{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T10:39:32Z","timestamp":1707820772035},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pneumologie"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>\n          Einleitung\u2002Bei Patient*innen mit fibrosierenden Lungenerkrankungen ist neben der Dyspnoe eines der Hauptsymptome dieses Patient*innenkollektives ein trockener Husten. Unklar ist allerdings, wie die 24-Stunden-Variablit\u00e4t dieser Symptomatik ist und ob andere Auskultationsph\u00e4nomene \u00fcber den Tagesverlauf zu eruieren sind.<\/jats:p><jats:p>\n          Methodik\u2002Bei Patient*innen mit fibrosierenden Lungenerkrankungen wurde eine Langzeitauskultation (LEOSound, L\u00f6wenstein Medical GmbH &amp; Co. KG, Medizin-Elektronik, Bad Ems, Deutschland) \u00fcber 24 Stunden durchgef\u00fchrt. Dabei wurden sowohl Husten als auch Giemen erfasst. Wesentlich war die Betrachtung in 12-Stunden-Phasen (Tag und Nacht). Die Erfassung erfolgte in Epochen (mindestens ein Ereignis in 30 Sekunden). <\/jats:p><jats:p>\n          Ergebnisse\u2002Insgesamt wurden 20 Patient*innen eingeschlossen (6 mit nichtspezifischer interstitieller Pneumonie und 14 mit idiopathischer pulmonaler Fibrose). Es wurden pro 24 Stunden im Mittel 166 Hustenepochen erfasst (Tag\/Nacht 116\/50; P\u200a&lt;\u200a0,001). Zudem wurden 203 Epochen von Giemen erfasst (Tag\/Nacht 84\/119; P\u200a=\u200a0,273). Die Auskultationsph\u00e4nomene waren weder mit den Werten der Spirometrie, der Ganzk\u00f6rperplethysmografie noch der Diffusionskapazit\u00e4t korreliert.<\/jats:p><jats:p>\n          Diskussion\u2002Die Studie zeigt das klinische Potenzial der Langzeitauskultation bei fibrosierenden Lungenerkrankungen. Insbesondere zeigt die Studie die Bedeutsamkeit des Symptoms Husten. Dabei zeigt sich eine Abnahme des Hustens in der Nacht im Vergleich zum Tag. Im Gegensatz dazu dokumentiert sich allerdings ein n\u00e4chtlich verst\u00e4rktes Giemen, dessen Bedeutung f\u00fcr die klinische Praxis noch unklar bleiben muss. Schlie\u00dflich ergab sich kein Zusammenhang zwischen der Krankheitsschwere, gemessen an der Funktionsdiagnostik, und der Hustensymptomatik.<\/jats:p>","DOI":"10.1055\/a-1266-6408","type":"journal-article","created":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T23:35:41Z","timestamp":1604532941000},"page":"337-343","source":"Crossref","is-referenced-by-count":1,"title":["Tag-\/Nachtvariabilit\u00e4t von Hustenereignissen bei interstitiellen Lungenerkrankungen"],"prefix":"10.1055","volume":"75","author":[{"given":"M.","family":"Berger","sequence":"additional","affiliation":[{"name":"Kliniken der Stadt K\u00f6ln gGmbH, Abteilung f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke, Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Wollsching-Strobel","sequence":"additional","affiliation":[{"name":"Kliniken der Stadt K\u00f6ln gGmbH, Abteilung f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke, Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Majorski","sequence":"additional","affiliation":[{"name":"Kliniken der Stadt K\u00f6ln gGmbH, Abteilung f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke, Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. 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B.","family":"Schwarz","sequence":"additional","affiliation":[{"name":"Kliniken der Stadt K\u00f6ln gGmbH, Abteilung f\u00fcr Pneumologie, Universit\u00e4t Witten\/Herdecke, Fakult\u00e4t f\u00fcr Gesundheit, K\u00f6ln"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,11,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1164\/rccm.201308-1483ST","article-title":"An official American Thoracic Society\/European Respiratory Society statement: Update of the international multidisciplinary classification of the idiopathic interstitial pneumonias","volume":"188","author":"W D Travis","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1164\/ajrccm.165.2.ats019","article-title":"American Thoracic Society\/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic 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