{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:11Z","timestamp":1787004851815,"version":"build-2736575974"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"10","license":[{"start":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T00:00:00Z","timestamp":1602028800000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background and study aims\u2002The etiology of idiopathic acute pancreatitis (IAP) should always be defined. Our aim was to compare the diagnostic value of endoscopic ultrasound (EUS) versus secretin-enhanced magnetic resonance cholangiopancreatography (S-MRCP) in patients with IAP.<\/jats:p>\n                  <jats:p>Patients and Methods\u2002Patients admitted to a single tertiary care University hospital with IAP were invited to participate in the study. Enrolled patients underwent EUS and S-MRCP in a single-blinded comparative study. EUS and S-MRCP were performed no sooner than 4 weeks after discharge. The diagnostic yield of EUS and S-MRCP and demographic variables were included in the analysis. Additional follow-up, results of subsequent serology, radiographic exams, and relevant histological analysis were considered in determination of the final diagnosis.<\/jats:p>\n                  <jats:p>Results\u2002A total of 34 patients were enrolled; EUS was normal in six, cholelithiasis was defined in 15, choledocholithiasis in two, pancreas divisum in three, branch-type intraductal papillary mucinous tumor (IPMT) in three, and chronic pancreatitis in five. S-MRCP identified choledocholithiasis in one, divisum in four, branch-type IPMT in three, chronic pancreatitis in two; 24 subjects diagnosed as normal by S-MRCP. Diagnostic correlation between EUS and S-MRCP was slight (kappa\u200a=\u200a0.236, 95\u200a% confidence interval: 0.055\u20130.416). EUS provided a statistically significantly higher diagnostic yield than S-MRCP: 79.4\u200a% (CI95\u200a%: 65\u200a%\u201394\u200a%) vs 29.4\u200a% (CI95\u200a%: 13\u200a%\u201346\u200a%) (P\u200a=\u200a0.0002). The sensitivity, specificity, and positive and negative predictive values of EUS and S-MRCP were 90\u200a%, 80\u200a%, 96\u200a%, 57\u200a% and 33\u200a%, 100\u200a%, 100\u200a% and 16\u200a%, respectively.<\/jats:p>\n                  <jats:p>Conclusion\u2002The diagnostic yield of EUS is higher than S-MRCP in patients with IAP.<\/jats:p>","DOI":"10.1055\/a-1233-1849","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T02:03:05Z","timestamp":1604282585000},"page":"E1441-E1447","source":"Crossref","is-referenced-by-count":10,"title":["EUS is superior to secretin-enhanced cholangio-MRI to establish the etiology of idiopathic acute pancreatitis"],"prefix":"10.1055","volume":"08","author":[{"given":"Juan J.","family":"Vila","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Javier Jim\u00e9nez","family":"Mendioroz","sequence":"additional","affiliation":[{"name":"Digestive Radiology Unit, Radiology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Yeaton","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Department, Carilion Clinic, Roanoke, Virginia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I\u00f1aki","family":"Fern\u00e1ndez-Uri\u00e9n","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis Garc\u00eda","family":"Sanchotena","sequence":"additional","affiliation":[{"name":"Digestive Radiology Unit, Radiology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Go\u00f1i","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta G\u00f3mez","family":"Alonso","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Carrascosa","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Borda","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Prieto","sequence":"additional","affiliation":[{"name":"Biliary and Pancreatic Diseases Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Urman","sequence":"additional","affiliation":[{"name":"Biliary and Pancreatic Diseases Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 M","family":"Zozaya","sequence":"additional","affiliation":[{"name":"Endoscopy Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"},{"name":"Biliary and Pancreatic Diseases Unit, Gastroenterology Dpt, Complejo Hospitalario de Navarra, Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,10,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1056\/NEJM199404283301706","article-title":"Acute pancreatitis","volume":"330","author":"W Steinberg","year":"1994","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1056\/NEJM199202273260902","article-title":"Biliary sludge as a cause of acute pancreatitis","volume":"326","author":"S P Lee","year":"1992","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4253\/wjge.v2.i4.107","article-title":"Endoscopic ultrasonography and idiopathic acute pancreatitis","volume":"2","author":"J J Vila","year":"2010","journal-title":"World J Gastrointest Endosc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0889-8553(05)70074-1","article-title":"Causes of acute and recurrent pancreatitis. 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