicine (Malden, Mass)"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/1471-0528.14119","article-title":"Superior hypogastric plexus block as a new method of pain relief after abdominal hysterectomy: double-blind, randomised clinical trial of efficacy","volume":"124","author":"H Rapp","year":"2017","journal-title":"BJOG: an international journal of obstetrics and gynaecology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1148\/radiol.2018172714","article-title":"Superior Hypogastric Nerve Block as Post-Uterine Artery Embolization Analgesia: A Randomized and Double-Blind Clinical Trial","volume":"289","author":"J Yoon","year":"2018","journal-title":"Radiology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/s00270-015-1118-z","article-title":"Superior Hypogastric Nerve Block to Reduce Pain After Uterine Artery Embolization: Advanced Technique and Comparison to Epidural Anesthesia","volume":"38","author":"C A Binkert","year":"2015","journal-title":"Cardiovascular and interventional radiology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1046\/j.1533-2500.2001.01017.x","article-title":"Blockade of the superior hypogastric plexus block for visceral pelvic pain","volume":"1","author":"H Bosscher","year":"2001","journal-title":"Pain practice: the official journal of World Institute of Pain"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.2147\/JPR.S134775","article-title":"Ganglion blocks as a treatment of pain: current perspectives","volume":"10","author":"O H Gunduz","year":"2017","journal-title":"Journal of pain research"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1097\/01.RVI.0000137406.09852.A4","article-title":"Superior hypogastric nerve block for pain control in outpatient uterine artery embolization","volume":"15","author":"P Rasuli","year":"2004","journal-title":"Journal of vascular and interventional radiology: JVIR"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1055\/s-0033-1359729","article-title":"Clinical and periprocedural pain management for uterine artery embolization","volume":"30","author":"E B Spencer","year":"2013","journal-title":"Seminars in interventional radiology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.4103\/0019-5049.79875","article-title":"Ropivacaine: A review of its pharmacology and clinical use","volume":"55","author":"G Kuthiala","year":"2011","journal-title":"Indian journal of anaesthesia"},{"key":"ref13","first-page":"156","article-title":"Outpatient uterine artery embolization for symptomatic fibroids: short- and long-term single institution-based outcomes","volume":"35","author":"P Rasuli","year":"2013","journal-title":"Journal of obstetrics and gynaecology Canada: JOGC = Journal d\u2019obstetrique et gynecologie du Canada: JOGC"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1007\/s00270-014-0913-2","article-title":"A randomized, double-blind, placebo-controlled study of preemptive oral oxycodone with morphine patient-controlled anesthesia for postoperative pain management in patients undergoing uterine artery embolization for symptomatic uterine fibroids","volume":"37","author":"A H Konstantatos","year":"2014","journal-title":"Cardiovascular and interventional radiology"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"428 e421","DOI":"10.1016\/j.crad.2016.12.010","article-title":"Controlled-release oxycodone improves pain management after uterine artery embolisation for symptomatic fibroids","volume":"72","author":"G M Freire","year":"2017","journal-title":"Clinical radiology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.jmig.2008.05.012","article-title":"Pain relief by continuous intraperitoneal nebulization of ropivacaine during gynecologic laparoscopic surgery \u2013 a randomized study and review of the literature","volume":"15","author":"Y Kaufman","year":"2008","journal-title":"Journal of minimally invasive gynecology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00276-004-0301-8","article-title":"The anatomical relationship of the iliocava junction to the lumbosacral spine and the aortic bifurcation","volume":"27","author":"N Pirro","year":"2005","journal-title":"Surgical and radiologic anatomy: SRA"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/papr.12437","article-title":"Ultrasound-Guided Superior Hypogastric Plexus Block: A Cadaveric Feasibility Study with Fluoroscopic Confirmation","volume":"17","author":"M Gofeld","year":"2017","journal-title":"Pain practice: the official journal of World Institute of Pain"},{"key":"ref19","first-page":"4","article-title":"Time course of pain after uterine artery embolization for fibroid disease","volume":"7","author":"R L Worthington-Kirsch","year":"2002","journal-title":"Medscape women's health"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S1051-0443(07)61337-2","article-title":"Pain after uterine artery embolization for leiomyomata: can its severity be predicted and does severity predict outcome?","volume":"11","author":"A R Roth","year":"2000","journal-title":"Journal of vascular and interventional radiology: JVIR"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/00000542-200608000-00016","article-title":"Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy","volume":"105","author":"W Y Chou","year":"2006","journal-title":"Anesthesiology"}],"container-title":["R\u00f6Fo - Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1231-5649.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T23:40:38Z","timestamp":1613691638000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1231-5649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,3]]},"references-count":21,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2021,2,18]]},"published-print":{"date-parts":[[2021,3]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1231-5649","relation":{},"ISSN":["1438-9029","1438-9010"],"issn-type":[{"value":"1438-9029","type":"print"},{"value":"1438-9010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,3]]}}}