{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:32:47Z","timestamp":1740126767869,"version":"3.37.3"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Hintergrund\u2002Die Kupplungsvorrichtung f\u00fcr mikrovaskul\u00e4re Anastomosen hat in der freien Gewebetransplantation weite Verbreitung gefunden. Ziel der Arbeit ist der Vergleich der Thromboserate und des Transplantatversagens in Abh\u00e4ngigkeit von der Anastomosentechnik an einem gro\u00dfen Kopf-Hals-Tumorzentrum.<\/jats:p><jats:p>\n          Material und Methoden\u2002Retrospektive Auswertung von allen Patienten, die im Zeitraum von 2001\u20132019 eine freie Lappenrekonstruktion erhalten haben. Rekonstruktionstyp, Empf\u00e4ngergef\u00e4\u00dfe, Anzahl an Venenanastomosen, Coupler-Gr\u00f6\u00dfe und Operationszeit wurden untersucht. Wir verglichen die Raten an Venenthrombosen zwischen handgen\u00e4hten und gekoppelten Anastomosen sowie die Rate des Transplantatversagens.<\/jats:p><jats:p>\n          Ergebnisse\u2002Insgesamt wurden 403 freie Lappenrekonstruktionen \u00fcber einen Zeitraum von 17 Jahren durchgef\u00fchrt. Die ven\u00f6se Anastomose wurde bei 113 Lappen in Einzelknopftechnik gen\u00e4ht und in 290 F\u00e4llen mittels Coupler durchgef\u00fchrt. Die Rate der Venenthrombosen, die eine umgehende chirurgische Revision erforderten, betrug in der gen\u00e4hten Gruppe 6,2\u200a% (7\/113), verglichen mit 7,6\u200a% in der gekoppelten Gruppe (22\/290; p\u200a=\u200a0,627). Bei einer allgemeinen Erfolgsrate von 95,0\u200a% (383\/403) lag die Rate des Transplantatversagens jeweils bei 3,6\u200a% (4\/113) und 5,5\u200a% (16\/290; p\u200a=\u200a0,421). Die Operationszeit war mit 680\u200a\u00b1\u200a144 Minuten in der handgen\u00e4hten Gruppe und 688\u200a\u00b1\u200a167 Minuten in der Coupler-Gruppe vergleichbar (p\u200a=\u200a0,678).<\/jats:p><jats:p>\n          Schlussfolgerungen\u2002Bei \u00e4hnlichen Erfolgsraten ist der Coupler als wirksame Alternative zur ven\u00f6sen Anastomose in Einzelnahttechnik zu sehen. Aufgrund der allgemein niedrigen Rate an Stielthrombosen in beiden Gruppen k\u00f6nnen wir den Einfluss der Anastomosentechnik nicht von m\u00f6glichen St\u00f6rvariablen trennen.<\/jats:p>","DOI":"10.1055\/a-1253-8392","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T22:37:32Z","timestamp":1600123052000},"page":"453-459","source":"Crossref","is-referenced-by-count":0,"title":["Thrombose gen\u00e4hter vs. gekoppelter Anastomosen bei\u00a0mikrovaskul\u00e4ren Kopf- und Halsrekonstruktionen"],"prefix":"10.1055","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0741-4049","authenticated-orcid":false,"given":"Matti","family":"Sievert","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Koch","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Goncalves","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Richter","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalie","family":"Tamse","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarina K.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoniu-Oreste","family":"Gostian","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Traxdorf","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uli","family":"Harr\u00e9us","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenheilkunde, Kopf-Hals-Gesichtschirurgie, Asklepios-Stadtklinik Bad T\u00f6lz, Deutschland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinrich","family":"Iro","sequence":"additional","affiliation":[{"name":"Hals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universit\u00e4tskliniken Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, 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