{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T15:55:24Z","timestamp":1648914924027},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Geburtshilfe Neonatol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ziel dieser Studie ist es, ein kritisches postnatales Outcome als\n                        Pr\u00e4diktor f\u00fcr die Entwicklung einer hypoxisch\n                        isch\u00e4mischen Enzephalopathie (HIE) zu evaluieren.<\/jats:p><jats:p>\n          Methodik Auf Basis der Daten der hessischen Perinatalerhebung aus dem\n                        Jahr 2016 mit 52\u2009122 Geburten (Lebendgeborene Einlinge,\n                        \u2265\u200937+0 Schwangerschaftswochen) wurden die\n                        F\u00e4lle mit kritischem Outcome identifiziert. Kriterien waren ein\n                        APGAR-Score &lt;5 nach 5\u2009Minuten in Kombination mit einem pH\n                        &lt;7,00 bzw. Basendefizit &gt;16,0\u2009mmol\/L. Diese\n                        F\u00e4lle wurden mit den HIE-F\u00e4llen aus der Neonatalerhebung\n                        zusammengef\u00fchrt. Es wurden die Odds Ratio sowie\n                        Sensitivit\u00e4t\/Spezifit\u00e4t und positiver\n                        (ppW)\/negativer(npW) Vorhersagewert berechnet. Durch Evaluation des\n                        Geburtsverlaufes und des subpartalen CTG wurde die potentielle\n                        Vermeidbarkeit des Kritischen Outcomes\/hypoxisch\n                        isch\u00e4mischen Enzephalopathie \u00fcberpr\u00fcft.<\/jats:p><jats:p>\n          Ergebnisse Die Inzidenz der F\u00e4lle mit kritischem Outcome\n                        (n=11) und derer mit hypoxisch isch\u00e4mischen Enzephalopathie\n                        (n=29) ist gering. Nach Zusammenf\u00fchrung der Daten aus der\n                        Perinatal- respektive Neonatalerhebung ergaben sich eine\n                        Sensitivit\u00e4t von 10,34%, eine Spezifit\u00e4t von\n                        99,98%, ein positiver bzw. negativer pr\u00e4diktiver Wert von\n                        27,35, bzw. 99,95%. In nahezu einem Drittel der F\u00e4lle mit\n                        kritischem Outcome (4\/11) oder hypoxisch isch\u00e4mischen\n                        Enzephalopathie (9\/29) fanden sich Hinweise auf eine potentielle\n                        Vermeidbarkeit.<\/jats:p><jats:p>\n          Schlussfolgerungen Ein postnataler Depressionszustand f\u00fchrt\n                        h\u00e4ufiger zur Diagnose einer HIE als eine schwere Azidose im\n                        Nabelschnurblut. Da ein Drittel der F\u00e4lle vermeidbar erscheinen,\n                        kann die fach\u00fcbergreifende Einzelfallanalyse bei kritischem\n                        Neugeborenenstatus zur Optimierung der Geburtshilfe auch im Rahmen der\n                        externen Qualit\u00e4tssicherung (QS) zielf\u00fchrend sein.<\/jats:p>","DOI":"10.1055\/a-1258-4639","type":"journal-article","created":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T23:04:29Z","timestamp":1602111869000},"page":"360-366","source":"Crossref","is-referenced-by-count":0,"title":["Kritisches Outcome und Hypoxisch-Isch\u00e4mische Enzephalopathie\n                    (HIE) \u2013 Ein Thema der Qualit\u00e4tssicherung"],"prefix":"10.1055","volume":"224","author":[{"given":"Stephan","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Perinatale Medizin, Neuk\u00f6lln,\n                    Berlin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Misselwitz","sequence":"additional","affiliation":[{"name":"Gesch\u00e4ftsstelle Qualit\u00e4tssicherung Hessen (GQH),\n                    Eschborn"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxanne","family":"Schuster","sequence":"additional","affiliation":[{"name":"Gesch\u00e4ftsstelle Qualit\u00e4tssicherung Hessen (GQH),\n                    Eschborn"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lothar","family":"Schrod","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Kinder- und Jugendmedizin, Klinikum Frankfurt\n                    H\u00f6chst GmbH, Frankfurt am Main"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,10,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0028-2243(94)90075-2","article-title":"The birth survey in Germany \u2014 education and quality control in\n                    perinatology","volume":"54","author":"W K\u00fcnzel","year":"1994","journal-title":"European Journal of Obstetrics & Gynecology and Reproductive\n                    Biology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1055\/s-2005-837594","article-title":"Optimiert die Fetalblutanalyse die Qualit\u00e4t der geburtshilflichen\n                    Versorgung?","volume":"65","author":"S Schmidt","year":"2005","journal-title":"Geburtsh Frauenheilk"},{"key":"ref3","first-page":"899","article-title":"A randomized trial of intrapartum electronic fetal heart rate monitoring versus\n                    intermittent auscultation","volume":"81","author":"A M Vintzileos","year":"1993","journal-title":"Obstet Gynecol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0002-9378(97)70385-5","article-title":"Intrapartum fetal asphyxia. 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