{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T04:49:06Z","timestamp":1766292546063},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rofo"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>\n            Background\u2002Despite tremendous improvement in molecular properties over the last century, intravascular injection of iodinated contrast material may still have systemic and hemodynamic consequences. Patients with pre-existing renal insufficiency may be at risk for acute kidney injury, which may be associated with an increased risk of the need for dialysis and mortality in the long term. Many questions as to the physiological pathways, optimal definition, and incidence of contrast-induced acute kidney injury remain open. These uncertainties are reflected in the changing landscape of this field in terms of nomenclature, research, and clinical practice.<\/jats:p><jats:p>\n            Methods\u2002Clinical practice guidelines for the prevention of post-contrast acute kidney injury all recommend giving prophylaxis in the form of intravenous hydration to high-risk patients. Solid evidence for this strategy is lacking. This article gives an overview of the changing landscape of post-contrast acute kidney injury and prophylactic intravenous hydration, with the aim of supporting informed decision-making in clinical practice.<\/jats:p><jats:p>\n            Results\u2002Recent data have caused a shift in guideline recommendations: 90\u200a% of patients formerly considered high-risk for contrast-induced acute kidney injury no longer qualify for prophylaxis. The remaining high-risk patients, with severe chronic kidney disease, represent a vulnerable population for whom intravenous hydration may provide some benefits but also carries risk.<\/jats:p><jats:p>\n            Conclusion\u2002Intravenous hydration may benefit \u2018new\u2019 high-risk patients. However, it also confers risk. A dual approach to screening patients will help avoid this risk in clinical practice.<\/jats:p><jats:p>\n            Key Points:\u2002<\/jats:p><jats:p>\n            Citation Format\n          <\/jats:p>","DOI":"10.1055\/a-1248-9178","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T00:22:23Z","timestamp":1608164543000},"page":"151-159","source":"Crossref","is-referenced-by-count":12,"title":["Post-Contrast Acute Kidney Injury and Intravenous Prophylactic Hydration: An Update"],"prefix":"10.1055","volume":"193","author":[{"given":"Estelle Claire","family":"Nijssen","sequence":"additional","affiliation":[{"name":"Radiology & Nuclear Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Rennenberg","sequence":"additional","affiliation":[{"name":"Internal Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patty","family":"Nelemans","sequence":"additional","affiliation":[{"name":"Epidemiology, Maastricht University, Maastricht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"van Ommen","sequence":"additional","affiliation":[{"name":"Cardiology, Maastricht University Medical Centre+, Maastricht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim E.","family":"Wildberger","sequence":"additional","affiliation":[{"name":"Radiology & Nuclear Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,12,16]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1001\/jama.1923.02640330004002","article-title":"Roentgenography of urinary tract during excretion of sodium 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Fortschritte auf dem Gebiet der R\u00f6ntgenstrahlen und der bildgebenden Verfahren"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1248-9178.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T06:01:54Z","timestamp":1611900114000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1248-9178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,16]]},"references-count":45,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2021,1,28]]},"published-print":{"date-parts":[[2021,2]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1248-9178","relation":{},"ISSN":["1438-9029","1438-9010"],"issn-type":[{"value":"1438-9029","type":"print"},{"value":"1438-9010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,16]]}}}