{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T13:04:29Z","timestamp":1773839069021,"version":"3.50.1"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2002Large prolapse-related lesions (LPRL) of the sigmoid colon have been documented histologically but may not be readily recognized endoscopically.<\/jats:p><jats:p>\n          Methods\u2002Colonic lesions referred for endoscopic mucosal resection (EMR) were enrolled prospectively. Endoscopic features were carefully documented prior to resection. Final diagnosis was made based on established histologic criteria, including vascular congestion, hemosiderin deposition, fibromuscular hyperplasia, and crypt distortion.<\/jats:p><jats:p>\n          Results\u2002Of 134 large (\u200a\u2265\u200a20\u200amm) sigmoid lesions, 12 (9.0\u200a%) had histologic features consistent with mucosal prolapse. Distinct endoscopic features were: broad-based morphology; vascular pattern obscured by dusky hyperemia; blurred crypts of varying size and shape; and irregular spacing of sparse crypts. Focal histologic dysplasia was identified in 6 of 12 lesions (50.0\u200a%).<\/jats:p><jats:p>\n          Conclusions\u2002LPRL of the sigmoid colon exhibit a distinct endoscopic profile. Although generally non-neoplastic, dysplasia may be present, warranting consideration of EMR.<\/jats:p>","DOI":"10.1055\/a-1248-2175","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T23:05:52Z","timestamp":1600815952000},"page":"652-657","source":"Crossref","is-referenced-by-count":1,"title":["Large prolapse-related lesions of the sigmoid colon"],"prefix":"10.1055","volume":"53","author":[{"given":"W. Arnout","family":"van Hattem","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal","family":"Shahidi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"},{"name":"Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia"},{"name":"Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergei","family":"Vosko","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iddo","family":"Bar-Yishay","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Schoeman","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayenaaz","family":"Sidhu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"},{"name":"Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan","family":"McLeod","sequence":"additional","affiliation":[{"name":"Department of Pathology, Westmead Hospital, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Bourke","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia"},{"name":"Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,9,22]]},"reference":[{"key":"ref1","first-page":"370","article-title":"Prolapsing mucosal polyps: an underrecognized form of colonic polyp-a clinicopathological study of 15 cases","volume":"97","author":"D A Tendler","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0016-5107(85)72043-3","article-title":"Polypoid lesions associated with diverticular disease of the sigmoid colon","volume":"31","author":"G 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resection: a new classification and analysis of risk factors","volume":"66","author":"N G Burgess","year":"2017","journal-title":"Gut"}],"container-title":["Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1248-2175.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T22:38:41Z","timestamp":1622068721000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1248-2175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,22]]},"references-count":13,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2021,5,26]]},"published-print":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1248-2175","relation":{},"ISSN":["0013-726X","1438-8812"],"issn-type":[{"value":"0013-726X","type":"print"},{"value":"1438-8812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,22]]}}}