{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,18]],"date-time":"2024-08-18T16:10:05Z","timestamp":1723997405959},"reference-count":54,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tierarztl Prax Ausg K Kleintiere Heimtiere"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Ein 6-j\u00e4hriger Galgo-Espa\u00f1ol-R\u00fcde wurde aufgrund hochgradiger Dyspnoe vorgestellt. Nach r\u00f6ntgenologischer und sonografischer Diagnose eines Thoraxergusses erfolgte eine Thorakozentese, bei der 4\u2005l milchig-r\u00f6tliche Fl\u00fcssigkeit abgesogen wurden. Die klinisch-chemische Analyse ergab ein modifiziertes Transsudat mit erh\u00f6htem Triglyzeridgehalt, bei der zytologischen Untersuchung zeigten sich degenerierte neutrophile Granulozyten, einige Lymphozyten und Makrophagen sowie Chylomikronen. Es wurde eine Thoraxdrainage gelegt. Aufgrund des computertomografischen Befunds vergr\u00f6\u00dferter Sternallymphknoten und verdickter parietaler und viszeraler Pleuralbl\u00e4tter bei unauff\u00e4lligem Lungengewebe fiel die Entscheidung zur Thorakoskopie, bei der disseminierte herdf\u00f6rmige Proliferationen an der Pleura auffielen. Die histopathologische Untersuchung von Bioptaten ergab eine granulomat\u00f6se Pleuritis mit Hinweis auf intral\u00e4sionales, polarisationsoptisch anisotropes Fremdmaterial. Durch die energiedispersive R\u00f6ntgenmikroanalyse wurden rasterelektronenmikroskopisch stark kalziumhaltige Fremdmaterialien in den granulomat\u00f6sen Herden nachgewiesen. Die erweiterte Anamnese ergab, dass der Hund 15\u2005Monate zuvor einige Zeit in unmittelbarer N\u00e4he einer Baustelle gelebt hatte und kalkzementhaltige St\u00e4ube eingeatmet haben k\u00f6nnte. Eine Behandlung mit Prednisolon wurde nach 10\u2005Wochen wegen gastrointestinaler Nebenwirkungen abgesetzt. Nach weiteren 4\u2005Monaten kam es zu einem Rezidiv des Chylothorax. Der erneute Versuch einer immunsuppressiven Therapie mit Prednisolon und Ciclosporin musste wieder wegen Nebenwirkungen abgesetzt werden. Im weiteren Verlauf entwickelte der Hund eine Pneumonie und wurde auf Wunsch der Besitzerin euthanasiert.<\/jats:p>","DOI":"10.1055\/a-1274-9232","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T00:41:44Z","timestamp":1607128904000},"page":"454-461","source":"Crossref","is-referenced-by-count":0,"title":["Granulomat\u00f6se Pleuritis und Chylothorax durch Kalzitinhalation bei einem Galgo Espa\u00f1ol"],"prefix":"10.1055","volume":"48","author":[{"given":"Sonja","family":"Kramer","sequence":"additional","affiliation":[{"name":"Evidensia Tier\u00e4rztliche Klinik f\u00fcr Kleintiere, Norderstedt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Wohlsein","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie, Tier\u00e4rztliche Hochschule Hannover"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inge","family":"Schmitz","sequence":"additional","affiliation":[{"name":"Georgius Agricola Stiftung Ruhr, Institut f\u00fcr Pathologie, Ruhr-Universit\u00e4t Bochum, Bochum"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilva","family":"Drumm","sequence":"additional","affiliation":[{"name":"VetRad Partnerschaftsgesellschaft, Gie\u00dfen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadja","family":"Spies","sequence":"additional","affiliation":[{"name":"Evidensia Tier\u00e4rztliche Klinik f\u00fcr Kleintiere, Norderstedt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Lockemann","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Rechtsmedizin, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Nickel","sequence":"additional","affiliation":[{"name":"Evidensia Tier\u00e4rztliche Klinik f\u00fcr Kleintiere, 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Heimtiere"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1274-9232.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,18]],"date-time":"2024-08-18T15:42:23Z","timestamp":1723995743000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1274-9232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":54,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2020,12,4]]},"published-print":{"date-parts":[[2020,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1274-9232","relation":{},"ISSN":["1434-1239","2567-5842"],"issn-type":[{"type":"print","value":"1434-1239"},{"type":"electronic","value":"2567-5842"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}